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US4981483A Expired / Lapsed US ⏱️ 0.0 years remaining

Biocompatible material for treatment of tissular or organic defects

Assignee: Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena
•
Filing: 1987-01-14
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Granted: 1991-01-01
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Expires: 2007-01-14
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Abstract

Abstract A biocompatible material for treatment of tissular or organic defects is composed of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________ alpha-cyanacrylate 14 to 34 polyacrylic acid having a molecular weight of 200,000 to 600,000 15 to 43 cross-linking agent 71 to 23 ______________________________________ .

Inventors

  • 👤 Alla Y. Akimova
  • 👤 Anatoly B. Davydov
  • 👤 Valery N. Egiev
  • 👤 Anna I. Iliina
  • 👤 Jury P. Kapustin
  • 👤 Anesty K. Orfanidi
  • 👤 Alexei N. Smirnov
  • 👤 Eduard A. Stepanov
  • 👤 Valeria I. Timokhina
  • 👤 Anatoly Nikolaevich Chigir
  • 👤 Kirill G. Schitkov

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 03:57
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/04; A61L24/06; A61L26/00; A61L26/0009; A61L26/0014; A61P; A61P17/00; A61P43/00; Y; Y10; Y10S; Y10S623/00; Y10S623/92

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 92 words
A biocompatible material for treatment of tissular or organic defects in a patient, said material comprised of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanoacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________ alpha-cyanoacrylate 14 to 34 polyacrylic acid having a molecular weight of 200,000 to 600,000 15 to 43 cross-linking agent 71 to 23 ______________________________________ and wherein said material is resorbable by said patient.
Claim 2
Dependent Claim 92 words
A biocompatible material for treatment of tissular or organic defects in a patient, said material comprised of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular weight of 200,000 to 600,000, obtained by interaction of alpha-cyanoacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows: ______________________________________ alpha-cyanoacrylate 14 to 34 polyacrylic acid having a molecular weight of 200,000 to 600,000 15 to 43 cross-linking agent 71 to 23 ______________________________________ and wherein said material is resorbable by said patient.
Claim 3
Dependent Claim 19 words
A biocompatible material as claimed in claim 1, which comprises, as said alpha-cyanoacrylate, ethyl-alpha-cyanoacrylate, ethoxyethyl-alpha-cyanoacrylate, butyl-alpha-cyanoacrylate, or mixtures thereof.
Claim 4
Dependent Claim 31 words
A biocompatible material as claimed in claims 1 or 2, wherein said cross-linking agent is polyvinyl alcohol having a molecular weight of 500,000 to 600,000, glycerol or a mixture of both.
Claim 5
Dependent Claim 24 words
A biocompatible material as claimed in claims 1 or 2, which comprises additionally an antiseptic in an amount of 9 to 50 weight percent.

References Cited (Backward Citations)

US3667472A Cited
US3759264A Cited
GB1221282A Cited
US3630194A Cited
US4316457A Cited
BE899078A Cited
US4746544A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-12-31 1994-07-02 1995-01-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-12-31 1998-07-02 1999-01-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-12-31 2002-07-02 2003-01-01 $7700.00 Window Closed / Lapsed

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