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US4966894A Expired / Lapsed US ⏱️ 0.0 years remaining

Polysulfated heparins for treating diseases caused by retroviruses

Assignee: BASF SE
•
Filing: 1988-12-22
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Granted: 1990-10-30
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Expires: 2008-12-22
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Abstract

Abstract Polysulfated heparins are used for the preparation of drugs for the prophylaxis and therapy of diseases caused by retroviruses.

Inventors

  • 👤 Dieter Herr
  • 👤 Thomas Doerper
  • 👤 Lothar Daum
  • 👤 Karl-Heinz Geiss
  • 👤 Achim Moeller

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 17:06
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61P; A61P31/00; A61P31/12

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 59 words
A method of treating a disease caused by a retrovirus, which comprises administering a polysulfated heparin to a patient suffering from said disease in an amount effective for inhibiting replication of said retrovirus in said patient, said polysulfate heparin having a molecular weight in the range of about 2,000-20,000 and having a sulfur content from about 13.5 to 15%.
Claim 2
Independent Claim 59 words
A method of treating a disease caused by a retrovirus, which comprises administering a polysulfated heparin to a patient suffering from said disease in an amount effective for inhibiting replication of said retrovirus in said patient, said polysulfate heparin having a molecular weight in the range of about 2,000-20,000 and having a sulfur content from about 13.5 to 15%.
Claim 3
Dependent Claim 17 words
The method according to claim 1, wherein said polysulfated heparin has a molecular weight of from 2000-9000.
Claim 4
Dependent Claim 27 words
The method according to claim 1, wherein said polysulfated heparin is in the form of a free acid or in the form of salts with physiologically-acceptable bases.
Claim 5
Dependent Claim 32 words
The method according to claim 1, wherein said polysulfated heparin has a molecular weight in the range of 2,800 to 14,100, and a sulfur content in the range of 13.6 to 14.9%.
Claim 6
Dependent Claim 38 words
The method according to claim 1, wherein said polysulfated heparin is administered in an amount of about 10 to 1,000 mg/kg body weight for oral administration, and of about 0.1 to 10 mg/kg body weight for parenteral administration.

References Cited (Backward Citations)

EP0240098A2 Cited
EP0270317A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-10-29 1994-04-30 1994-10-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-10-29 1998-04-30 1998-10-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-10-29 2002-04-30 2002-10-30 $7700.00 Window Closed / Lapsed

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