US4966699A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hollow fiber membrane fluid processor
Assignee: Terumo Corp
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Filing: 1989-04-10
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Granted: 1990-10-30
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Expires: 2009-04-10
Abstract
Abstract A hollow fiber membrane fluid processing apparatus comprising a housing, a fluid processing hollow fiber membrane bundle in the housing, partitions fluid tightly securing the opposed ends of the fiber bundle to the housing ends, a space being defined by the hollow fiber membrane outer surface, the housing inner surface, and the partitions, inlet and outlet ports for a first fluid disposed in the housing adjacent the opposed ends thereof in fluid communication with the space, and inlet and outlet ports for a second fluid disposed at the housing ends in fluid communication with the interior of the hollow fiber membranes is characterized in that the portion of the hollow fiber membranes in contact with each partition swells little upon contact with water-containing fluid. When contacted with physiological saline for priming and the second fluid for processing, the partition-contacting portion of the hollow fiber membranes does not absorb substantial water or expand in wall thickness, that is, maintains the inner diameter unchanged, avoiding any deleterious effect on second fluid flow and an increase of pressure loss.
Inventors
- 👤 Masatomi Sasaki
- 👤 Hirotomo Morita
- 👤 Yutaka Matsumoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 22:56
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0088; A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1621; B01D61/00; B01D61/24; B01D61/28; B01D63/00; B01D63/02; B01D63/021; B01D63/0233; B01D63/033; B01D65/00; B01D65/02; B01D65/022; B01D67/0093; B01D67/00931; B01D69/00; B01D69/08; B01D2323/00; B01D2323/04; B01D2325/00; B01D2325/36
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
183 words
A hollow fiber membrane blood processing apparatus comprising a housing having opposed open ends, a fiber bundle received in said housing and including a plurality of hollow fiber membranes for processing fluid, partitions fluid tightly securing the opposed ends of the fiber bundle to the corresponding ends of said housing, a space being defined by the outer surface of said hollow fiber membranes, the inner surface of said housing, and the partitions, an inlet and an outlet for a blood processing fluid disposed in said housing adjacent the opposed ends thereof in fluid communication with the space, and an inlet and an outlet for blood disposed at the opposed ends of said housing in fluid communication with the interior of the hollow fiber membranes, characterized in that only the portion of said hollow fiber membranes in the vicinity of where the members are in contact with each of said partitions has been treated with a reagent having a reactive group capable of reaction with a polar group that the hollow fiber membranes possess or a material contained in the hollow fiber membranes possesses.
Claim 2
Dependent Claim
183 words
A hollow fiber membrane blood processing apparatus comprising a housing having opposed open ends, a fiber bundle received in said housing and including a plurality of hollow fiber membranes for processing fluid, partitions fluid tightly securing the opposed ends of the fiber bundle to the corresponding ends of said housing, a space being defined by the outer surface of said hollow fiber membranes, the inner surface of said housing, and the partitions, an inlet and an outlet for a blood processing fluid disposed in said housing adjacent the opposed ends thereof in fluid communication with the space, and an inlet and an outlet for blood disposed at the opposed ends of said housing in fluid communication with the interior of the hollow fiber membranes, characterized in that only the portion of said hollow fiber membranes in the vicinity of where the members are in contact with each of said partitions has been treated with a reagent having a reactive group capable of reaction with a polar group that the hollow fiber membranes possess or a material contained in the hollow fiber membranes possesses.
Claim 3
Dependent Claim
14 words
The apparatus of claim 1 wherein the hollow fiber membranes are adapted for dialysis.
Claim 4
Dependent Claim
32 words
The apparatus of claim 1 wherein the polar group that the hollow fiber membranes posses or a material contained in the hollow fiber membranes possesses is a hydroxyl, amino or carboxyl group.
Claim 5
Dependent Claim
19 words
The apparatus of claim 1 wherein the reactive group is an isocyanate, epoxy, thiocyanate, acid chloride or aldehyde group.
Claim 6
Dependent Claim
30 words
The apparatus of claim 1 wherein the reagent is selected from the group consisting of diphenylmethane diisocyanate, 2,4-tolylene diisocyanate, carbodiimide modified diphenylmethane diisocyanate, hexamethylene diisocyanate, epichlorohydrin, and 1,4-butanediol diglycidyl ether.
Claim 7
Dependent Claim
158 words
A hollow fiber membrane blood processing apparatus a housing having opposed open ends, a fiber bundle received in said housing and including a plurality of hollow fiber membranes for processing fluid, partitions fluid tightly securing the opposed ends of the fiber bundle to the corresponding ends of said housing, a space being defined by the outer surface of said hollow fiber membranes, the inner surface of said housing, and the partitions, an inlet and an outlet for a blood processing fluid disposed in said housing adjacent the opposed ends thereof in fluid communication with the space, and an inlet and an outlet for blood disposed at the opposed ends of said housing in fluid communication with the interior of the hollow fiber membranes, characterized in that only the portion of said hollow fiber membranes in the vicinity of where the membranes are in contact with each of said partitions has a hydrophobic material coated thereon or incorporated therein.
Claim 8
Dependent Claim
158 words
A hollow fiber membrane blood processing apparatus a housing having opposed open ends, a fiber bundle received in said housing and including a plurality of hollow fiber membranes for processing fluid, partitions fluid tightly securing the opposed ends of the fiber bundle to the corresponding ends of said housing, a space being defined by the outer surface of said hollow fiber membranes, the inner surface of said housing, and the partitions, an inlet and an outlet for a blood processing fluid disposed in said housing adjacent the opposed ends thereof in fluid communication with the space, and an inlet and an outlet for blood disposed at the opposed ends of said housing in fluid communication with the interior of the hollow fiber membranes, characterized in that only the portion of said hollow fiber membranes in the vicinity of where the membranes are in contact with each of said partitions has a hydrophobic material coated thereon or incorporated therein.
Claim 9
Dependent Claim
14 words
The apparatus of claim 6 wherein the hollow fiber membranes are adapted for dialysis.
Claim 10
Dependent Claim
18 words
The apparatus of claim 7 wherein the hollow fiber membranes are hydrophilic hollow fiber membranes adapted for dialysis.
Claim 11
Dependent Claim
18 words
The apparatus of claim 6 wherein the partitions are coated on their outside surface with a hydrophobic material.
Claim 12
Dependent Claim
15 words
The apparatus of claim 9 wherein the hydrophobic material is silicone, urethane or fluoride resin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-10-29 | 1994-04-30 | 1994-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-10-29 | 1998-04-30 | 1998-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-10-29 | 2002-04-30 | 2002-10-30 | $7700.00 | Window Closed / Lapsed |