US5086275A — Time domain filtering for nmr phased array imaging

Claim 1

Independent Claim 179 words

A method for combining NMR response data of a sample from a plurality of RF receiver coils of an NMR phased array in the time domain to form a composite NMR image, comprising the steps of: (a) receiving at each of the RF receiver coils a different one of a plurality of NMR response signals, each of the signals being evoked from a portion of the sample within a field of view of a respective one of the receiver coils; (b) conditioning each of the response signals develop a plurality of data point signals corresponding to the magnitude of each of the respective response signals from each of the receiver coils at successive time intervals; (c) convolving each of the data point signals by a time domain representation of a field map of the respective one of the receiver coils generating the corresponding one of the response signals; and (d) combining the signals obtained by the step of convolving on a time domain point-by-point basis to produce a time domain representation of the composite NMR image of the sample.

Claim 2

Independent Claim 179 words

A method for combining NMR response data of a sample from a plurality of RF receiver coils of an NMR phased array in the time domain to form a composite NMR image, comprising the steps of: (a) receiving at each of the RF receiver coils a different one of a plurality of NMR response signals, each of the signals being evoked from a portion of the sample within a field of view of a respective one of the receiver coils; (b) conditioning each of the response signals develop a plurality of data point signals corresponding to the magnitude of each of the respective response signals from each of the receiver coils at successive time intervals; (c) convolving each of the data point signals by a time domain representation of a field map of the respective one of the receiver coils generating the corresponding one of the response signals; and (d) combining the signals obtained by the step of convolving on a time domain point-by-point basis to produce a time domain representation of the composite NMR image of the sample.

Claim 3

Dependent Claim 15 words

The method of claim 1 wherein adjacent ones of the response coils have overlapping fields-of-view.

Claim 4

Dependent Claim 13 words

The method of claim 2 wherein the response coils have substantially zero interaction.

Claim 5

Dependent Claim 30 words

The method of claim 1 wherein the step of receiving includes the step of detecting each of the response signals from each respective one of the receiver coils substantially simultaneously.

Claim 6

Dependent Claim 35 words

The method of claim 1 wherein the step of conditioning includes the step of digitizing each of the response signals to form a plurality of different series of discrete ones of the data point signals.

Claim 7

Dependent Claim 24 words

The method of claim 5 wherein the step of convolving includes the step of reducing each time domain representation to a central kernel size.

Claim 8

Dependent Claim 18 words

The method of claim 6 wherein the step of convolving is performed in accordance with the relationship: ##EQU6##

Claim 9

Dependent Claim 46 words

The method of claim 1 wherein the step of convolving includes the steps of obtaining an initial NMR image representation of the sample from each of the RF receiver coils and substituting the initial NMR image representation for the time domain representation of each receiver coil.

Claim 10

Dependent Claim 17 words

The method of claim 1 wherein the NMR composite image comprises a spectroscopic image of the sample.

Claim 11

Independent Claim 202 words

A method for combining NMR response data from receiver coils of an NMR phased array in the time domain using filtering to form a composite NMR image having good overall SNR resolution, comprising the steps of: (a) providing a plurality of closely-spaced RF receiver coils, with adjacent coils having overlapping fields-of-view and substantially no interaction; (b) substantially simultaneously receiving at each one of the coils a different one of a plurality of NMR response signals, each evoked from a portion of the sample within the field-of-view of that coil; (c) digitizing the response signal of each coil to provide a plurality of different series of discrete data point signals corresponding to the magnitudes of the response at successive time intervals for each coil; (d) temporarily storing an m×1 number of said data point signals of each of the series of signals; (e) multiplying the temporarily stored signals by a corresponding m×1 number of signals digitized time domain representation of a field map of the coil associated with the series reduced to a central m×1 kernel size; and (f) combining the multiplied temporarily stored signals of each coil, on a time domain point-by-point basis, to produce a composite NMR image of the sample.

Claim 12

Independent Claim 202 words

A method for combining NMR response data from receiver coils of an NMR phased array in the time domain using filtering to form a composite NMR image having good overall SNR resolution, comprising the steps of: (a) providing a plurality of closely-spaced RF receiver coils, with adjacent coils having overlapping fields-of-view and substantially no interaction; (b) substantially simultaneously receiving at each one of the coils a different one of a plurality of NMR response signals, each evoked from a portion of the sample within the field-of-view of that coil; (c) digitizing the response signal of each coil to provide a plurality of different series of discrete data point signals corresponding to the magnitudes of the response at successive time intervals for each coil; (d) temporarily storing an m×1 number of said data point signals of each of the series of signals; (e) multiplying the temporarily stored signals by a corresponding m×1 number of signals digitized time domain representation of a field map of the coil associated with the series reduced to a central m×1 kernel size; and (f) combining the multiplied temporarily stored signals of each coil, on a time domain point-by-point basis, to produce a composite NMR image of the sample.

Claim 13

Dependent Claim 225 words

Apparatus for receiving and combining NMR response data from a plurality of RF receiver coils of an NMR phased array to form a composite NMR image of a sample, comprising: a plurality of receiver circuits each connected to a respective one of the coils for receiving a corresponding NMR response signal, each response signal being evoked from a portion of the sample within the field-of-view of the response one of the coils; an analog-to-digital converter connected to each receiver circuit for providing a series of discrete digital signals corresponding to a succession of time space data points representative of the response signals from each one of the coils; means associated with each coil for providing an m×1 number of digitized signals corresponding to the digitized time domain representation of a field map of the associated coil reduced to a central m×1 kernel size; means connected to each converter and to said means associated with each coil for temporarily storing each last m×1 number of said series of discrete digital signals; means for convolving each series of discrete digital signals with said digitized signals of said time domain representation of each field map to provide a convolved signal series; and means connected to said temporary storing means for combining said convolved series to provide a time domain representation of a composite NMR image of the sample.

Claim 14

Dependent Claim 225 words

Apparatus for receiving and combining NMR response data from a plurality of RF receiver coils of an NMR phased array to form a composite NMR image of a sample, comprising: a plurality of receiver circuits each connected to a respective one of the coils for receiving a corresponding NMR response signal, each response signal being evoked from a portion of the sample within the field-of-view of the response one of the coils; an analog-to-digital converter connected to each receiver circuit for providing a series of discrete digital signals corresponding to a succession of time space data points representative of the response signals from each one of the coils; means associated with each coil for providing an m×1 number of digitized signals corresponding to the digitized time domain representation of a field map of the associated coil reduced to a central m×1 kernel size; means connected to each converter and to said means associated with each coil for temporarily storing each last m×1 number of said series of discrete digital signals; means for convolving each series of discrete digital signals with said digitized signals of said time domain representation of each field map to provide a convolved signal series; and means connected to said temporary storing means for combining said convolved series to provide a time domain representation of a composite NMR image of the sample.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1995-02-03	1995-08-05	1996-02-04	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1999-02-03	1999-08-05	2000-02-04	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	2003-02-03	2003-08-05	2004-02-04	$7700.00	Window Closed / Lapsed

Time domain filtering for nmr phased array imaging

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