US5093338A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Lipophilic macrolide useful as an immunosuppressant
Assignee: Merck and Co Inc
•
Filing: 1991-04-23
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Granted: 1992-03-03
•
Expires: 2011-04-23
Abstract
Abstract Disclosed is a novel lipophilic macrolide of Formula I: ##STR1## The compound of assigned Formula I is an analog of rapamycin which has activity as an antifungal agent and as an immunosuppressant.
Inventors
- 👤 Kevin Byrne
- 👤 Robert T. Goegelman
- 👤 Otto Hensens
- 👤 Louis Kaplan
- 👤 Jerrold M. Liesch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 15:32
CPC Classifications
C; C07; C07D; C07D498/00; C07D498/12; C07D498/18; A; A61; A61P; A61P31/00; A61P31/04; A61P37/00; A61P37/02; A61P37/06; C12; C12P; C12P17/00; C12P17/18; C12P17/188
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
18 words
A compound of assigned Formula I, which compound is 7,29-desmethyl rapamycin ##STR5## or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
18 words
A compound of assigned Formula I, which compound is 7,29-desmethyl rapamycin ##STR5## or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
31 words
A pharmaceutical compositions for inducing immunosuppression in a subject in need of such treatment, comprising: a non-toxic therapeutically effective amount of compound according to claim 1 and a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
29 words
A method of inducing immunosuppresion in a subject in need of such treatment comprising: administration to said subject a non-toxic therapeutically effective amount of compound according to claim 1.
References Cited (Backward Citations)
US5023263A
Cited
US5023262A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-03-03 | 1995-09-02 | 1996-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-03-03 | 1999-09-02 | 2000-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-03-03 | 2003-09-02 | 2004-03-03 | $7700.00 | Window Closed / Lapsed |