Abstract This invention relates to superior bioadhesive compositions having time extended adhesive properties comprising a non-toxic carrier and a polymer having between about 45 and about 70 weight % of units having the structure ##STR1## between about 50 and about 30 weight % of units having the structure ##STR2## and 2 and 7 weight % of an amine salt containing a lactam functionality derived from A and/or B, wherein R is hydrogen, alkoxy, phenyl, carboxyl or --N lactam having from 3 to 6 carbon atoms; R 1 is C 1 to C 6 alkylene and R 2 is C 2 to C 4 alkylene; said copolymer having a number average molecular weight of about 40,000 to about 500,000 and a relatively small particle size. The invention also relates to the method of synthesizing and using the above composition.
Inventors
👤 Ratan K. Chaudhuri
👤 Rama K. Haldar
👤 Balgopal Gangadharan
Bibliographic Details
Application Number—
JurisdictionUS
Data Sourcegoogle_patents
Last Synchronized2026-11-05 09:00
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/04; A61L24/06
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
132 words
The process of applying to a device adapted for affixation to a mucous membrane, an effective adhesive amount of the composition comprising a non-toxic carrier and a polymer comprising between about 45 and about 70 weight % of units having the structure ##STR9## between about 50 and about 30 weight % of units having the structure ##STR10## and 2 to 7 weight % of an amine salt containing a lactam functionality derived from A and/or B, wherein R is hydrogen, alkoxy, phenyl, carboxyl or --N lactam having from 3 to 6 carbon atoms; R 1 is C 1 to C 6 alkylene and R 2 is C 2 to C 4 alkylene; said copolymer having a number average molecular weight of about 40,000 to about 500,000 and a relatively small particle size.
Claim 2
Dependent Claim
132 words
The process of applying to a device adapted for affixation to a mucous membrane, an effective adhesive amount of the composition comprising a non-toxic carrier and a polymer comprising between about 45 and about 70 weight % of units having the structure ##STR9## between about 50 and about 30 weight % of units having the structure ##STR10## and 2 to 7 weight % of an amine salt containing a lactam functionality derived from A and/or B, wherein R is hydrogen, alkoxy, phenyl, carboxyl or --N lactam having from 3 to 6 carbon atoms; R 1 is C 1 to C 6 alkylene and R 2 is C 2 to C 4 alkylene; said copolymer having a number average molecular weight of about 40,000 to about 500,000 and a relatively small particle size.
Claim 3
Dependent Claim
19 words
The process of claim 1 wherein an effective amount of said composition is employed for fixation of a denture.
Claim 4
Dependent Claim
19 words
A process for affixing to a mucous membrane having coated on its fixation surface, the composition of claim 1.
Claim 5
Dependent Claim
19 words
The process of claim 3 wherein an effective amount of said composition is employed for fixation of a denture.