US5064413A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Needleless hypodermic injection device
Assignee: Bioject Inc
•
Filing: 1989-11-09
•
Granted: 1991-11-12
•
Expires: 2009-11-09
Abstract
Abstract A needleless injection device has a housing containing a pilot valve connectable to a compressed gas source. A main valve is operatively connected to the pilot valve. The pilot valve and main valve form a two-stage valve with the pilot valve activatable to open the main valve utilizing gas pressure. Compressed gas in a reservoir flows through the open main valve to driven a plunger into an ampule to inject an injectant through a patient's skin.
Inventors
- 👤 Charles M. McKinnon
- 👤 Takaaki Nakagawa
- 👤 Carl E. Wilcox
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 18:13
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/178; A61M5/30; A61M2205/00; A61M2205/58; A61M2205/583; A61M5/20; A61M5/2053; A61M5/48; A61M5/486
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
70 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; and a main valve having a substantially unbiased main valve piston, said main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver.
Claim 2
Dependent Claim
70 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; and a main valve having a substantially unbiased main valve piston, said main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver.
Claim 3
Dependent Claim
40 words
The injection device of claim 1 further comprising: a cartridge holder attachable to said housing and having a cartridge chamber; a valve body disposed within said housing; and a gas delivery tube connecting said cartridge chamber and said valve body.
Claim 4
Dependent Claim
22 words
The injection device of claim 2 further comprising a piercing body spaced apart from said valve body and forming a reservoir therebetween.
Claim 5
Dependent Claim
17 words
The injection device of claim 2 further comprising a gas filter associated with said gas delivery tube.
Claim 6
Dependent Claim
18 words
The injection device of claim 2 further comprising at least one bleed hole in said gas delivery tube.
Claim 7
Dependent Claim
32 words
The injection device of claim 1 further comprising a liner having a liner seat, and a main valve piston with said main valve piston and said liner seat comprising said main valve.
Claim 8
Dependent Claim
42 words
The injection device of claim 3 wherein at least said liner and said main valve piston form an annular chamber between said liner and said main valve piston with said annular chamber connected by at least one gas passageway to said reservoir.
Claim 9
Dependent Claim
17 words
The injection device of claim 7 wherein said gas passageway comprises a slot on said valve body.
Claim 10
Dependent Claim
19 words
The injection device of claim 6 wherein said main valve piston has a sealing face including an elastomeric seal.
Claim 11
Dependent Claim
15 words
The injection device of claim 1 wherein said pilot valve comprises a Schrader-type poppet valve.
Claim 12
Dependent Claim
128 words
An injection device comprising: a housing; a plunger driver within said housing; a valve body within said housing; a pilot valve within a pilot valve chamber in said valve body; a main valve having a main valve seat within said housing and a substantially unbiased main valve piston sealingly engageable to said main valve seat; a gas delivery tube connectable to a compressed gas source and joined to said pilot valve chamber and said main piston chamber, said gas delivery tube having a bleed hole leading to a reservoir; said pilot valve activatable to create a gas pressure difference on opposite sides of said main valve causing it to separate from said valve seat such that compressed gas in said reservoir is released to drive said plunger driver.
Claim 13
Dependent Claim
128 words
An injection device comprising: a housing; a plunger driver within said housing; a valve body within said housing; a pilot valve within a pilot valve chamber in said valve body; a main valve having a main valve seat within said housing and a substantially unbiased main valve piston sealingly engageable to said main valve seat; a gas delivery tube connectable to a compressed gas source and joined to said pilot valve chamber and said main piston chamber, said gas delivery tube having a bleed hole leading to a reservoir; said pilot valve activatable to create a gas pressure difference on opposite sides of said main valve causing it to separate from said valve seat such that compressed gas in said reservoir is released to drive said plunger driver.
Claim 14
Dependent Claim
194 words
An injection device comprising: a housing; a plunger driver slidably positioned within said housing; a piercing body within said housing; a valve body in said housing spaced apart from said piercing body; a gas delivery tube extending from said piercing body to said valve body; a reservoir formed at least by said valve body and said housing, said gas delivery tube having a bleed hole opening to said reservoir; a pilot valve substantially disposed in a pilot valve chamber in said valve body; a main valve seat; a main valve piston slidably disposed within said housing and sealingly engageable against said main valve seat; said main valve piston having a first chamber on a first side thereof, said first chamber connected to said reservoir via a gas passageway, said main valve piston having a second chamber on a second side thereof, said second chamber connecting to said pilot valve chamber; said pilot valve activatable to vent said pilot valve chamber thereby causing said main valve piston separate from said main valve seat such that compressed gas from said reservoir flows past said main valve piston into a plunger chamber to drive said plunger driver.
Claim 15
Dependent Claim
194 words
An injection device comprising: a housing; a plunger driver slidably positioned within said housing; a piercing body within said housing; a valve body in said housing spaced apart from said piercing body; a gas delivery tube extending from said piercing body to said valve body; a reservoir formed at least by said valve body and said housing, said gas delivery tube having a bleed hole opening to said reservoir; a pilot valve substantially disposed in a pilot valve chamber in said valve body; a main valve seat; a main valve piston slidably disposed within said housing and sealingly engageable against said main valve seat; said main valve piston having a first chamber on a first side thereof, said first chamber connected to said reservoir via a gas passageway, said main valve piston having a second chamber on a second side thereof, said second chamber connecting to said pilot valve chamber; said pilot valve activatable to vent said pilot valve chamber thereby causing said main valve piston separate from said main valve seat such that compressed gas from said reservoir flows past said main valve piston into a plunger chamber to drive said plunger driver.
Claim 16
Dependent Claim
26 words
The injection device of claim 12 further comprising a sleeve section on said valve body with said main valve piston slidably displaceable within said sleeve section.
Claim 17
Dependent Claim
61 words
An injection method comprising the steps of: positioning a nozzle of an injection device onto an injection site; activating a biased pilot valve of the device; and allowing an unbiased main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle.
Claim 18
Dependent Claim
61 words
An injection method comprising the steps of: positioning a nozzle of an injection device onto an injection site; activating a biased pilot valve of the device; and allowing an unbiased main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle.
Claim 19
Dependent Claim
17 words
The method of claim 14 further comprising the step of supplying compressed gas to the pilot valve.
Claim 20
Dependent Claim
28 words
The method of claim 15 further comprising the step of supplying compressed gas from the reservoir around the pilot valve to the main valve via a gas passageway.
Claim 21
Dependent Claim
16 words
The method of claim 14 further comprising the step of supplying compressed gas to a reservoir.
Claim 22
Dependent Claim
30 words
The method of claim 14 wherein compressed gas is supplied to the pilot valve by connecting a compressed gas cartridge to a gas delivery tube leading to the pilot valve.
Claim 23
Dependent Claim
20 words
The method of claim 18 further comprising the step of bleeding gas from the gas delivery tube to the reservoir.
Claim 24
Dependent Claim
25 words
The method of claim 14 further comprising the step of metering the compressed gas supplied to the pilot valve by passing it through an orifice.
Claim 25
Dependent Claim
39 words
The method of claim 14 wherein said nozzle is on an ampule releasably attached to the injection device, further comprising the step of using the compressed gas flowing by the main valve to drive a plunger into the ampule.
Claim 26
Independent Claim
102 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; placing the nozzle of the ampule onto an injection site; activating a biased pilot valve to vent a pilot valve chamber; opening an unbiased main valve with a gas pressure difference across opposite sides of the main valve resulting from activation of the pilot valve; and driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve to drive the injectant out of the ampule through the nozzle.
Claim 27
Independent Claim
102 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; placing the nozzle of the ampule onto an injection site; activating a biased pilot valve to vent a pilot valve chamber; opening an unbiased main valve with a gas pressure difference across opposite sides of the main valve resulting from activation of the pilot valve; and driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve to drive the injectant out of the ampule through the nozzle.
Claim 28
Dependent Claim
26 words
The method of claim 22 further comprising the step of connecting a compressed gas source to the pilot valve chamber, a reservoir and a seat chamber.
Claim 29
Dependent Claim
76 words
An injection device assembly comprising: a device housing; a pilot valve within said device housing connectable to a compressed gas source; an ampule for holding an injectant, said ampule having a nozzle, and said ampule attachable to said device housing; an unbiased main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive an injectant from said nozzle.
Claim 30
Dependent Claim
76 words
An injection device assembly comprising: a device housing; a pilot valve within said device housing connectable to a compressed gas source; an ampule for holding an injectant, said ampule having a nozzle, and said ampule attachable to said device housing; an unbiased main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive an injectant from said nozzle.
Claim 31
Dependent Claim
118 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; a main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver; a cartridge holder attachable to said housing and having a cartridge chamber; a valve body disposed within said housing; a gas delivery tube connecting said cartridge chamber and said valve body; a piercing body spaced apart from said valve body and forming a reservoir therebetween; and a spacer disposed within said reservoir to limit the volume of said reservoir.
Claim 32
Dependent Claim
118 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; a main valve operatively connected to said pilot valve, said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver; a cartridge holder attachable to said housing and having a cartridge chamber; a valve body disposed within said housing; a gas delivery tube connecting said cartridge chamber and said valve body; a piercing body spaced apart from said valve body and forming a reservoir therebetween; and a spacer disposed within said reservoir to limit the volume of said reservoir.
Claim 33
Dependent Claim
86 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; a liner having a liner sheet; a main valve piston having a central counterbore, said main valve piston and said liner seat comprising a main valve; said main valve operatively connected to said pilot valve, and said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver.
Claim 34
Dependent Claim
86 words
An injection device comprising: a housing; a plunger driver slidably disposed within said housing; a pilot valve within said housing connectable to a compressed gas source; a liner having a liner sheet; a main valve piston having a central counterbore, said main valve piston and said liner seat comprising a main valve; said main valve operatively connected to said pilot valve, and said pilot valve activatable to open said main valve such that compressed gas may flow by said main valve to drive said plunger driver.
Claim 35
Dependent Claim
71 words
An injection method comprising the steps of: positioning a nozzle of an injection device onto an injection site; activating a pilot valve of the device; allowing a main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle; supplying compressed gas to a reservoir; and adjusting the volume of the reservoir.
Claim 36
Dependent Claim
71 words
An injection method comprising the steps of: positioning a nozzle of an injection device onto an injection site; activating a pilot valve of the device; allowing a main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle; supplying compressed gas to a reservoir; and adjusting the volume of the reservoir.
Claim 37
Dependent Claim
94 words
An injection method comprising the steps of: connecting a compressed gas cartridge to a gas delivery tube leading to the pilot valve, to supply compressed gas to a pilot valve within an injection device; filtering the compressed gas supplied to the delivery tube; positioning a nozzle of the injection device onto an injection site; activating a pilot valve of the device; allowing a main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle;
Claim 38
Dependent Claim
94 words
An injection method comprising the steps of: connecting a compressed gas cartridge to a gas delivery tube leading to the pilot valve, to supply compressed gas to a pilot valve within an injection device; filtering the compressed gas supplied to the delivery tube; positioning a nozzle of the injection device onto an injection site; activating a pilot valve of the device; allowing a main valve of the device to open in response to activation of the pilot valve, thereby allowing compressed gas to pass by the main valve to drive injectant from the nozzle;
Claim 39
Independent Claim
122 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; placing the nozzle of the ampule onto an injection site; activating a pilot valve to vent a pilot valve chamber; opening a main valve with a gas pressure difference across opposite sides of the main valve resulting from activation of the pilot valve; driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve to drive the injectant out of the ampule through the nozzle; releasing the pilot valve and resealing the pilot valve chamber; refilling the pilot valve chamber with compressed gas; and closing the main valve.
Claim 40
Independent Claim
122 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; placing the nozzle of the ampule onto an injection site; activating a pilot valve to vent a pilot valve chamber; opening a main valve with a gas pressure difference across opposite sides of the main valve resulting from activation of the pilot valve; driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve to drive the injectant out of the ampule through the nozzle; releasing the pilot valve and resealing the pilot valve chamber; refilling the pilot valve chamber with compressed gas; and closing the main valve.
Claim 41
Independent Claim
135 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; connecting a compressed gas source to a pilot valve chamber, a reservoir and a seat chamber within the injector; placing the nozzle of the ampule onto an injection site; activating a pilot valve to vent a pilot valve chamber; opening a main valve with a gas pressure difference across opposite sides of the main valve, resulting from activation of the pilot valve; driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve, to drive the injectant out of the ampule through the nozzle; selecting an ampule opening and a spacer for the reservoir for one of intramuscular and subcutaneous injection.
Claim 42
Independent Claim
135 words
A method of intramuscular and subcutaneous injection comprising the steps of: installing an ampule containing an injectant and having a nozzle into a holder on an injector; connecting a compressed gas source to a pilot valve chamber, a reservoir and a seat chamber within the injector; placing the nozzle of the ampule onto an injection site; activating a pilot valve to vent a pilot valve chamber; opening a main valve with a gas pressure difference across opposite sides of the main valve, resulting from activation of the pilot valve; driving a plunger into the ampule with gas pressure developed by compressed gas flowing past the main valve, to drive the injectant out of the ampule through the nozzle; selecting an ampule opening and a spacer for the reservoir for one of intramuscular and subcutaneous injection.
References Cited (Backward Citations)
US2704543A
Cited
US2025219A
Cited
US2605763A
Cited
US2547099A
Cited
US2737946A
Cited
US2653602A
Cited
US2764977A
Cited
US3110309A
Cited
US3292621A
Cited
US3292622A
Cited
US3515130A
Cited
US3561443A
Cited
US3688765A
Cited
US3945379A
Cited
US4059107A
Cited
US4124024A
Cited
US4421508A
Cited
US4507113A
Cited
US4626242A
Cited
US4634027A
Cited
US4596556A
Cited
WO1987003494A1
Cited
US4680027A
Cited
US4790824A
Cited
US4874367A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-11-11 | 1995-05-13 | 1995-11-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-11-11 | 1999-05-13 | 1999-11-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-11-11 | 2003-05-13 | 2003-11-12 | $7700.00 | Window Closed / Lapsed |