Excitatory amino acid antagonists, compositions and use

Claim 1

A compound of the formula: ##STR4## in which T is represented by a C 1-4 alkylene; Z is represented by H, C 1-4 alkyl, phenyl, substituted phenyl, or an alkylphenyl substituent in which the phenyl ring may be optionally substituted; X and Y are each independently represented by a halogen atom; R and R 1 are each independently represented by --OR 2 , --NR 3 R 4 , --OCH 2 OR 2 or --O--(CH 2 ) p --NR 5 R 6 ; R 2 is represented by hydrogen, C 1-4 alkyl, phenyl, substituted phenyl or an alkylphenyl substituent in which the phenyl ring may be optionally substituted; R 3 and R 4 are each independently represented by hydrogen Or a C 1-4 alkyl; p is represented by an integer from 1-4; R 5 and R 6 are each independently represented by a C 1-4 alkyl or together with the adjacent nitrogen atom for a piperidino, morphilino, or pyrrolidinyl group; and the pharmaceutically acceptable addition salts thereof; with the proviso that at least one of R 1 or R must be represented by --O--(CH 2 ) p --NR 5 R 6 .