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US5008244A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for increasing fertility in animals

Assignee: Mallinckrodt Veterinary Inc
•
Filing: 1989-05-15
•
Granted: 1991-04-16
•
Expires: 2009-05-15
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Abstract

Abstract Somatotropin is administered to food producing animals in the finishing stage of growth to increase fertility by increasing embryonic survival and litter size during the reproductive stage of growth.

Inventors

  • 👤 Lindy F. Miller
  • 👤 Peter J. Thomford

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 23:15
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/27

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 48 words
A method for increasing fertility in a food producing animal selected from the bovine, porcine or ovine species, comprising: administering a fertility increasing amount of somatotropin to said animal in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.
Claim 2
Independent Claim 48 words
A method for increasing fertility in a food producing animal selected from the bovine, porcine or ovine species, comprising: administering a fertility increasing amount of somatotropin to said animal in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.
Claim 3
Dependent Claim 17 words
The method of claim 1 wherein said somatotropin is administered in amounts of from about 0.1-20 mg/animal/day.
Claim 4
Dependent Claim 13 words
The method of claim 1 wherein said animal is from the porcine species.
Claim 5
Dependent Claim 11 words
The method of claim 1 wherein said somatotropin is administered parenterally.
Claim 6
Dependent Claim 31 words
The method of claim 4 wherein said somatotropin is administered using an implant, said implant comprising: a biocompatible and somatotropin compatible implant material; and a fertility increasing amount of said somatotropin.
Claim 7
Dependent Claim 32 words
The method of claim 4 wherein said somatotropin is administered in an injectable formulation, said injectable formulation comprising: a biocompatible and somatotropin compatible carrier; and a fertility increasing amount of said somatotropin.
Claim 8
Dependent Claim 22 words
The method of claim 5 wherein said carrier is a buffer containing about 300 mg/ml arginine hydrochloride and about 0.9% benzyl alcohol.
Claim 9
Dependent Claim 12 words
The method of claim 1 wherein said somatotropin is a recombinant somatotropin.
Claim 10
Dependent Claim 18 words
The method of claim 8 wherein said somatotropin is delta-7 recombinant porcine somatotropin or delta-9 recombinant bovine somatotropin.
Claim 11
Dependent Claim 13 words
The method of claim 3 wherein said somatotropin is delta-7 recombinant porcine somatotropin.
Claim 12
Independent Claim 39 words
A method for increasing fertility in a swine, comprising: administering a fertility increasing amount of porcine somatotropin to said swine in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.
Claim 13
Independent Claim 39 words
A method for increasing fertility in a swine, comprising: administering a fertility increasing amount of porcine somatotropin to said swine in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.
Claim 14
Dependent Claim 17 words
The method of claim 11 wherein said somatotropin is administered in amounts of from about 0.1-20 mg/swine/day.
Claim 15
Dependent Claim 11 words
The method of claim 11 wherein said somatotropin is administered parenterally.
Claim 16
Dependent Claim 31 words
The method of claim 13 wherein said somatotropin is administered using an implant, said implant comprising: a biocompatible and somatotropin compatible implant material; and a fertility increasing amount of said somatotropin.
Claim 17
Dependent Claim 32 words
The method of claim 13 wherein said somatotropin is administered in an injectable formulation, said injectable formulation comprising: a biocompatible and somatotropin compatible carrier; and a fertility increasing amount of said somatotropin.
Claim 18
Dependent Claim 22 words
The method of claim 15 wherein said carrier is a buffer containing about 300 mg/ml arginine hydrochloride and about 0.9% benzyl alcohol.
Claim 19
Dependent Claim 12 words
The method of claim 11 wherein said somatotropin is a recombinant somatotropin.
Claim 20
Dependent Claim 13 words
The method of claim 17 wherein said somatotropin is delta-7 recombinant porcine somatotropin.
Claim 21
Dependent Claim 17 words
The method of claim 11 wherein said somatotropin is administered in amounts of from about 3-12 mg/swine/day.
Claim 22
Independent Claim 41 words
A method for increasing fertility in a swine, comprising: administering from about 0.1-20 mg/swine/day of delta-7 recombinant porcine somatotropin to said swine in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.
Claim 23
Independent Claim 41 words
A method for increasing fertility in a swine, comprising: administering from about 0.1-20 mg/swine/day of delta-7 recombinant porcine somatotropin to said swine in the finishing stage of growth thereby increasing embryonic survival and litter size during the reproductive stage of growth.

References Cited (Backward Citations)

US4061737A Cited
US4521409A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-04-15 1994-10-15 1995-04-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-04-15 1998-10-15 1999-04-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-04-15 2002-10-15 2003-04-16 $7700.00 Window Closed / Lapsed

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