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US5108359A Expired / Lapsed US ⏱️ 0.0 years remaining

Hemangioma treatment method

Assignee: Ferrotherm International Inc
•
Filing: 1990-12-17
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Granted: 1992-04-28
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Expires: 2010-12-17
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Abstract

Abstract The subject of this invention is in the field of medicine, particularly surgery, and is intended for the treatment of benign tumors and angiomas. A hemangioma is an angioma, or tumor, formed by an anomalous proliferation of vascular endothelium, forming an undesirable mass, which can occur anywhere in the body. The resulting disease is known as hemangiomatosis. The method of this invention is comprised of a reduction of the arterial blood flow to the hemangioma which limits the blood circulation in the tumor mass, thus creating favorable conditions for subsequent ferromagnetic embolization from externally and selectively applied electromagnetic or ultrasound energy and sclerotization of the tumor tissue, preventing the spread of ferromagnetic particles through the vessels and into other organs and systems. At the same time, maintaining the blood flow, though reduced, prevents the development of a total necrosis due to acute impairment of the tumor's blood circulation, which significantly reduces the general toxic effect. The reduced blood stream still leaves the possibility of introducing medication into the tumor, which reduces the possibility of complications during the postembolization period.

Inventors

  • 👤 anatoly M. Granov
  • 👤 Vladimir Y. Derkach
  • 👤 Vladimir N. Polysalov

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 01:35
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/40; A61N1/403

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 94 words
A method of hemangioma treatment comprising: selectively catheterizing a supplying artery of a hemangioma tissue site with a metal spiral Gianturko type catheter; acquiring an ultrasonic image of the hemangioma tissue site via an ultrasonic imaging device; introducing a hard ferromagnetic substance into the hemangioma tissue site via said catheter until said substance fills not more than thirty percent of the volume of the hemangioma tissue site, on the basis of said ultrasonic image; applying an electromagnetic field of UHF frequencies to the hemangioma tissue site for a duration of 10 minutes or more.
Claim 2
Independent Claim 94 words
A method of hemangioma treatment comprising: selectively catheterizing a supplying artery of a hemangioma tissue site with a metal spiral Gianturko type catheter; acquiring an ultrasonic image of the hemangioma tissue site via an ultrasonic imaging device; introducing a hard ferromagnetic substance into the hemangioma tissue site via said catheter until said substance fills not more than thirty percent of the volume of the hemangioma tissue site, on the basis of said ultrasonic image; applying an electromagnetic field of UHF frequencies to the hemangioma tissue site for a duration of 10 minutes or more.
Claim 3
Dependent Claim 47 words
A method according to claim 1, wherein said hard ferromagnetic substance is barium hexaferrite used in the form of a suspension in 0.9 percent sodium chloride solution, the proportion of the solid barium hexaferrite and liquid sodium chloride solution being in the range of 1:5 to 1:10.
Claim 4
Dependent Claim 37 words
A method according to claim 1, wherein said step of applying an electromagnetic field is performed once or repeatedly until a full hemangioma thrombosis is achieved, said thrombosis thereafter producing a fibrosis of the hemangioma tissue site.
Claim 5
Independent Claim 90 words
A method of hemangioma treatment comprising: selectively catheterizing a supplying artery of a hemangioma tissue site with a metal spiral Gianturko type catheter; acquiring an ultrasonic image of the hemangioma tissue site via an ultrasonic imaging device; introducing a hard ferromagnetic substance into the hemangioma tissue site via said catheter until said substance fills not more than thirty percent of the volume of the hemangioma tissue site, on the basis of said ultrasonic image; applying ultrasonic energy to the hemangioma tissue site for a duration of 10 minutes or more.
Claim 6
Independent Claim 90 words
A method of hemangioma treatment comprising: selectively catheterizing a supplying artery of a hemangioma tissue site with a metal spiral Gianturko type catheter; acquiring an ultrasonic image of the hemangioma tissue site via an ultrasonic imaging device; introducing a hard ferromagnetic substance into the hemangioma tissue site via said catheter until said substance fills not more than thirty percent of the volume of the hemangioma tissue site, on the basis of said ultrasonic image; applying ultrasonic energy to the hemangioma tissue site for a duration of 10 minutes or more.
Claim 7
Dependent Claim 36 words
A method according to claim 4, wherein said step of applying ultrasonic energy is performed once or repeatedly until a full hemangioma thrombosis is achieved, said thrombosis thereafter producing a fibrosis of the hemangioma tissue site.
Claim 8
Dependent Claim 47 words
A method according to claim 4, wherein said hard ferromagnetic substance is barium hexaferrite used in the form of a suspension in 0.9 percent sodium chloride solution, the proportion of the solid barium hexaferrite and liquid sodium chloride solution being in the range of 1:5 to 1:10.

References Cited (Backward Citations)

US4323056A Cited
US4574782A Cited
US4622952A Cited
US4545368A Cited
US4735796A Cited
US4983159A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-04-28 1995-10-28 1996-04-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-04-28 1999-10-28 2000-04-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-04-28 2003-10-28 2004-04-28 $7700.00 Window Closed / Lapsed

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