US5120535A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oncostatin M and novel compositions having anti-neoplastic activity
Assignee: Oncogen LP
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Filing: 1987-05-04
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Granted: 1992-06-09
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Expires: 2007-05-04
Abstract
Abstract Novel compositions are provided for modulating growth, particularly of tumor cells, which compositions are combinations of Oncostatin M, and one or both of transforming growth factors or γ-interferons, or analogs thereof. In addition, a novel transforming growth factor is provided, designated TGF-β2, as well as methods for its preparation.
Inventors
- 👤 Hans Marquardt
- 👤 Joyce M. Zarling
- 👤 Mohammed Shoyab
- 👤 Marcia B. Hanson
- 👤 Mario N. Lioubin
- 👤 Thomas J. Brown
- 👤 Tatsuhiko Ikeda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:25
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/20; A61K38/204; A61K38/21; A61K38/217; C07K14/475; C07K14/495; C07K16/00; C07K16/18; C07K16/22; C07K16/24; C07K2319/00; C07K2319/70; C07K2319/74; C07K2319/75
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
36 words
A neoplastic cell proliferation inhibiting composition comprising a cell proliferation inhibiting amount of Oncostatin M in combination with an adjunctive agent consisting of at least one of interferon-γ, transforming growth factor in a physiologically acceptable carrier.
Claim 2
Dependent Claim
36 words
A neoplastic cell proliferation inhibiting composition comprising a cell proliferation inhibiting amount of Oncostatin M in combination with an adjunctive agent consisting of at least one of interferon-γ, transforming growth factor in a physiologically acceptable carrier.
Claim 3
Dependent Claim
20 words
A composition according to claim 1, wherein said Oncostatin M is at least 25 weight percent of the inhibiting combination.
References Cited (Backward Citations)
EP0169016A2
Cited
US4737580A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-06-09 | 1995-12-09 | 1996-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-09 | 1999-12-09 | 2000-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-09 | 2003-12-09 | 2004-06-09 | $7700.00 | Window Closed / Lapsed |