US5133703A
Expired / Lapsed
US
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Process and apparatus for collecting blood of a patient for autotransfusion
Assignee: BOEHRINGER LABORATORIES A Corp OF COMMONWEALTH OF PENNSYLVANIA
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Filing: 1990-12-13
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Granted: 1992-07-28
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Expires: 2010-12-13
Abstract
Abstract A process and apparatus is provided for collecting a patient's blood for re-use of autotransfusion, in which blood is collected from a patient and delivered for treatment in a container, outside the patient, for later re-use or retransfusion to the patient. The treatment given to the blood before autotransfusion may reside in treating the blood to resist coagulation, treating the blood for removal of fats from the blood, or in removing other substances from the blood. The treatment, insofar as it is used to cause the blood to resist coagulation, includes withdrawing calcium ions from the blood and replacing them with other ions in sufficiently small quantities that the amount of other substance that is added to the blood is not harmful, preferably by passing the blood through a bed of ion exchange polymeric resin material. Insofar as fats are moved from the blood, the treatment includes collecting blood from the patient and wicking fats from the blood by means of a hydrophobic lipophilic wick. Other treatments to the blood, which accomplish the removal of other substances from the blood will also be apparent.
Inventors
- 👤 John R. Boehringer
- 👤 John Karpowicz
- 👤 Jeffrey Bence
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 20:39
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3621; A61M1/3627; A61M1/3633; A61M1/60; A61M1/61; A61M2202/00; A61M2202/08; Y; Y10; Y10S; Y10S210/00; Y10S210/902
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
159 words
Apparatus for collecting blood of a patient for re-use, comprising: (a) a container for receiving blood from a body of a patient; (b) a delivery line for delivery patient blood to the container; and (c) means disposed in fluid communication with the container for causing the blood to resist coagulation, said means including a quantity of cation ion exchange polymeric resin material in sufficient amounts to replace calcium ions in the blood with monovalent or another divalent cation, with said quantity of ion exchange resin material being arranged in said container as a conduit for passage of blood therethrough, wherein said conduit includes a sleeve-like member having an inlet and an outlet, wherein said sleeve-like member has an elongate body and surrounds said quantity of ion exchange resin material, generally imperforate to blood passing therethrough, with perforate inlet and exit ends, wherein said inlet to said sleeve-like member has a portion of greater cross-sectional dimension than said elongate body.
Claim 2
Dependent Claim
159 words
Apparatus for collecting blood of a patient for re-use, comprising: (a) a container for receiving blood from a body of a patient; (b) a delivery line for delivery patient blood to the container; and (c) means disposed in fluid communication with the container for causing the blood to resist coagulation, said means including a quantity of cation ion exchange polymeric resin material in sufficient amounts to replace calcium ions in the blood with monovalent or another divalent cation, with said quantity of ion exchange resin material being arranged in said container as a conduit for passage of blood therethrough, wherein said conduit includes a sleeve-like member having an inlet and an outlet, wherein said sleeve-like member has an elongate body and surrounds said quantity of ion exchange resin material, generally imperforate to blood passing therethrough, with perforate inlet and exit ends, wherein said inlet to said sleeve-like member has a portion of greater cross-sectional dimension than said elongate body.
Claim 3
Dependent Claim
49 words
The apparatus of claim 1, wherein said ion exchange polymeric resin material comprises a cation exchange resin substantially completely of the sodium salt form thereof, whereby the calcium ion of the blood is substantially substituted in the cation exchange resin in exchange for an equivalent amount of sodium ions.
Claim 4
Dependent Claim
26 words
The apparatus of claim 1, including suction means for drawing a negative pressure on said container for having patient blood drawn thereinto through said delivery line.
Claim 5
Dependent Claim
37 words
The apparatus of claim 1, including fat removal means disposed in the container, for removing fatty substances from the blood; said fat removal means including a hydrophobic lipophilic absorbing means for absorbing liquid fats from the blood.
Claim 6
Dependent Claim
23 words
The apparatus of claim 3, wherein said container comprises a generally flexible bag-like member, said flexible bag-like member having an interior and exterior.
Claim 7
Dependent Claim
44 words
The apparatus of claim 3, wherein said container comprises a first vessel disposed within a second vessel, to define a reduced pressure zone between the outside of the first vessel and the inside of the second vessel, with means hermetically sealing closed said zone.
Claim 8
Dependent Claim
28 words
The apparatus of claim 4, wherein said absorbing means is comprised of a polymeric material selected from the group consisting of polyethylene, polypropylene, polystyrene, polyvinylchloride, tetrafluoroethylene and silicone.
Claim 9
Dependent Claim
15 words
The apparatus of claim 4, wherein said absorbing means is comprised of a polymeric material.
Claim 10
Dependent Claim
15 words
The apparatus of claim 4, wherein said absorbing means is comprised of the polymer polyethylene.
Claim 11
Dependent Claim
42 words
The apparatus of claim 4, wherein said absorbing means comprises a material having a surface energy sufficient to allow a fatty substance to be absorbed and spread therein, but will resist more hydrophilic components of blood to be absorbed and spread therein.
Claim 12
Dependent Claim
29 words
The apparatus of claim 4, wherein said fat removal means is of generally sleeve-like construction, disposed about the elongate body which surrounds the quantity of ion exchange resin material.
Claim 13
Dependent Claim
49 words
The apparatus of claim 4, wherein said ion exchange polymeric resin material comprises a cation exchange resin substantially completely of the sodium salt form thereof, whereby the calcium ion of the blood is substantially absorbed on the cation exchange resin in exchange for an equivalent amount of sodium ions.
Claim 14
Dependent Claim
26 words
The apparatus of claim 4, including suction means for drawing a negative pressure on said container for having patient blood drawn thereinto through said delivery line.
Claim 15
Dependent Claim
23 words
The apparatus of claim 4, wherein said container comprises a generally flexible bag-like member, said flexible bag-like member having an interior and exterior.
Claim 16
Dependent Claim
26 words
The apparatus of claim 4, wherein an identification zone is provided on the exterior of said flexible bag-like member, including means for facilitating patient identification thereon.
Claim 17
Dependent Claim
44 words
The apparatus of claim 4, wherein said container comprises a first vessel disposed within a second vessel, to define a reduced pressure zone between the outside of the first vessel and the inside of the second vessel, with means hermetically sealing closed said zone.
Claim 18
Dependent Claim
26 words
The apparatus of claim 5, wherein an identification zone is provided on the exterior of said flexible bag-like member, including means for facilitating patient identification thereon.
Claim 19
Dependent Claim
21 words
The apparatus of claim 4, wherein said fat removal means comprises the conduit directly supporting said quantity of ion exchange material.
Claim 20
Dependent Claim
93 words
Apparatus for collecting blood of a patient for re-use, comprising: (a) a container for receiving blood from a body of a patient; (b) a delivery line for delivering patient blood to the container; (c) including fat removal means disposed in fluid communication with the container, for removing fatty substances from the blood; said fat removal means including a hydrophobic lipophilic absorbing means for absorbing liquid fats from the blood and (d) said fat removal means comprising an elongate wick member for contacting fatty substances in the blood and spreading the fatty substances therein.
Claim 21
Dependent Claim
93 words
Apparatus for collecting blood of a patient for re-use, comprising: (a) a container for receiving blood from a body of a patient; (b) a delivery line for delivering patient blood to the container; (c) including fat removal means disposed in fluid communication with the container, for removing fatty substances from the blood; said fat removal means including a hydrophobic lipophilic absorbing means for absorbing liquid fats from the blood and (d) said fat removal means comprising an elongate wick member for contacting fatty substances in the blood and spreading the fatty substances therein.
Claim 22
Dependent Claim
28 words
The apparatus of claim 19, wherein said absorbing means is comprised of a polymeric material selected from the group consisting of polyethylene, polypropylene, polystyrene, polyvinylchloride, tetrafluoroethylene and silicone.
Claim 23
Dependent Claim
15 words
The apparatus of claim 19, wherein said absorbing means is comprised of the polymer polyethylene.
Claim 24
Dependent Claim
15 words
The apparatus of claim 19 wherein said absorbing means is comprised of a polymeric material.
Claim 25
Dependent Claim
39 words
The apparatus of claim 12, wherein said absorbing means comprises a material having a surface energy sufficient to allow a fatty substance to be absorbed and spread therein, but will not allow blood to be absorbed and spread therein.
Claim 26
Independent Claim
22 words
The apparatus of any one of claims 1 and 19-23, including releasable connector means for attachment of the apparatus to a support.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-07-28 | 1996-01-27 | 1996-07-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-07-28 | 2000-01-27 | 2000-07-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-07-28 | 2004-01-27 | 2004-07-28 | $7700.00 | Window Closed / Lapsed |