US5016647A
Expired / Lapsed
US
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Method for controlling the glottic opening
Assignee: Icahn School of Medicine at Mount Sinai
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Filing: 1989-11-03
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Granted: 1991-05-21
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Expires: 2009-11-03
Abstract
Abstract A method and devices for transcutaneous or transmucosal stimulation of the recurrent laryngeal nerve are provided. Recurrent laryngeal nerve stimulation is delivered by applying electric charge from an electrode in the form of a probe or an indwelling device to the intact neck skin at specific points along the tracheoesophageal groove or to mucosa within the esophagus, larynx, or trachea. In accordance with the present invention vocal cord excursion is related to frequency of the electrical stimulus.
Inventors
- 👤 Ira Sanders
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 17:22
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/3601
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
84 words
A method for controllably indirectly stimulating the glottic opening of an animal comprising generating a periodic electrical stimulus and applying the periodic electrical stimulus to a predetermined anatomical site such that the stimulus is transmitted from said predetermined anatomical site to the recurrent laryngeal nerve, said stimulus having a frequency which is selected to evoke a predetermined amount of stimulation in at least one intrinsic larynegeal muscle, and having a current effective to selectively stimulate at least a portion of the recurrent larynegeal nerve.
Claim 2
Independent Claim
84 words
A method for controllably indirectly stimulating the glottic opening of an animal comprising generating a periodic electrical stimulus and applying the periodic electrical stimulus to a predetermined anatomical site such that the stimulus is transmitted from said predetermined anatomical site to the recurrent laryngeal nerve, said stimulus having a frequency which is selected to evoke a predetermined amount of stimulation in at least one intrinsic larynegeal muscle, and having a current effective to selectively stimulate at least a portion of the recurrent larynegeal nerve.
Claim 3
Dependent Claim
38 words
The method according to claim 1 wherein the periodic electrical stimulus is a cathodic pulse having a pulse duration in the order of 0.01 to 10 milliseconds and a pulse frequency between 1 and 100 pulses per second.
Claim 4
Dependent Claim
37 words
The method according to claim 1 wherein the electrical stimulus is a current which elicits contraction of at least one extrinsic laryngeal muscle without significantly influencing other, one-larynegeal, nerves passing through the neck region of the animal.
Claim 5
Dependent Claim
31 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord abduction, and is applied to intack neck skin along the tracheo-esophageal groove.
Claim 6
Dependent Claim
21 words
The method according to claim 4 wherein the stimulus is a current having a frequency of less than about 40 Hz.
Claim 7
Dependent Claim
32 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord adduction, and is applied to a intack neck skin along the tracheoesophageal groove.
Claim 8
Dependent Claim
21 words
The method according to claim 6 wherein the stimulus is a current having a frequency of greater than about 40 Hz.
Claim 9
Dependent Claim
48 words
The method according to claim 1 wherein the periodic electrical stimulus is applied to the anatomical site by an electrode having an area of contact defined by a circle having a diameter of less than about 5 mm. by placing the electrode in contact with the anatomical site.
Claim 10
Dependent Claim
37 words
The method according to claim 1 wherein the anatomical site is laryngeal muscle tissue, and said stimulus has a triangular wave form effective to stimulate denervated muscle and ineffective to stimulate muscle having a live nerve supply.
Claim 11
Dependent Claim
27 words
The method according to claim 1 wherein the anatomical site is laryngeal muscle tissue, and said stimulus has a square wave form effective to stimulate denervated muscles.
Claim 12
Dependent Claim
17 words
The method according to claim 10 wherein the current of the square wave stimulus is 20 millilamps.
Claim 13
Dependent Claim
18 words
The method according to claim 1 wherein the anatomical site is intact neck skin along the tracheoescophageal groove.
Claim 14
Dependent Claim
28 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord adduction, and is applied to the tracheal wall posteriolaterally.
Claim 15
Dependent Claim
28 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord adduction, and is applied to the esophageal wall anteriolaterally.
Claim 16
Dependent Claim
28 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord abduction and is applied to the tracheal wall posteriolaterally.
Claim 17
Dependent Claim
28 words
The method according to claim 1 wherein the periodic electrical stimulus is a current effective to cause vocal cord abduction and is applied to the esophageal wall anteriolaterally.
Claim 18
Dependent Claim
14 words
The method according to claim 1 wherein the anatomical site is laryngeal muscle tissue.
Claim 19
Dependent Claim
18 words
The method according to claim 1 wherein the anatomical site is intact neck skin along the tracheoesophageal groove.
Claim 20
Dependent Claim
16 words
The method according to claim 1 wherein the anatomical site is through the tracheal wall posterolaterally.
Claim 21
Dependent Claim
16 words
The method according to claim 1 wherein the anatomical site is through the esophageal wall anteriolaterally.
Claim 22
Independent Claim
66 words
A device for controllably stimulating the glottic opening of an animal comprising a means for generating and a means for applying a periodic electrical stimulus at a predetermined anatomical site, the stimulus having a frequency which evokes a predetermined amount of stimulation in a least one intrinsic laryngeal muscle and having a current effective to selectively stimulate at least a portion of the recurrent laryngeal nerve.
Claim 23
Independent Claim
66 words
A device for controllably stimulating the glottic opening of an animal comprising a means for generating and a means for applying a periodic electrical stimulus at a predetermined anatomical site, the stimulus having a frequency which evokes a predetermined amount of stimulation in a least one intrinsic laryngeal muscle and having a current effective to selectively stimulate at least a portion of the recurrent laryngeal nerve.
Claim 24
Dependent Claim
19 words
A device as in claim 21 in which the means for applying a periodic electrical stimulus is an electrode.
References Cited (Backward Citations)
US2842136A
Cited
US4351330A
Cited
US4334542A
Cited
US4503863A
Cited
US4553549A
Cited
US4715367A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-05-20 | 1994-11-19 | 1995-05-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-05-20 | 1998-11-19 | 1999-05-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-05-20 | 2002-11-19 | 2003-05-21 | $7700.00 | Window Closed / Lapsed |