US5128137A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Therapeutic system for the transdermal or transmucous administration of active substances and the use thereof
Assignee: LTS Lohmann Therapie Systeme AG
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Filing: 1990-02-06
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Granted: 1992-07-07
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Expires: 2010-02-06
Abstract
Abstract The present invention relates to a therapeutic system for the transdermal or transmucous administration of active substances via an impermeable backing layer, a reservoir which at least partially comprises active substance, is double-layered and consists of separate parts, and a protective layer, whereby the two reservoir members (a) are positioned substantially parallely on top of each other, (b) are separated from each other by a removable intermediate layer being impermeable to the active substances of said reservoir members, (c) either comprise active substance or auxiliary agents or both at concentrations not corresponding to the distribution equilibrium.
Inventors
- 👤 Walter Muller
- 👤 Michael Roreger
- 👤 Heinrich Kindel
- 👤 Peter Bohnenkamper
- 👤 Heike Palm
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 06:42
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7084; A61K9/7092
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
148 words
In a therapeutic system for the transdermal or transmucous administration of an active substance comprising an impermeable backing layer, a reservoir which at least partially contains the active substance, which is double-layered and which comprises separate members, and a protective layer, wherein the two reservoir members (a) are positioned substantially parallel on top of one another, (b) are separated from each other by a removable intermediate layer which is impermeable to the active substance of said reservoir members, and (c) either contain active subtance or an auxiliary agent or both at concentrations not corresponding to the ultimate distribution equilibrium, the improvement which comprises bonding the two reservoir members to one another via a mask, and positioning the intermediate layer (b) between one reservoir member and said mask, said layer (b) being formed of folded foils which at least partially extend laterally beyond the surfaces of the reservoir members.
Claim 2
Dependent Claim
148 words
In a therapeutic system for the transdermal or transmucous administration of an active substance comprising an impermeable backing layer, a reservoir which at least partially contains the active substance, which is double-layered and which comprises separate members, and a protective layer, wherein the two reservoir members (a) are positioned substantially parallel on top of one another, (b) are separated from each other by a removable intermediate layer which is impermeable to the active substance of said reservoir members, and (c) either contain active subtance or an auxiliary agent or both at concentrations not corresponding to the ultimate distribution equilibrium, the improvement which comprises bonding the two reservoir members to one another via a mask, and positioning the intermediate layer (b) between one reservoir member and said mask, said layer (b) being formed of folded foils which at least partially extend laterally beyond the surfaces of the reservoir members.
Claim 3
Dependent Claim
118 words
In a therapeutic system for the transdermal or transmucous administration of an active substance comprising an impermeable backing layer, a reservoir which at least partially contains the active substance, which is double-layered and which comprises separate members, and a protective layer, wherein the two reservoir members (a) are positioned substantially parallel on top of one another, (b) are separated from each other by a removable intermediate layer which is impermeable to the active substance of said reservoir members, and (c) either contain active substance or an auxiliary agent or both at concentrations not corresponding to the ultimate distribution equilibrium, the improvement which comprises employing reservoir members which are self-adhesive, the intermediate layer of (b) being filled with gas.
Claim 4
Dependent Claim
118 words
In a therapeutic system for the transdermal or transmucous administration of an active substance comprising an impermeable backing layer, a reservoir which at least partially contains the active substance, which is double-layered and which comprises separate members, and a protective layer, wherein the two reservoir members (a) are positioned substantially parallel on top of one another, (b) are separated from each other by a removable intermediate layer which is impermeable to the active substance of said reservoir members, and (c) either contain active substance or an auxiliary agent or both at concentrations not corresponding to the ultimate distribution equilibrium, the improvement which comprises employing reservoir members which are self-adhesive, the intermediate layer of (b) being filled with gas.
Claim 5
Dependent Claim
17 words
A therapeutic system according to claim 1, wherein the intermediate layer (b) comprises a siliconized, flexible material.
Claim 6
Dependent Claim
16 words
A therapeutic system according to claim 1, wherein the intermediate layer (b) comprises a polymer-metal-composite foil.
Claim 7
Dependent Claim
24 words
A therapeutic system according to claim 1, wherein the mask is formed as a strip joining the longitudinal edges of the two reservoir members.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-07-07 | 1996-01-06 | 1996-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-07-07 | 2000-01-06 | 2000-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-07-07 | 2004-01-06 | 2004-07-07 | $7700.00 | Window Closed / Lapsed |