Laryngeal pacemaker

Claim 2

A laryngeal pacemaker comprising: a) a sensing electrode having adapted for electrical coupling to a first, normally functioning crico-arytenoid muscle and for providing electrical signals indicative of muscle activity thereof; b) a stimulating electrode having means for electrical coupling to a second, dysfunctional crico-arytenoid muscle; c) processing means coupled to receive the electrical signals provided by the sensing electrode for providing stimulating signals to the stimulating electrode in substantial synchronism with the electrical signals provided by the sensing electrode; the dysfunctional crico-arytenoid muscle, in pacemaker operation, being stimulated in substantial mirror image synchronism with the activity of the normally functioning crico-arytenoid muscle.

Claim 3

Pacemaker according to claim 1 wherein the processing means is implantable.

Claim 4

Pacemaker according to claim 1 wherein the electrodes are bipolar.

Claim 5

Pacemaker according to claim 1 wherein the processing means comprises: a) first means for providing an indication that the electrical signal provided on the sensing electrode has reached a predetermined level; and b) second means operatively coupled to and responsive to the first means for generating the stimulating signals.

Claim 6

Pacemaker according to claim 4 wherein the stimulating signals are biphase D.C. current pulses.

Claim 7

Pacemaker according to claim 5 wherein the current pulses have a duration of about 1 msec and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 8

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a first, normally functioning lateral crico-arytenoid muscle for providing electrical signals indicative of muscle activity thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a second, dysfunctional lateral crico-arytenoid muscle; c) implanatable circuit means for coupling to the electrodes for providing indications that electrical signals provided on the sensing electrode have reached a predetermined level and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the dysfunctional lateral crico-arytenoid muscle, in pacemaker operation, being stimulated in substantial mirror image synchronism with the activity of the normally functioning lateral crico-arytenoid muscle.

Claim 9

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a first, normally functioning lateral crico-arytenoid muscle for providing electrical signals indicative of muscle activity thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a second, dysfunctional lateral crico-arytenoid muscle; c) implanatable circuit means for coupling to the electrodes for providing indications that electrical signals provided on the sensing electrode have reached a predetermined level and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the dysfunctional lateral crico-arytenoid muscle, in pacemaker operation, being stimulated in substantial mirror image synchronism with the activity of the normally functioning lateral crico-arytenoid muscle.

Claim 10

Pacemaker according to claim 7 wherein the stimulating signals are biphase D.C. current pulses.

Claim 11

Pacemaker according to claim 8 wherein the current pulses have a duration of about 1 msec and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 12

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning one of a pair of crico-arytenoid muscles; b) artificially stimulating a dysfunctional one of the pair of crico-arytenoid muscles in substantial mirror image synchronism with the sensed electrical activity.

Claim 13

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning one of a pair of crico-arytenoid muscles; b) artificially stimulating a dysfunctional one of the pair of crico-arytenoid muscles in substantial mirror image synchronism with the sensed electrical activity.

Claim 14

A laryngeal pacemaker comprising: a) a sensing electrode having adapted for electrical coupling to a normally functioning muscle which contracts during inspiration and for providing electrical signals indicative of muscle activity thereof; b) a stimulating electrode having means for electrical coupling to a dysfunctional posterior crico-arytenoid muscle; c) processing means coupled to receive the electrical signals provided by the sensing electrode for providing stimulating signals to the stimulating electrode in substantial synchronism with the electrical signals provided by the sensing electrode; the dysfunctional posterior crico-arytenoid muscle, in pacemaker operation, being stimulated in substantial synchronism with the activity of the normally functioning muscle.

Claim 15

A laryngeal pacemaker comprising: a) a sensing electrode having adapted for electrical coupling to a normally functioning muscle which contracts during inspiration and for providing electrical signals indicative of muscle activity thereof; b) a stimulating electrode having means for electrical coupling to a dysfunctional posterior crico-arytenoid muscle; c) processing means coupled to receive the electrical signals provided by the sensing electrode for providing stimulating signals to the stimulating electrode in substantial synchronism with the electrical signals provided by the sensing electrode; the dysfunctional posterior crico-arytenoid muscle, in pacemaker operation, being stimulated in substantial synchronism with the activity of the normally functioning muscle.

Claim 16

Pacemaker according to claim 11 wherein the processing means is implantable.

Claim 17

Pacemaker according to claim 11 wherein the electrodes are bipolar.

Claim 18

Pacemaker according to claim 11 wherein the processing means comprises: a) first means for providing an indication that the electrical signal provided on the sensing electrode has reached a predetermined level; and b) second means operatively coupled to and responsive to the first means for generating the stimulating signals.

Claim 19

Pacemaker according to claim 14 wherein the stimulating signals are biphasic D.C. current pulses.

Claim 20

Pacemaker according to claim 15 wherein the current pulses have a duration of about 1 m-sec. and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 21

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a normally functioning muscle which contracts during inspiration and for providing electrical signals indicative of muscle activity thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a dysfunctional posterior crico-arytenoid muscle; c) implantable circuit means coupled to the electrodes for providing indications that electrical signals provided on the sensing electrode have reached a predetermined level and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the implantable circuit means causing the dysfunctional posterior crico-arytenoid muscle to be stimulated in substantial synchronism with the activity of the normally functioning muscle.

Claim 22

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a normally functioning muscle which contracts during inspiration and for providing electrical signals indicative of muscle activity thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a dysfunctional posterior crico-arytenoid muscle; c) implantable circuit means coupled to the electrodes for providing indications that electrical signals provided on the sensing electrode have reached a predetermined level and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the implantable circuit means causing the dysfunctional posterior crico-arytenoid muscle to be stimulated in substantial synchronism with the activity of the normally functioning muscle.

Claim 23

Pacemaker according to claim 17 wherein the stimulating signals are biphasic D.C. current pulses.

Claim 24

Pacemaker according to claim 18 wherein the current pulses have a duration of about 1 m-sec. and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 25

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning muscle which contracts during inspiration; b) artificially stimulating a dysfunctional posterior cricoarytenoid muscle in substantial synchronism with the sensed electrical activity.

Claim 26

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning muscle which contracts during inspiration; b) artificially stimulating a dysfunctional posterior cricoarytenoid muscle in substantial synchronism with the sensed electrical activity.

Claim 27

A laryngeal pacemaker comprising: a) a sensing electrode having adapted for electrical coupling to a first, normally functioning crico-arytenoid muscle and for providing electrical signals indicative of muscle activity thereof; b) a stimulating electrode having means for electrical coupling to a reconstructive muscle flap; c) processing means coupled to receive the electrical signals provided by the sensing electrode for providing stimulating signals to the stimulating electrode in substantial synchronism with the electrical signals provided by the sensing electrode; the reconstructive muscle flap, in pacemaker operation, being stimulated in substantial synchronism with the activity of the normally functioning crico-arytenoid muscle.

Claim 28

A laryngeal pacemaker comprising: a) a sensing electrode having adapted for electrical coupling to a first, normally functioning crico-arytenoid muscle and for providing electrical signals indicative of muscle activity thereof; b) a stimulating electrode having means for electrical coupling to a reconstructive muscle flap; c) processing means coupled to receive the electrical signals provided by the sensing electrode for providing stimulating signals to the stimulating electrode in substantial synchronism with the electrical signals provided by the sensing electrode; the reconstructive muscle flap, in pacemaker operation, being stimulated in substantial synchronism with the activity of the normally functioning crico-arytenoid muscle.

Claim 29

Laryngeal pacemaker according to claim 21 wherein the reconstructive muscle flap is a STRAP muscle.

Claim 30

Laryngeal pacemaker according to claim 22 wherein the STRAP muscle is one of a omohyoid, sternohyoid, thyrohyoid or sternothyroid muscle.

Claim 31

Laryngeal pacemaker according to claim 21 wherein the processing means is implantable.

Claim 32

Laryngeal pacemaker according to claim 21 wherein the electrodes are bipolar.

Claim 33

Laryngeal pacemaker according to claim 21 wherein the processing means comprises: a) first means for providing an indication that the electrical signal provided on the sensing electrode has reached a predetermined level; and b) second means operatively coupled to and responsive to the first means for generating the stimulating signals.

Claim 34

Laryngeal pacemaker according to claim 26 wherein the stimulating signals are biphasic D.C. current pulses.

Claim 35

Laryngeal pacemaker according to claim 27 wherein the current pulses have a duration of about 1 m-sec. and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 36

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning intrinsic laryngeal muscle; b) artificially stimulating a reconstructive muscle flap in substantial synchronism with the sensed electrical activity.

Claim 37

Laryngeal pacing method comprising the steps of: a) sensing electrical activity of a normally functioning intrinsic laryngeal muscle; b) artificially stimulating a reconstructive muscle flap in substantial synchronism with the sensed electrical activity.

Claim 38

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a normally functioning intrinsic muscle of the larynx and for providing electrical signals indicative of resting muscle tone thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a reconstructive muscle flap; c) implantable circuit means coupled to the electrodes having means for providing indications that electrical signals provided on the sensing electrode are within a range indicative of resting motor tone and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the implantable circuit means causing the reconstructive muscle flap to be stimulated to maintain the resting motor tone.

Claim 39

Laryngeal pacemaker comprising: a) an implantable bipolar sensing electrode having adapted for electrical coupling to a normally functioning intrinsic muscle of the larynx and for providing electrical signals indicative of resting muscle tone thereof; b) an implantable bipolar stimulating electrode having means for electrical coupling to a reconstructive muscle flap; c) implantable circuit means coupled to the electrodes having means for providing indications that electrical signals provided on the sensing electrode are within a range indicative of resting motor tone and for generating stimulating signals in response thereto, the implantable circuit means providing the stimulating signals in substantial synchronism with the electrical signals provided by the sensing electrode, the implantable circuit means causing the reconstructive muscle flap to be stimulated to maintain the resting motor tone.

Claim 40

Laryngeal pacemaker according to claim 30 wherein the reconstructive muscle is a STRAP muscle.

Claim 41

Laryngeal pacemaker according to claim 31 wherein the STRAP muscle is one of an omohyoid, a sternohyoid, a thyrohyoid, or a sternothyroid.

Claim 42

Laryngeal pacemaker according to claim 30 wherein the normally functioning intrinsic muscle of the larynx is a cricoarytenoid.

Claim 43

Laryngeal pacemaker according to claim 30 wherein the processing means comprises: a) first means for providing an indication of the level of the electrical signal provided on the sensing electrode; and b) second means operatively coupled to and responsive to the first means for generating the stimulating signals.

Claim 44

Laryngeal pacemaker according to claim 34 wherein the stimulating signals are biphasic D.C. current pulses.

Claim 45

Laryngeal pacemaker according to claim 35 wherein the current pulses have a duration of about 1 m-sec. and a magnitude in the range of about 0.5 mA to 5.0 mA.

Claim 46

Laryngeal pacing method comprising the steps of: a) sensing the level of electrical activity of a resting normally functioning intrinsic laryngeal muscle; b) artificially stimulating a reconstructive muscle flap continuously to preserve resting motor tone.

Claim 47

Laryngeal pacing method comprising the steps of: a) sensing the level of electrical activity of a resting normally functioning intrinsic laryngeal muscle; b) artificially stimulating a reconstructive muscle flap continuously to preserve resting motor tone.