Transdermal drug patch with conductive fibers

Claim 2

A transdermal drug patch for delivery of at least one drug to a living body through the skin into the bloodstream comprising: at least two electrodes separated from each other; drug reservoir means electrically connected to at least one of said electrodes of said patch for containing the at least one drug, said reservoir means including a medicament-transfer zone for placement at the skin; circuit means, including an electrical power source for supplying electric power to said electrodes and said reservoir means; cover means partially enclosing at least said reservoir means; adhesive means in juxtaposition to said reservoir means for affixing said patch to the skin, whereby when said patch is affixed to the skin the at least one drug is delivered to the skin; and a plurality of electrically conductive fiber means connected with said circuit means and traversing said reservoir means for imposing electrical potential between said at least one of said electrodes and the skin so as to substantially bypass the at least one medicament contained in said reservoir means, wherein said electrically conductive fibers bring the electrical potential more directly to the skin where the drug delivery takes place; and aid in reinforcing the drug patch construction.

Claim 3

A transdermal drug patch as in claim 1, wherein said electrodes are generally of the same construction.

Claim 4

A transdermal drug patch as in claim 1, wherein said electrodes are of differing constructions.

Claim 5

A transdermal drug patch as in claim 1, wherein the electrodes are of different size.

Claim 6

A transdermal drug applicator according to claim 1, wherein said drug reservoir means contain different drugs.

Claim 7

The transdermal drug patch as in claim 1, wherein said fiber means are elongated in shape.

Claim 8

The transdermal drug patch as in claim 1, wherein said fiber means are shaped in a tapered conical configuration having a base and an apex.

Claim 9

The transdermal drug patch as in claim 1, wherein the drug reservoir means contains fiber means extending between at least one electrode and a point near the medicament transfer zone.

Claim 10

The transdermal drug patch as in claim 1, further including a semipermeable membrane coextensive and covering the medicament zone of said drug patch.

Claim 11

The transdermal drug patch as in claim 1, wherein the conductive fiber means are made of carbon.

Claim 12

The transdermal drug patch as in claim 1, wherein the conductive fiber means are made of graphite.

Claim 13

The transdermal drug patch as in claim 1, wherein the conductive fiber means are made of a conductive plastic comprising carbon.

Claim 14

The transdermal drug patch as in claim 1, wherein the drug reservoir means is flexible.

Claim 15

The transdermal drug patch as in claim 1, wherein the electrodes are flexible.

Claim 16

The transdermal drug patch as in claim 1, wherein the cover means is flexible.

Claim 17

A transdermal drug patch for delivery of at least one drug to a living body through the skin into the bloodstream comprising: at least two electrodes separated from each other; drug reservoir means electrically connected to at least one of said electrodes of said patch for containing the at least one drug, said reservoir means including a medicament-transfer zone for placement at the skin; circuit means including an electrical power source for supplying electric power to said electrodes and said reservoir means; cover means partially enclosing at least said reservoir means; adhesive means in juxtaposition to said reservoir means for affixing said patch to the skin, whereby when said patch is affixed to the skin, the at least one drug is delivered to the skin; and a plurality of electrically conductive fibers connected with said circuit means and traversing said reservoir means for imposing electrical potential between said at least one of said electrodes and the skin so as to substantially bypass the at least one medicament contained in said reservoir means, wherein said electrically conductive fibers bring the electrical potential more directly to the skin where the drug delivery takes place; and wherein the drug-reservior means includes a high concentration drug zone containing a high concentration of the at least one drug and a low concentration drug zone containing a low concentration of the at least one drug and a semipermeable membrane positioned between the low and high concentration drug zones, with said high concentration drug located between at least one electrode and said membrane.

Claim 18

A transdermal drug patch for delivery of at least one drug to a living body through the skin into the bloodstream comprising: at least two electrodes separated from each other; drug reservoir means electrically connected to at least one of said electrodes of said patch for containing the at least one drug, said reservoir means including a medicament-transfer zone for placement at the skin; circuit means including an electrical power source for supplying electric power to said electrodes and said reservoir means; cover means partially enclosing at least said reservoir means; adhesive means in juxtaposition to said reservoir means for affixing said patch to the skin, whereby when said patch is affixed to the skin, the at least one drug is delivered to the skin; and a plurality of electrically conductive fibers connected with said circuit means and traversing said reservoir means for imposing electrical potential between said at least one of said electrodes and the skin so as to substantially bypass the at least one medicament contained in said reservoir means, wherein said electrically conductive fibers bring the electrical potential more directly to the skin where the drug delivery takes place; and wherein the drug-reservior means includes a high concentration drug zone containing a high concentration of the at least one drug and a low concentration drug zone containing a low concentration of the at least one drug and a semipermeable membrane positioned between the low and high concentration drug zones, with said high concentration drug located between at least one electrode and said membrane.

Claim 19

The transdermal drug patch as in claim 16, wherein the fibers traverse at least one of said drug zones.

Claim 20

The transdermal drug patch as in claim 17, wherein the conductive fibers traverse both the high concentration drug zone and the low concentration drug zone and extend from at least one electrode.

Claim 21

The transdermal drug patch as in claim 16, wherein the conductive fibers include a first group which traverse the high concentration drug zone and a second group which traverse the low concentration drug zone.

Claim 22

A transdermal drug patch for delivery of at least one drug to a living body through the skin into the bloodstream comprising: at least two electrodes separated from each other; drug reservoir means electrically connected to at least one of said electrodes of said patch for containing the at least one drug, said reservoir means including a medicament-transfer zone for placement at the skin; circuit means, including an electrical power source for supplying electric power to said electrodes and said reservoir means; cover means partially enclosing at least said reservoir means; adhesive means in juxtaposition to said reservoir means for affixing said patch to the skin, whereby when said patch is affixed to the skin, the at least one drug is delivered to the skin; and a plurality of electrically conductive fibers connected with said circuit means and traversing said reservoir means for imposing electrical potential between said at least one said electrodes and the skin so as to substantially bypass the at least one medicament contained in said reservoir means, wherein said electrically conductive fibers bring the electrical potential more directly to the skin medicament-transfer zone where the drug delivery takes place; and including a semipermeable membrane coextensive with and covering medicament-transfer zone of said patch, said semipermeable membrane comprising a microporous adhesive material.

Claim 23

A transdermal drug patch for delivery of at least one drug to a living body through the skin into the bloodstream comprising: at least two electrodes separated from each other; drug reservoir means electrically connected to at least one of said electrodes of said patch for containing the at least one drug, said reservoir means including a medicament-transfer zone for placement at the skin; circuit means, including an electrical power source for supplying electric power to said electrodes and said reservoir means; cover means partially enclosing at least said reservoir means; adhesive means in juxtaposition to said reservoir means for affixing said patch to the skin, whereby when said patch is affixed to the skin, the at least one drug is delivered to the skin; and a plurality of electrically conductive fibers connected with said circuit means and traversing said reservoir means for imposing electrical potential between said at least one said electrodes and the skin so as to substantially bypass the at least one medicament contained in said reservoir means, wherein said electrically conductive fibers bring the electrical potential more directly to the skin medicament-transfer zone where the drug delivery takes place; and including a semipermeable membrane coextensive with and covering medicament-transfer zone of said patch, said semipermeable membrane comprising a microporous adhesive material.