US4978676A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of skin diseases with artemisinin and derivatives
Assignee: Dermatologic Research Corp
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Filing: 1989-04-10
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Granted: 1990-12-18
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Expires: 2009-04-10
Abstract
Abstract Psoriasis, ultraviolet light induced skin conditions and tumors are successfully treated with topical or oral administration of artemisinin, dihydroartemisinin, its semisynthetic derivatives and its synthetic analogs. Viral tumors/diseases, hemorrhoids, and bullous skin diseases are also successfully treated with these topical compositions.
Inventors
- 👤 Carl R. Thornfeldt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 06:27
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/365; A61K31/38; A61K31/39; C; C08; C08G; C08G67/00; C08G67/04; C08G69/00; C08G69/02; C08G69/08; C08G69/10
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
61 words
A method for the treatment of a subject suffering from psoriasis, said method comprising administering to said subject a therapeutically effective amount of a compound having the formula ##STR5## in which R is a member selected from the group consisting of ##STR6## where R' is a member selected from the group consisting of ##STR7## in which M is sodium or potassium.
Claim 2
Independent Claim
61 words
A method for the treatment of a subject suffering from psoriasis, said method comprising administering to said subject a therapeutically effective amount of a compound having the formula ##STR5## in which R is a member selected from the group consisting of ##STR6## where R' is a member selected from the group consisting of ##STR7## in which M is sodium or potassium.
Claim 3
Dependent Claim
17 words
A method in accordance with claim 1 in which said compound is a synthetic analog of dihydroartemisinin.
Claim 4
Dependent Claim
14 words
A method in accordance with claim 1 in which said compound is artelinic acid.
Claim 5
Dependent Claim
28 words
A method in accordance with claim 1 in which said compound is a semisynthetic derivative of dihydroartemisinin selected from the group consisting of esters, ethers, carbonates and sulfonates.
Claim 6
Dependent Claim
28 words
A method in accordance with claim 1 in which said compound is a member selected from the group consisting of artemisinin, dihydroartemisinin, artemether, artesunate, and dihydroartemisinin propyl carbonate.
Claim 7
Dependent Claim
50 words
A method in accordance with claim 1 in which said compound is a member selected from the group consisting of artemisinin, dihydroartemisinin, artemether, artesunate, and dihydroartemisinin propyl carbonate; and said method further comprises administering said compound in combination with a member selected from the group consisting of N-methyl-2-pyrrolidone and dimethylacetamide.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-12-17 | 1994-06-18 | 1994-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-12-17 | 1998-06-18 | 1998-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-12-17 | 2002-06-18 | 2002-12-18 | $7700.00 | Window Closed / Lapsed |