US5004737A
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Quaternary ammonium-substituted sterol derivatives
Assignee: Pacific Corp
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Filing: 1989-09-22
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Granted: 1991-04-02
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Expires: 2009-09-22
Abstract
Abstract The present invention relates to a novel quaternary ammonium-substituted sterol derivative of the following formula: ##STR1## wherein Q represents an anion of a strong inorganic acid, A represents an oxygen, R 1 , R 2 , R 3 , t, n, and the sterol Rst are defined as herein. The compounds of the present invention as a result of introducing a cationic group into hydroxy group of sterols of ethoxylated compounds thereof which are non-ionic, shows the enhanced substantivity against substrate having, on its surface, an anionic characters under normal conditions such as skin and hair of human being. The compound of the present invention can be used in the field of cosmetics.
Inventors
- 👤 Young D. Kim
- 👤 Byung J. Ha
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 23:33
CPC Classifications
C; C07; C07J; C07J41/00; C07J41/0005; C07J41/0033; C07J41/0055
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
110 words
A quaternary ammonium-substituted sterol compound of the following formula (I): ##STR17## wherein Q represents an anion of a strong inorganic acid, R 1 represents alkyl or a monounsaturated alkenyl group having up to 18 carbon atoms; R 2 and R 3 , the same or different from each other, are methyl or ethyl groups; t is the valence of Q; A represents an oxygen atom; n is an integer of 0 to 25; and Rst represents a sterol selected from the group consisting of sitosterol, campesterol, stigmasterol, cholesterol, and lanosterol or a stanol obtained by the reduction of the double bond between carbon atoms 5 and 6 of said sterols.
Claim 2
Dependent Claim
110 words
A quaternary ammonium-substituted sterol compound of the following formula (I): ##STR17## wherein Q represents an anion of a strong inorganic acid, R 1 represents alkyl or a monounsaturated alkenyl group having up to 18 carbon atoms; R 2 and R 3 , the same or different from each other, are methyl or ethyl groups; t is the valence of Q; A represents an oxygen atom; n is an integer of 0 to 25; and Rst represents a sterol selected from the group consisting of sitosterol, campesterol, stigmasterol, cholesterol, and lanosterol or a stanol obtained by the reduction of the double bond between carbon atoms 5 and 6 of said sterols.
Claim 3
Dependent Claim
11 words
A sterol compound of claim 1, wherein the stanol represents cholestanol.
Claim 4
Dependent Claim
20 words
The compound of claim 1, wherein Q is a halogen selected from the group consisting of chlorine, bromine, and iodine.
Claim 5
Dependent Claim
9 words
The compound of claim 1, wherein Q is chlorine.
Claim 6
Dependent Claim
9 words
The compound of claim 1, wherein Q is bromine.
Claim 7
Dependent Claim
9 words
The compound of claim 1, wherein Q is iodine.
References Cited (Backward Citations)
US2889318A
Cited
US3013009A
Cited
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