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US5116824A Expired / Lapsed US ⏱️ 0.0 years remaining

Biomaterial comprising a composite material of a chitosan derivative and collagen derivative

Assignee: Koken Co Ltd
•
Filing: 1990-10-29
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Granted: 1992-05-26
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Expires: 2010-10-29
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Abstract

Abstract A biomaterial excellent in biocompatibility comprising a composite material of an N-acylchitosan and collagen is described. This biomaterial is suitable for used as a wound dressing material, vascular prosthesis, artificial skin or hemostatic agent.

Inventors

  • 👤 Teruo Miyata
  • 👤 Kazuhiko Kodaira
  • 👤 Hitoshi Higashijima
  • 👤 Takashi Kimura
  • 👤 Yasuharu Noishiki

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 04:49
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/225; A61L15/42; A61L15/425; A61L27/00; A61L27/14; A61L27/26; A61L27/50; A61L27/507; A61L27/60; A61L2400/00; A61L2400/04

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 90 words
A wound dressing material comprising a composite material of an N-succinylchitosan and atelocollagen in a proportion of 50 to 90% by weight of the N-succinylchitosan to 10 to 50% by weight of the compound selected from the group consisting of atelocollagen, acetylated atelocollagen and methylated atelocollagen, the composite material being crosslinked and in the form of a sponge or film and the N-succinylchitosan being obtained by succinylation of chitosan prepared by deacetylation of chitin with a concentrated alkali to form a chitosan succinylated in a proportion of at least 55%.
Claim 2
Dependent Claim 90 words
A wound dressing material comprising a composite material of an N-succinylchitosan and atelocollagen in a proportion of 50 to 90% by weight of the N-succinylchitosan to 10 to 50% by weight of the compound selected from the group consisting of atelocollagen, acetylated atelocollagen and methylated atelocollagen, the composite material being crosslinked and in the form of a sponge or film and the N-succinylchitosan being obtained by succinylation of chitosan prepared by deacetylation of chitin with a concentrated alkali to form a chitosan succinylated in a proportion of at least 55%.
Claim 3
Dependent Claim 15 words
The wound dressing material according to claim 1 wherein the atelocollagen is acetylated or methylated.
Claim 4
Dependent Claim 35 words
The wound dressing material of claim 1, wherein the composite material further contains at least one member selected from the group consisting of chondroitin-4 sulfuric acid, dermatan sulfate, chondroitin-6 sulfuric acid, hyaluronic acid, and fibrin.

References Cited (Backward Citations)

US4415490A Cited
EP0038628A2 Cited
US4407787A Cited
US4350629A Cited
US4570629A Cited
US4559304A Cited
EP0138385A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-05-26 1995-11-25 1996-05-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-05-26 1999-11-25 2000-05-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-05-26 2003-11-25 2004-05-26 $7700.00 Window Closed / Lapsed

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