Abstract A magnetic resonance signal of a volume of interest within an object is acquired by placing the object in a magnetic field and the application of three successive steps. The first step comprises an rf selective 90° pulse of frequency f x applied in the presence of an x-gradient magnetic field to select a slice. The magnetization of the slice is then inverted. In the second step an rf selective 90° pulse of frequency f y is applied in the presence of a y-gradient magnetic field to excite a strip of the slice, in the third step an rf selective 180° pulse of frequency f z is applied in the presence of a y-gradient magnetic field to refocus the magnetization of a region of said strip. The resulting free induction signal is derived solely from said region.
A method of obtaining a nuclear magnetic resonance signal from a region of an object comprising subjecting the object to a static magnetic field and carrying out the following steps: 1) applying an rf selective 90° pulse in the presence of a first gradient magnetic field and applying at least one non-selective rf pulse in the absence of a gradient magnetic field so as to dephase incoherently all magnetisation in the object except in a slice orthogonal to the gradient direction of the said first gradient magnetic field; 2) in the presence of a second gradient magnetic field having a gradient extending in a direction generally orthogonal to said one direction and the said static magnetic field, applying an rf selective 90° pulse to tip into a plane perpendicular to the direction of the said static magnetic field a strip defined by the intersection of the aforesaid slice and slice orthogonal to the gradient direction of said second gradient magnetic field; and 3) in the presence of a third gradient magnetic field having a gradient direction extending generally orthogonally to the gradient directions of both the first and second gradient magnetic fields, applying an rf signal to refocus the spins of nuclei in a region defined by the intersection of said strip and a slice orthogonal to the gradient direction of said third gradient magnetic field so that the resulting free induction echo signal arises from the said region alone.
Claim 2
Independent Claim
240 words
A method of obtaining a nuclear magnetic resonance signal from a region of an object comprising subjecting the object to a static magnetic field and carrying out the following steps: 1) applying an rf selective 90° pulse in the presence of a first gradient magnetic field and applying at least one non-selective rf pulse in the absence of a gradient magnetic field so as to dephase incoherently all magnetisation in the object except in a slice orthogonal to the gradient direction of the said first gradient magnetic field; 2) in the presence of a second gradient magnetic field having a gradient extending in a direction generally orthogonal to said one direction and the said static magnetic field, applying an rf selective 90° pulse to tip into a plane perpendicular to the direction of the said static magnetic field a strip defined by the intersection of the aforesaid slice and slice orthogonal to the gradient direction of said second gradient magnetic field; and 3) in the presence of a third gradient magnetic field having a gradient direction extending generally orthogonally to the gradient directions of both the first and second gradient magnetic fields, applying an rf signal to refocus the spins of nuclei in a region defined by the intersection of said strip and a slice orthogonal to the gradient direction of said third gradient magnetic field so that the resulting free induction echo signal arises from the said region alone.
Claim 3
Dependent Claim
126 words
The method as claimed in claim 1 in which step 1) comprises the following sub-steps: a) applying an rf selective 90° pulse in the presence of the first gradient magnetic field so as to flip the magnetisation in the said slice into a plane perpendicular to the direction of the said static magnetic field; b) applying a non-selective rf 180° pulse in the absence of a gradient magnetic field and separately applying a gradient magnetic field to refocus the magnetisation in the said slice; c) applying an rf non-selective 90° pulse in the absence of a gradient magnetic field so as to flip the refocused magnetisation of the nuclei in the said slice along a direction parallel to the direction of the said static magnetic field.
Claim 4
Dependent Claim
28 words
The method as claimed in claim 1 in which step 1) includes also applying at least one gradient magnetic field pulse in the absence of an rf pulse.
Claim 5
Dependent Claim
42 words
The method as claimed in claim 2 in which after the sub-steps a) to c) a sub-step d) is applied comprising a magnetic field gradient pulse having a gradient in said one direction sufficient to destroy the magnetisation outside the said slice.
Claim 6
Dependent Claim
56 words
The method as claimed in claim 1 in which step 3) comprises the application of an rf selective 180° pulse in the presence of said third magnetic gradient field followed by a magnetic gradient field pulse having a gradient in the said second direction of duration sufficient to refocus the magnetisation in the region of interest.
Claim 7
Independent Claim
60 words
The method as claimed in any one of the preceding claims in which a phase-encoding magnetic field gradient orthogonal to said one direction is interposed between steps 2) and step 3) and a free-induction signal is acquired in the presence of a magnetic field gradient in said one direction so that the signal contains image information of the said region.