US5051370A
Expired / Lapsed
US
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Method for the evaluation of agglutination reactions
Assignee: Hoechst AG
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Filing: 1990-06-11
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Granted: 1991-09-24
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Expires: 2010-06-11
Abstract
Abstract In the method for the evaluation of agglutination reactions between a reagent and a biological fluid to be examined, the reagent and the biological fluid are intimately mixed by agitation with a tumbling motion. The mixture is then placed in the ray path of an optical measuring system and, while maintaining the tumbling motion and superimposing a translational motion at right angles to the optical axis of the measuring system, an image of the agglutinates formed in the mixture is produced on a focusing screen, and the image is evaluated with an evaluation unit.
Inventors
- 👤 Detlef Schulze
- 👤 Rudolf Schmidtberger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 07:23
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/75; G01N21/77; G01N21/82; Y; Y10; Y10S; Y10S436/00; Y10S436/805
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
83 words
A method for the evaluation of agglutination reactions between a reagent and a biological fluid, comprising mixing the reagent and the biological fluid by agitation employing a tumbling motion; placing the mixture in the ray path of an optical measuring system; superimposing a translational motion at right angles to the optical axis of the measuring system while maintaining said tumbling motion; producing on a focusing screen an image of any agglutinates formed in the mixture; and evaluating the image with an evaluation unit.
Claim 2
Independent Claim
83 words
A method for the evaluation of agglutination reactions between a reagent and a biological fluid, comprising mixing the reagent and the biological fluid by agitation employing a tumbling motion; placing the mixture in the ray path of an optical measuring system; superimposing a translational motion at right angles to the optical axis of the measuring system while maintaining said tumbling motion; producing on a focusing screen an image of any agglutinates formed in the mixture; and evaluating the image with an evaluation unit.
Claim 3
Dependent Claim
24 words
A method according to claim 1, wherein said evaluation is a qualitative evaluation of said agglutination reactions between said reagent and said biological fluid.
Claim 4
Dependent Claim
24 words
A method according to claim 1, wherein said evaluation is a quantitative evaluation of said agglutination reactions between said reagent and said biological fluid.
Claim 5
Dependent Claim
28 words
A method according to claim 3, wherein said quantitative evaluation is the determination of the concentration of the agglutinates formed and said quantitative evaluation employs a calibration plot.
References Cited (Backward Citations)
US3997272A
Cited
US4400353A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-09-23 | 1995-03-25 | 1995-09-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-09-23 | 1999-03-25 | 1999-09-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-09-23 | 2003-03-25 | 2003-09-24 | $7700.00 | Window Closed / Lapsed |