US5116495A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Capillary chromatography device
Assignee: OttoSensors Corp
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Filing: 1989-12-22
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Granted: 1992-05-26
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Expires: 2009-12-22
Abstract
Abstract The invention describes a new fabrication procedure of a capillary chromatography device with at least one sensor unit. The device contains at least one capillary column which is formed between a carrier and a cover layer, and which has at least one inlet and one outlet opening for a carrier phase and/or the sample. In addition, the invention describes a capillary chromatography device with at least one sensor, where the capillary columns with inlet and outlet openings and, if necessary, additional inlet, outlet and detector chambers, are formed between a carrier and a cover layer, which is deposited onto the carrier surface.
Inventors
- 👤 Otto J. Prohaska
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 10:14
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/60; G01N30/6095; G01N30/26; G01N30/38; G01N30/46; G01N30/461; G01N30/466; G01N30/6034
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
197 words
A capillary chromatography device for separating the components of a sample, said device comprising: means defining a capillary column for conducting the sample therethrough, the cross-section of said capillary column having a width less than or equal to 1 millimeter and a height less than or equal to 1 millimeter; at least one inlet and at least one outlet for conducting the sample into and out of said capillary column; at least one sensor located in said capillary column for measuring a characteristic of the sample; said means defining a capillary column including first and second walls, said first wall comprising a substrate and said second wall comprising a cover layer having opposite portions sealingly adhered to a surface of said substrate and partially upwardly bent portions therebetween, said cover layer having a thickness in the range of 0.50 micrometers to 3 micrometers and being formed of a material selected from the group of materials consisting of SiO x , SiO x N y , SiN y , TiO x , and TaO x , and TaO y , and where x can vary between 1 and 2 and where y can vary between 1 and 5.
Claim 2
Dependent Claim
197 words
A capillary chromatography device for separating the components of a sample, said device comprising: means defining a capillary column for conducting the sample therethrough, the cross-section of said capillary column having a width less than or equal to 1 millimeter and a height less than or equal to 1 millimeter; at least one inlet and at least one outlet for conducting the sample into and out of said capillary column; at least one sensor located in said capillary column for measuring a characteristic of the sample; said means defining a capillary column including first and second walls, said first wall comprising a substrate and said second wall comprising a cover layer having opposite portions sealingly adhered to a surface of said substrate and partially upwardly bent portions therebetween, said cover layer having a thickness in the range of 0.50 micrometers to 3 micrometers and being formed of a material selected from the group of materials consisting of SiO x , SiO x N y , SiN y , TiO x , and TaO x , and TaO y , and where x can vary between 1 and 2 and where y can vary between 1 and 5.
Claim 3
Dependent Claim
29 words
A capillary chromatography device as set forth in claim 1 wherein said substrate includes at least one groove etched therein for increasing the cross section of said capillary column.
Claim 4
Dependent Claim
27 words
A capillary device as set forth in claim 2 wherein the cross-sectional area of said groove is substantially less than the cross-sectional area of said capillary column.
Claim 5
Dependent Claim
23 words
A capillary chromatography device as set forth in claim 1 wherein said capillary column includes on its inner surface a separation enhancing layer.
Claim 6
Dependent Claim
20 words
A capillary device as set forth in claim 1 wherein said sensor is located between said inlet and said outlet.
Claim 7
Dependent Claim
59 words
A capillary device as set forth in claim 1 wherein said substrate and said cover layer together define a splitting system which includes an output opening whereby said sample may enter the capillary column through said inlet and a portion of said sample may travel through the capillary column and the remaining portion may travel through said output opening.
Claim 8
Dependent Claim
21 words
A capillary device as set forth in claim 1 wherein said cover layer determines the inner shape of said capillary column.
Claim 9
Dependent Claim
24 words
A capillary device as set forth in claim 1 wherein the height of said bent cover portions determines the height of said capillary channel.
Claim 10
Dependent Claim
22 words
A capillary device as set forth in claim 1 wherein said inlet and said outlet are formed by openings in the substrate.
Claim 11
Dependent Claim
20 words
A capillary chromatography device as set forth in claim 1 wherein said capillary column has the shape of a spiral.
Claim 12
Dependent Claim
21 words
A capillary chromatography device as set forth in claim 1 wherein said capillary column has the shape of a double helix.
Claim 13
Dependent Claim
18 words
A capillary chromatography device as set forth in claim 1 wherein said capillary column has a bifilar shape.
Claim 14
Dependent Claim
30 words
A capillary chromatography device as set forth in claim 1, 10, 11, or 12 wherein the cross-section of said capillary column changes continuously along the length of said capillary column.
Claim 15
Dependent Claim
30 words
A capillary chromatography device as set forth in claim 1, 10, 11, or 12 wherein the cross-section of said capillary column changes abruptly along the length of said capillary column.
Claim 16
Dependent Claim
28 words
A capillary chromatography device as set forth in claim 1 wherein said substrate and said cover layer define a plurality of capillary columns extending parallel to each other.
Claim 17
Dependent Claim
32 words
A capillary chromatography device as set forth in claim 1 wherein said substrate and said cover layer define a plurality of capillary columns extending in different directions and merging into each other.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-05-26 | 1995-11-25 | 1996-05-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-05-26 | 1999-11-25 | 2000-05-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-05-26 | 2003-11-25 | 2004-05-26 | $7700.00 | Window Closed / Lapsed |