US5122670A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multilayer flow electrospray ion source using improved sheath liquid
Assignee: Thermo Finnigan LLC
•
Filing: 1991-05-17
•
Granted: 1992-06-16
•
Expires: 2011-05-17
Abstract
Abstract An electrospray ion source in which the liquid sample is sheathed with a sheath liquid which reduces the formation of water droplets and minimizes formation of high energy neutrals, resulting in improved signal-to-noise ratios.
Inventors
- 👤 Iain C. Mylchreest
- 👤 Mark E. Hail
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:18
CPC Classifications
H; H01; H01J; H01J49/00; H01J49/02; H01J49/10; H01J49/16; H01J49/165; G; G01; G01N; G01N30/00; G01N30/02; G01N30/62; G01N30/72; G01N30/7233; G01N30/724; G01N30/7266; G01N30/7293; G01N30/26; G01N30/38
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
85 words
An electrospray ion source of the type which includes an ionization chamber into which sheathed liquid sample is introduced and an adjacent low pressure region with means communicating between the ionization chamber and the lower pressure region whereby ions and gases in said ionization chamber flow into said region, the improvement comprising using a sheath liquid which has low surface tension, is compatible with liquid samples having high water percentage, is miscible with water, methanol and acetonitrile, and has a boiling point higher than water.
Claim 2
Dependent Claim
85 words
An electrospray ion source of the type which includes an ionization chamber into which sheathed liquid sample is introduced and an adjacent low pressure region with means communicating between the ionization chamber and the lower pressure region whereby ions and gases in said ionization chamber flow into said region, the improvement comprising using a sheath liquid which has low surface tension, is compatible with liquid samples having high water percentage, is miscible with water, methanol and acetonitrile, and has a boiling point higher than water.
Claim 3
Dependent Claim
15 words
An electrospray ion source as in claim 1 in which said sheath liquid is 2-methoxyethanol.
References Cited (Backward Citations)
US4885076A
Cited
US4861988A
Cited
US4935624A
Cited
US4977785A
Cited
US4994165A
Cited
US4982097A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-06-16 | 1995-12-16 | 1996-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-16 | 1999-12-16 | 2000-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-16 | 2003-12-16 | 2004-06-16 | $7700.00 | Window Closed / Lapsed |