US5118602A
Expired / Lapsed
US
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Feline T-lymphotropic lentivirus assay
Assignee: University of California, San Diego
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Filing: 1990-11-16
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Granted: 1992-06-02
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Expires: 2010-11-16
Abstract
Abstract Compositions derived from a novel viral isolate designated feline T-lymphotropic lentivirus (FTLV) include the whole virus; proteins, polypeptides and, polynucleotide sequences derived from the virus; and antibodies to antigenic sites on the virus. These compositions are useful in a variety of techniques for the detection of and vaccination against FTLV. Detection methods disclosed include immunoassays for both the virus and antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses and subunit vaccines. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).
Inventors
- 👤 Niels C. Pedersen
- 👤 Janet K. Yamamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 10:05
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61K; A61K39/00; A61K39/12; A61K39/21; C12; C12N; C12N7/00; A61K2039/51; A61K2039/525; A61K2039/5252; A61K2039/555; A61K2039/55511; A61K2039/55516; A61K2039/5555; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/15011; C12N2740/15021; C12N2740/15022; C12N2740/15034; Y; Y10; Y10S; Y10S436/00; Y10S436/807
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
40 words
A method for diagnosing viral infection in a susceptible host, said method comprising: obtaining a physiological specimen from said host; and determining the presence of feline T-lymphotropic virus (FTLV) or antibodies to FTLV in a physiological specimen from said host.
Claim 2
Independent Claim
40 words
A method for diagnosing viral infection in a susceptible host, said method comprising: obtaining a physiological specimen from said host; and determining the presence of feline T-lymphotropic virus (FTLV) or antibodies to FTLV in a physiological specimen from said host.
Claim 3
Dependent Claim
18 words
A method as in claim 1, wherein FTLV is detected in the specimen by reaction with anti-FTLV antibody.
Claim 4
Independent Claim
74 words
A method for diagnosing viral infection in a susceptible host, said method comprising: obtaining a physiological specimen from the host; exposing the specimen to a solid phase having immobilized antigen characteristic of feline T-lymphotropic virus (FTLV), whereby anti-FTLV antibody in the specimen binds to said immobilized antigen; and exposing the solid phase to labeled anti- (anti-FTLV) antibody; and detecting binding of the label to the solid phase, said binding being diagnostic of viral infection.
Claim 5
Independent Claim
74 words
A method for diagnosing viral infection in a susceptible host, said method comprising: obtaining a physiological specimen from the host; exposing the specimen to a solid phase having immobilized antigen characteristic of feline T-lymphotropic virus (FTLV), whereby anti-FTLV antibody in the specimen binds to said immobilized antigen; and exposing the solid phase to labeled anti- (anti-FTLV) antibody; and detecting binding of the label to the solid phase, said binding being diagnostic of viral infection.
Claim 6
Dependent Claim
13 words
A method as in claim 3, wherein the label is a detectable enzyme.
Claim 7
Dependent Claim
12 words
A method as in claim 4, wherein the enzyme is a peroxidase.
Claim 8
Dependent Claim
11 words
A method as in claim 3, wherein the label is fluorescent.
References Cited (Backward Citations)
No citation records indexed.
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| 3.5 Years (Year 4) | 1995-06-02 | 1995-12-02 | 1996-06-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-02 | 1999-12-02 | 2000-06-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-02 | 2003-12-02 | 2004-06-02 | $7700.00 | Window Closed / Lapsed |