US4965372A
Expired / Lapsed
US
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Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates
Assignee: Pfizer Inc
•
Filing: 1989-06-29
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Granted: 1990-10-23
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Expires: 2009-06-29
Abstract
Abstract Process and intermediates for isopropyl 3S-amino-4-cyclohexyl-2R-hydroxybutyrate and 3S-amino-2R-hydroxy-5-methylhexanoate from R-malic acid. These products are of known utility in the synthesis of certain renin inhibitors.
Inventors
- 👤 Robert W. Dugger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 20:25
CPC Classifications
C; C07; C07C; C07C271/00; C07C271/06; C07C271/08; C07C271/10; C07C271/22; C07C229/00; C07C229/02; C07C229/04; C07C229/06; C07C229/22; C07C229/28; C07C229/34; C07C235/00; C07C235/02; C07C235/04; C07C235/06; C07C235/26; C07C235/32; C07C235/34; C07C59/00; C07C59/235; C07C59/245; C07C59/29; C07C59/40; C07C59/42; C07C59/48; C07D; C07D307/00; C07D307/02; C07D307/34; C07D307/56; C07D307/62; C07C2601/00; C07C2601/12; C07C2601/14; Y; Y10; Y10S; Y10S530/00; Y10S530/86
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
31 words
A cyclic anhydride of the absolute stereochemical formula ##STR16## wherein R is phenyl, isopropyl or cyclohexyl; Z is ##STR17## and R 1 is (C 1 -C 4 ) alkyl or phenyl.
Claim 2
Dependent Claim
31 words
A cyclic anhydride of the absolute stereochemical formula ##STR16## wherein R is phenyl, isopropyl or cyclohexyl; Z is ##STR17## and R 1 is (C 1 -C 4 ) alkyl or phenyl.
Claim 3
Dependent Claim
11 words
A compound of claim 1 wherein R 1 pl is methyl.
Claim 4
Dependent Claim
16 words
The compound of claim 2 wherein X and Y are taken together and R is phenyl.
Claim 5
Dependent Claim
16 words
The compound of claim 2 wherein X and Y are taken together and R is isopropyl.
Claim 6
Dependent Claim
16 words
The compound of claim 2 wherein X and Y are taken together and R is cyclohexyl.
References Cited (Backward Citations)
US4599198A
Cited
US4711958A
Cited
US4711958B1
Cited
US4656269A
Cited
US4656269B1
Cited
US4814342A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-10-22 | 1994-04-23 | 1994-10-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-10-22 | 1998-04-23 | 1998-10-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-10-22 | 2002-04-23 | 2002-10-23 | $7700.00 | Window Closed / Lapsed |