US5043335A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Indolocarbazoles and the use thereof
Assignee: Goedecke GmbH
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Filing: 1990-07-23
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Granted: 1991-08-27
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Expires: 2010-07-23
Abstract
Abstract The present invention provides 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo [1,2,3-fg: 3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione and 9,10,11,12-tetrahydro-2-(tetrahydro-5-methoxy-2-furanyl) -9,12-epoxy-1H-diindolo[1,2,3-fg: 3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione process for the preparation thereof, pharmaceutical compositions containing the compounds, and use of the compounds in heart and blood vessel diseases such as thromboses, arterioscleroses, hypertension and inflammatory diseases, allergies, cancer and certain degenerative damage of the central nervous system, as well as diseases of the immune system.
Inventors
- 👤 Jurgen Kleinschroth
- 👤 Johannes Hartenstein
- 👤 Christoph Schachtele
- 👤 Claus Rudolph
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:07
CPC Classifications
C; C07; C07D; C07D498/00; C07D498/22; A; A61; A61P; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P37/00; A61P37/02; A61P37/08; A61P43/00; A61P7/00; A61P7/02; A61P9/00; A61P9/10; A61P9/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
4 words
A compound named 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione.
Claim 2
Dependent Claim
4 words
A compound named 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione.
Claim 3
Dependent Claim
5 words
A compound named 9,10,11,12-tetrahydro-2-(tetrahydro-5-methoxy-2-furanyl)-9,12-epoxy-1H-diindolo [1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione.
Claim 4
Dependent Claim
5 words
A compound named 9,10,11,12-tetrahydro-2-(tetrahydro-5-methoxy-2-furanyl)-9,12-epoxy-1H-diindolo [1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione.
Claim 5
Dependent Claim
26 words
A pharmaceutical composition comprising a therapeutically effective amount of a compound as defined in claim 1 or claim 2 in combination with a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim
30 words
A method for treating heart and blood vessel diseases which comprises administering to a mammal in need of such treatment a composition according to claim 3 in unit dosage form.
References Cited (Backward Citations)
US4923986A
Cited
EP0296110A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-08-26 | 1995-02-25 | 1995-08-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-08-26 | 1999-02-25 | 1999-08-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-08-26 | 2003-02-25 | 2003-08-27 | $7700.00 | Window Closed / Lapsed |