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US5070107A Expired / Lapsed US ⏱️ 0.0 years remaining

Systemic antiviral treatment

Assignee: Avanir Pharmaceuticals Inc
•
Filing: 1989-11-02
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Granted: 1991-12-03
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Expires: 2009-11-02
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Abstract

Abstract Systemic antiviral treatment using a narrow class of aliphatic straight-chain saturated monohydric alcohols which have from 27 to 32 carbons in the chain in physiologically compatible compositions for injection or trans-mucus membrance introduction into humans and other mammals is disclosed.

Inventors

  • 👤 David H. Katz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 15:28
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/045; A61P; A61P31/00; A61P31/12

Claims Analysis

Total Claims: 26
Claim 1
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising intravenous introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 2
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising intravenous introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 3
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising intramuscular introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 4
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising intramuscular introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 5
Independent Claim 64 words
A method of treating humans or other mammals for viral infections, comprising trans-mucus membranal introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 6
Independent Claim 64 words
A method of treating humans or other mammals for viral infections, comprising trans-mucus membranal introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 7
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising transdermal penetration into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 8
Independent Claim 63 words
A method of treating humans or other mammals for viral infections, comprising transdermal penetration into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 9
Independent Claim 68 words
A method of preventing or inhibiting the infection of humans or other mammals for viral infections, comprising intravenous introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 10
Independent Claim 68 words
A method of preventing or inhibiting the infection of humans or other mammals for viral infections, comprising intravenous introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 11
Independent Claim 68 words
A method of preventing or inhibiting the infection of humans or other mammals for viral infections, comprising intramuscular introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 12
Independent Claim 68 words
A method of preventing or inhibiting the infection of humans or other mammals for viral infections, comprising intramuscular introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 13
Independent Claim 66 words
A method of preventing or inhibiting the infection of humans or other mammals, comprising trans-mucus membranal introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 14
Independent Claim 66 words
A method of preventing or inhibiting the infection of humans or other mammals, comprising trans-mucus membranal introduction into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 15
Independent Claim 65 words
A method of preventing or inhibiting the infection of humans or other mammals, comprising transdermal penetration into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 16
Independent Claim 65 words
A method of preventing or inhibiting the infection of humans or other mammals, comprising transdermal penetration into the human or other mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible carrier.
Claim 17
Dependent Claim 43 words
A physiologically compatible solution which can be injected into humans or other mammals for viral infections intravenously or intramuscularly consisting essentially of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible, intravenously or intramuscularly injectable carrier.
Claim 18
Dependent Claim 43 words
A physiologically compatible solution which can be injected into humans or other mammals for viral infections intravenously or intramuscularly consisting essentially of a composition consisting of one or more C-27 to C-32 aliphatic alcohols in a physiologically compatible, intravenously or intramuscularly injectable carrier.
Claim 19
Dependent Claim 38 words
A physiologically compatible transdermal medication for introduction through the mucous membranes into humans or other mammals for viral infections consisting essentially of a composition consisting of one or more C-27 to C-32 aliphatic alcohols and a penetration-enhancing compound.
Claim 20
Dependent Claim 38 words
A physiologically compatible transdermal medication for introduction through the mucous membranes into humans or other mammals for viral infections consisting essentially of a composition consisting of one or more C-27 to C-32 aliphatic alcohols and a penetration-enhancing compound.
Claim 21
Independent Claim 43 words
A method of preventing conception and reducing the risk of viral infection comprising introducing a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons in a suitable carrier into the vagina substantially contemporaneously with or before intercourse.
Claim 22
Independent Claim 43 words
A method of preventing conception and reducing the risk of viral infection comprising introducing a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons in a suitable carrier into the vagina substantially contemporaneously with or before intercourse.
Claim 23
Dependent Claim 54 words
An anti-viral suppository for trans-membranal introduction into the vagina or anus of a human or other mammal of a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons in a physiologically acceptable carrier which is a solid at ambient room temperature and which melts at approximately 37° C.
Claim 24
Dependent Claim 54 words
An anti-viral suppository for trans-membranal introduction into the vagina or anus of a human or other mammal of a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons in a physiologically acceptable carrier which is a solid at ambient room temperature and which melts at approximately 37° C.
Claim 25
Independent Claim 93 words
A method of treating humans and mammals for viral infections comprising introducing a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons through a membrane into the circulatory system of a human or mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight comprising inserting such alcohol composition in a physiologically acceptable liquid, cream, gel or suppository carrier into the anus or vagina of the human or mammal to be treated.
Claim 26
Independent Claim 93 words
A method of treating humans and mammals for viral infections comprising introducing a composition consisting essentially of one or more aliphatic alcohols having from 27 to 32 carbons through a membrane into the circulatory system of a human or mammal suspected of having a viral infection with an effective amount of from about 0.1 mg to about 2 gm per 50 kg of body weight comprising inserting such alcohol composition in a physiologically acceptable liquid, cream, gel or suppository carrier into the anus or vagina of the human or mammal to be treated.

References Cited (Backward Citations)

US4186211A Cited
FR2569108A1 Cited
US4513008A Cited
WO1988007866A1 Cited
WO1990004388A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-12-02 1995-06-03 1995-12-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-12-02 1999-06-03 1999-12-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-12-02 2003-06-03 2003-12-03 $7700.00 Window Closed / Lapsed

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