US5047258A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Aqueous spray-coating process
Assignee: STWB Inc
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Filing: 1990-12-04
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Granted: 1991-09-10
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Expires: 2010-12-04
Abstract
Abstract A process for spray-coating tablets and the like utilizing only an acrylate enteric polymer and plasticizer in water is disclosed. The process can be practiced on a commercial scale and requires no antiadherent in the coating formulation. The process comprises providing inlet air having a dew point below about 10° C. and a temperature between 35° and 60° C.
Inventors
- 👤 Raymond J. Belanger
- 👤 Gregg Stetsko
- 👤 Shrikant N. Pagay
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:42
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2893; A61K9/2806; A61K9/2833; A61K9/284; A61K9/2846
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
66 words
A method of preventing pharmaceutical dosage forms from adhering during spray coating, comprising: spraying said pharmaceutical dosage forms in the absence of glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
Claim 2
Independent Claim
66 words
A method of preventing pharmaceutical dosage forms from adhering during spray coating, comprising: spraying said pharmaceutical dosage forms in the absence of glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
Claim 3
Dependent Claim
20 words
A method according to claim 1 wherein said dosage forms individually weight from about 60 mg to about 1500 mg.
Claim 4
Dependent Claim
36 words
A method according to claim 2 wherein the dew point of said inlet air is below about 5° C. and the temperature of said inlet air is between about 40° C. and about 50 ° C.
Claim 5
Dependent Claim
25 words
A method according to claim 2 wherein the total weight of said pharmaceutical dosage forms being spray-coated in one batch is greater than 140 kg.
Claim 6
Independent Claim
63 words
A method of preventing tablets from adhering during spray coating, comprising: spraying said tablets in the absence of a glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
Claim 7
Independent Claim
63 words
A method of preventing tablets from adhering during spray coating, comprising: spraying said tablets in the absence of a glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
Claim 8
Dependent Claim
18 words
A method according claim 5 wherein said tablets individually weigh from about 60 mg to about 1500 mg.
Claim 9
Dependent Claim
23 words
A method according to claim 6 wherein the total weight of said tablets being spray-coated in one batch is greater than 140 kg.
Claim 10
Dependent Claim
15 words
A method according to claim 7 wherein said tablets contain aspirin as the active ingredient.
Claim 11
Dependent Claim
18 words
A method according to claim 8 wherein said tablets individually weigh from about 60 to about 650 mg.
Claim 12
Dependent Claim
15 words
A method according to claim 5 wherein said tablets contain aspirin as the active ingredient.
Claim 13
Dependent Claim
18 words
A method according to claim 10 wherein said tablets individually weigh from about 60 to about 650 mg.
Claim 14
Dependent Claim
32 words
A method according to claim 5 wherein the dew point of said inlet air is below about 5° C. and said inlet air is from about 40° C. to about 50° C.
Claim 15
Dependent Claim
24 words
A method according to claim 12 wherein the total weight of said tablets being aqueous spray-coated in one batch is greater than 140 kg.
Claim 16
Dependent Claim
15 words
A method according to claim 13 wherein said tablets contain aspirin as the active ingredient.
Claim 17
Dependent Claim
15 words
A method according to claim 14 wherein said plasticizer in said spray-coating mixture is triacetin.
Claim 18
Dependent Claim
19 words
A method according to claim 15 wherein said tablets weigh individually from about 60 mg to about 650 mg.
Claim 19
Dependent Claim
16 words
A method according to claim 16 wherein said tablets contain individually about 325 mg of aspirin.
Claim 20
Independent Claim
75 words
A method of preventing batches of aspirin tablets containing more than 140 kg of tablets from adhering during spray coating, comprising: spraying said batches of tablets in the absence of a glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
Claim 21
Independent Claim
75 words
A method of preventing batches of aspirin tablets containing more than 140 kg of tablets from adhering during spray coating, comprising: spraying said batches of tablets in the absence of a glidant with a mixture consisting essentially of a one to one copolymer of ethyl acrylate and methacrylic acid and a plasticizer in air having an inlet dew point below about 10° C. and an inlet temperature between about 35° C. and about 60° C.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-09-09 | 1995-03-11 | 1995-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-09-09 | 1999-03-11 | 1999-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-09-09 | 2003-03-11 | 2003-09-10 | $7700.00 | Window Closed / Lapsed |