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US5116361A Expired / Lapsed US ⏱️ 0.0 years remaining

Sulfonated polyethyleneoxide-substituted polymers with improved blood compatibility

Assignee: Korea Institute of Science and Technology
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Filing: 1990-06-07
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Granted: 1992-05-26
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Expires: 2010-06-07
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Abstract

Abstract Novel sulfonated polyethyleneoxide-substituted polymers having improved blood compatibility are provided. The polymers are produced by substituting a polymeric substrate having active sites of amide or acid amide group, such as polyurethane, polyamide and polyacrylamide, with sulfonated polyethyleneoxide PEO-SO 3 H. The polymers according to the present invention are valuable as construction materials of the artificial organs for the circulatory system in contact with blood, such as artificial hearts, artificial blood vessels, artificial kidneys, etc.

Inventors

  • 👤 Young-Ha Kim
  • 👤 Seo-Young Jeong
  • 👤 Kwang-Duk Ahn
  • 👤 Dong-Keun Han

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 16:23
CPC Classifications
G; G11; G11B; G11B5/00; G11B5/48; G11B5/49; A; A61; A61L; A61L33/00; A61L33/0076; A61L33/0082; A61L33/06; A61L33/068; B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0093; B01D67/00931; C; C08; C08G; C08G18/00; C08G18/06; C08G18/08; C08G18/0804; C08G18/0819; C08G18/0828; C08G18/10; C08G18/83; C08G65/00; C08G65/02; C08G65/04; C08G65/22; C08G65/32; C08G65/329; C08G65/334; C08G65/3344

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 27 words
A modified polymeric material having improved blood compatibility, comprising a polymeric substrate having sulfonated polyethylene oxide groups substituted for amide or acid amide groups of said substrate.
Claim 2
Dependent Claim 27 words
A modified polymeric material having improved blood compatibility, comprising a polymeric substrate having sulfonated polyethylene oxide groups substituted for amide or acid amide groups of said substrate.
Claim 3
Dependent Claim 24 words
The modified polymeric material of claim 1, wherein said polymeric substrate is selected from the group consisting of polyurethane, polyamide, polyacrylamide, and copolymers thereof.
Claim 4
Dependent Claim 34 words
The modified polymeric material of claim 1, wherein the substitution degree of the sulfonated polyethyleneoxide is 5-50% in the case of a bulk reaction and 50-95% in the case of a surface reaction, respectively.
Claim 5
Dependent Claim 26 words
A construction material of medical devices or instruments for use in contact with blood, comprising the modified polymeric material of any of claims 1 to 3.
Claim 6
Dependent Claim 15 words
An artificial heart comprising the modified polymeric material of any of claims 1 to 3.
Claim 7
Dependent Claim 16 words
An artificial blood vessel comprising the modified polymeric material of any of claims 1 to 3.
Claim 8
Dependent Claim 16 words
An artificial heart valve comprising the modified polymeric material of any of claims 1 to 3.
Claim 9
Dependent Claim 16 words
An artificial blood oxygenater comprising the modified polymeric material of any of claims 1 to 3.
Claim 10
Dependent Claim 15 words
An artificial kidney comprising the modified polymeric material of any of claims 1 to 3.
Claim 11
Dependent Claim 16 words
A blood vessel catheter comprising the modified polymeric material of any of claims 1 to 3.

References Cited (Backward Citations)

US3886947A Cited
US4743258A Cited
US4795475A Cited
US5017664A Cited
US4882148A Cited
US4965112A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-05-26 1995-11-25 1996-05-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-05-26 1999-11-25 2000-05-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-05-26 2003-11-25 2004-05-26 $7700.00 Window Closed / Lapsed

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