US5002889A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Reaction well shape for a microwell tray
Assignee: Genetic Systems Corp
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Filing: 1988-10-21
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Granted: 1991-03-26
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Expires: 2008-10-21
Abstract
Abstract A microwell for enzyme-linked immunosorbent assays has a concavely curved, circumferential sidewall, a flat optical bottom and a top lip, including smooth transitions between the top lip, concave sidewall and flat bottom. This shape minimizes the tendency of fluid to cling to the well for washing efficiency and maximizes a vertical optical path length of fluid in the well for improved optical determination.
Inventors
- 👤 Gerald L. Klein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 16:58
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/508; B01L3/5085
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
160 words
An apparatus comprising a molded device having a plurality of reaction wells adapted for photometric determination of a fluid characteristic, each reaction well having a volume capacity of less than one milliliter and comprising; a convexly curved, circumferential top lip centered about a vertical well axis and defining an opening for the well; a concavely curved, circumferential sidewall centered about the well axis and contiguous with the top lip and having a radiums of curvature of approximately 0.38 inch as measured about the vertical well axis approximately 0.223 inches above a well bottom; a concavely curved, circumferential transition wall centered about the well axis and contiguous with the circumferential sidewall; and a circular, planar optical window centered about the well axis and contiguous with the transition wall so as to define the bottom for the well, wherein the circumferential top lip and circumferential transition wall have radii of curvature substantially less than the radius of curvature of the circumferential sidewall.
Claim 2
Independent Claim
160 words
An apparatus comprising a molded device having a plurality of reaction wells adapted for photometric determination of a fluid characteristic, each reaction well having a volume capacity of less than one milliliter and comprising; a convexly curved, circumferential top lip centered about a vertical well axis and defining an opening for the well; a concavely curved, circumferential sidewall centered about the well axis and contiguous with the top lip and having a radiums of curvature of approximately 0.38 inch as measured about the vertical well axis approximately 0.223 inches above a well bottom; a concavely curved, circumferential transition wall centered about the well axis and contiguous with the circumferential sidewall; and a circular, planar optical window centered about the well axis and contiguous with the transition wall so as to define the bottom for the well, wherein the circumferential top lip and circumferential transition wall have radii of curvature substantially less than the radius of curvature of the circumferential sidewall.
Claim 3
Dependent Claim
14 words
The reaction well of claim 1 wherein the circumferential sidewall has a parabolic shape.
Claim 4
Dependent Claim
15 words
The reaction well of claim 1 wherein the circumferential sidewall is a surface of revolution.
Claim 5
Dependent Claim
24 words
The reaction well of claim 1 wherein the circumferential top lip and circumferential transition wall have a radius of curvature of approximately 0.012 inch.
Claim 6
Dependent Claim
18 words
The reaction well of claim 4 wherein the circumferential top lip has a diameter of approximately 0.22 inch.
Claim 7
Dependent Claim
17 words
The reaction well of claim 5 wherein the optical window has a diameter of approximately 0.059 inch.
Claim 8
Dependent Claim
34 words
The reaction well of claim 6 wherein the well has a height, defined by a distance between the circumferential top lip and the optical window, of approximately 0.180 inch measured along the well axis.
Claim 9
Dependent Claim
24 words
The reaction well of claim 1 wherein the circumferential top lip and circumferential sidewall have tangents, at respective contiguous portions thereof, which are parallel.
Claim 10
Dependent Claim
24 words
The reaction well of claim 1 wherein the circumferential sidewall and circumferential transition wall have tangents, at respective contiguous portions thereof, which are parallel.
Claim 11
Dependent Claim
28 words
The well shape of claim 1 wherein the circumferential sidewalls, and the circumferential top lip and transition wall, have tangents, at respective contiguous portions thereof, which are parallel.
Claim 12
Independent Claim
114 words
An apparatus comprising a molded device having a plurality of reaction wells for photometric determination of a fluid characteristic, each well having a volume capacity of less than one milliliter and the shape of the well comprising; a circumferential top lip defining an open top for the well; a peripheral, substantially concavely curved sidewall contiguous with the top lip and having a smooth transition therebetween and having a radius of curvature of approximately 0.38 inch as measured above a well bottom; and axis approximately 0.223 inches above a well bottom; and a substantially flat optical window connected to the curved sidewall and having a smooth transition there between defining the bottom for the well.
Claim 13
Independent Claim
114 words
An apparatus comprising a molded device having a plurality of reaction wells for photometric determination of a fluid characteristic, each well having a volume capacity of less than one milliliter and the shape of the well comprising; a circumferential top lip defining an open top for the well; a peripheral, substantially concavely curved sidewall contiguous with the top lip and having a smooth transition therebetween and having a radius of curvature of approximately 0.38 inch as measured above a well bottom; and axis approximately 0.223 inches above a well bottom; and a substantially flat optical window connected to the curved sidewall and having a smooth transition there between defining the bottom for the well.
Claim 14
Dependent Claim
14 words
The well shape of claim 11 wherein the curved sidewall has a parabolic curve.
Claim 15
Dependent Claim
15 words
The well shape of claim 11 wherein the curved a sidewall has a spherical curve.
Claim 16
Dependent Claim
18 words
The apparatus of claim 1, wherein the reaction wells are combined in a row to form a strip.
Claim 17
Dependent Claim
18 words
The apparatus of claim 11, wherein the reaction wells are combined in a row to form a strip.
Claim 18
Dependent Claim
13 words
The apparatus of claim 11, wherein the wells are formed in a place.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-03-25 | 1994-09-24 | 1995-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-03-25 | 1998-09-24 | 1999-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-03-25 | 2002-09-24 | 2003-03-26 | $7700.00 | Window Closed / Lapsed |