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US5104875A Expired / Lapsed US ⏱️ 0.0 years remaining

Combination preparations containing rifampicin and thioacetazon

Assignee: FATOL ARZNEIMITTEL ROBERT-KOCH-STRASSE D-6658 SCHIFFWEILER GmbH
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Filing: 1990-05-15
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Granted: 1992-04-14
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Expires: 2010-05-15
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Abstract

Abstract Pharmaceutical combination preparations containing rifampicin and thioacetazon and optionally isonicotinic acid hydrazide or ethambutol and the use of same for the treatment of mycobacterial infections.

Inventors

  • 👤 Klaus Jurgen
  • 👤 Joachim Seydel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 19:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 41 words
A pharmaceutical combination in orally administrable form for the treatment of mycobacterial infections consisting essentially of effective amounts of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2.
Claim 2
Dependent Claim 41 words
A pharmaceutical combination in orally administrable form for the treatment of mycobacterial infections consisting essentially of effective amounts of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2.
Claim 3
Dependent Claim 23 words
The pharmaceutical combination of claim 1, containing from about 300 to about 700 mg rifampicin and from about 50 to about 100 thioacetazon.
Claim 4
Dependent Claim 16 words
The pharmaceutical combination of claim 2, containing about 400 mg rifampicin and about 75 mg thioacetazon.
Claim 5
Dependent Claim 47 words
A pharmaceutical composition in orally administrable form for the treatment of mycobacterial infections consisting essentially of effective amounts of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2; together with a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim 47 words
A pharmaceutical composition in orally administrable form for the treatment of mycobacterial infections consisting essentially of effective amounts of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2; together with a pharmaceutically acceptable carrier.
Claim 7
Independent Claim 42 words
A method treating a mycobacterial infection comprising orally administering to a patient having same, an effective amount, in combination, of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2.
Claim 8
Independent Claim 42 words
A method treating a mycobacterial infection comprising orally administering to a patient having same, an effective amount, in combination, of rifampicin and thioacetazon as the active ingredients in a synergistic weight ratio of rifampicin to thioacetazon of 2 to 6:0.5 to 2.
Claim 9
Dependent Claim 18 words
The method of claim 5, in which the infection is caused by a mycobacteria of the MOTT complex.
Claim 10
Dependent Claim 18 words
The method of claim 5, in which the infection is caused by a mycobacteria of the avium species.

References Cited (Backward Citations)

US3751567A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-04-14 1995-10-14 1996-04-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-04-14 1999-10-14 2000-04-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-04-14 2003-10-14 2004-04-14 $7700.00 Window Closed / Lapsed

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