US5059619A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stable freeze-dried polyhematoporphyrin ether/ester
Assignee: Aptalis Pharma Canada ULC
•
Filing: 1989-06-14
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Granted: 1991-10-22
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Expires: 2009-06-14
Abstract
Abstract A pharmaceutical composition comprising a freeze-dried preparation of polyhematoporphyrin ether/esters wherein said freeze dried preparation does not contain sodium chloride. Upon reconstitution, the pharmaceutical composition is a photosensitizer preparation useful in photodynamic therapy.
Inventors
- 👤 Bruce E. Haeger
- 👤 James R. Lawter
- 👤 Vijay H. Naringrekar
- 👤 Michael C. Cucolo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 11:19
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61K41/00; A61K41/0057; A61K41/0071; A61K9/00; A61K9/14; A61K9/19; A61P; A61P35/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
19 words
A pharmaceutical composition comprising a freeze-dried preparation of polyhematoporphyrin ether/esters wherein said freeze-dried preparation does not contain sodium chloride.
Claim 2
Dependent Claim
19 words
A pharmaceutical composition comprising a freeze-dried preparation of polyhematoporphyrin ether/esters wherein said freeze-dried preparation does not contain sodium chloride.
Claim 3
Dependent Claim
23 words
A pharmaceutical composition which consists essentially of the freeze-dried composition of claim 1 as active ingredient in association with a pharmaceutically acceptable excipient.
Claim 4
Dependent Claim
18 words
A pharmaceutical composition according to claim 2 in which the pharmaceutically acceptable excipient is a non-electrolyte bulking agent.
Claim 5
Dependent Claim
17 words
A pharmaceutical composition according to claim 3 in which the non-electrolyte bulking agent is mannitol or dextrose.
Claim 6
Dependent Claim
14 words
A freeze-dried pharmaceutical composition according to claim 1 containing less than 1% residual water.
Claim 7
Dependent Claim
18 words
A pharmaceutical composition comprising a freeze dried preparation according to claim 1 reconstituted with 5% dextrose for injection.
References Cited (Backward Citations)
US2858320A
Cited
US4649151A
Cited
US4753958A
Cited
EP0210351A2
Cited
US4882234A
Cited
WO1990000392A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-10-21 | 1995-04-22 | 1995-10-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-10-21 | 1999-04-22 | 1999-10-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-10-21 | 2003-04-22 | 2003-10-22 | $7700.00 | Window Closed / Lapsed |