US5004826A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted propane-phosphonous acid compounds
Assignee: Novartis Corp
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Filing: 1989-12-01
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Granted: 1991-04-02
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Expires: 2009-12-01
Abstract
Abstract The compounds of the formula ##STR1## in which one of the groups R 1 , R 2 and R 3 represents hydrogen, C 1-8 -alkyl, C 3-6 -cycloalkyl, phenyl optionally substituted by halogeno, C.sub. 1-4 -alkyl, C.sub. -4 -alkoxy and/or trifluoromethyl, or C 7-10 -phenylalkyl optionally substituted in the phenyl moiety by halogeno, C 1-4 -alkyl C 1-4 -alkoxy and/or trifluormethyl, and the other two are hydrogen, or salts thereof. These compounds have valuable pharmaceutical properties.
Inventors
- 👤 John G. Dingwall
- 👤 Josef Ehrenfreund
- 👤 Roger G. Hall
- 👤 James Jack
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 17:43
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/48; A; A61; A61P; A61P21/00; A61P25/00; A61P25/04; A61P25/24; A61P25/26; A61P25/28; C07F9/30; C07F9/32; C07F9/3205; C07F9/3211; C07F9/4808; C07F9/4816; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
130 words
A compound having the formula II ##STR27## in which one of the groups R 1 , R 2 and R 3 represents hydrogen, C 1 -C 8 alkyl, C 3 -C 6 -cycloalkyl, phenyl either unsubstituted or substituted by halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy and/or trifluoromethyl, or phenyl-C 1 -C 4 alkyl either unsubstituted or substituted in the phenyl moiety by halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy and/or trifluoromethyl, and the other two are hydrogen, Q denotes a group having the formula --C(C.sub.1 -C.sub.4 alkyl)(OR.sup.a)OR.sup.b, in which R a and R b are each C 1 -C 4 alkyl, R c is C 1 -C 4 alkyl and Z denotes --NH 2 , or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
130 words
A compound having the formula II ##STR27## in which one of the groups R 1 , R 2 and R 3 represents hydrogen, C 1 -C 8 alkyl, C 3 -C 6 -cycloalkyl, phenyl either unsubstituted or substituted by halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy and/or trifluoromethyl, or phenyl-C 1 -C 4 alkyl either unsubstituted or substituted in the phenyl moiety by halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy and/or trifluoromethyl, and the other two are hydrogen, Q denotes a group having the formula --C(C.sub.1 -C.sub.4 alkyl)(OR.sup.a)OR.sup.b, in which R a and R b are each C 1 -C 4 alkyl, R c is C 1 -C 4 alkyl and Z denotes --NH 2 , or a pharmaceutically acceptable salt thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-01 | 1994-10-01 | 1995-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-01 | 1998-10-01 | 1999-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-01 | 2002-10-01 | 2003-04-02 | $7700.00 | Window Closed / Lapsed |