US4962856A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Packaged pharmaceutical product
Assignee: Johnson and Johnson Surgical Vision Inc
•
Filing: 1990-03-23
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Granted: 1990-10-16
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Expires: 2010-03-23
Abstract
Abstract A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before steam sterilizing. The blister packs have Tyvek™ lids and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.
Inventors
- 👤 Douglas V. Carter
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:59
CPC Classifications
B; B65; B65B; B65B55/00; B65B55/02; B65B11/00; B65B11/50; B65B11/52; B65D; B65D75/00; B65D75/28; B65D75/30; B65D75/32; B65D75/325; B65D75/326; B65D75/36
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
165 words
A sterile pharmaceutical package comprising: (a) a translucent, resilient polymeric bottle formed of a material capable of withstanding a steam-sterilization temperature of 121° C. without vapor leakage through the walls thereof; (b) a cap and means for securing said cap to the open top of said bottle; (c) a washer formed of a non-toxic resilient material positioned between the inner surface of the top wall of said cap and the rim of said bottle, said washer serving to absorb pressures developed by expansion of said bottle and prevent deformation of said cap during steam-sterilization thus eliminating leakage therebetween; (d) a blister pack formed of a prescribed polymeric material suitable for use in a steam-sterilization procedure without melting, a closure lid placed along the open side of said blister pack and formed from a non-woven textile material having the characteristics of being steam-permeable, said closure lid being sealed to said polymeric material around the open side thereof and capable of remaining sealed during a steam-sterilization procedure.
Claim 2
Dependent Claim
165 words
A sterile pharmaceutical package comprising: (a) a translucent, resilient polymeric bottle formed of a material capable of withstanding a steam-sterilization temperature of 121° C. without vapor leakage through the walls thereof; (b) a cap and means for securing said cap to the open top of said bottle; (c) a washer formed of a non-toxic resilient material positioned between the inner surface of the top wall of said cap and the rim of said bottle, said washer serving to absorb pressures developed by expansion of said bottle and prevent deformation of said cap during steam-sterilization thus eliminating leakage therebetween; (d) a blister pack formed of a prescribed polymeric material suitable for use in a steam-sterilization procedure without melting, a closure lid placed along the open side of said blister pack and formed from a non-woven textile material having the characteristics of being steam-permeable, said closure lid being sealed to said polymeric material around the open side thereof and capable of remaining sealed during a steam-sterilization procedure.
Claim 3
Dependent Claim
18 words
The sterile pharmaceutical package according to claim 1 wherein said polymeric bottle is formed of a translucent material
Claim 4
Dependent Claim
16 words
The sterile pharmaceutical package according to claim 1 in which said bottle is formed of polypropylene.
Claim 5
Dependent Claim
20 words
The sterile pharmaceutical package according to claim 1 wherein said cap is formed of the same material as said bottle.
Claim 6
Dependent Claim
15 words
The sterile pharmaceutical package according to claim 1 wherein said cap is formed of polypropylene.
Claim 7
Dependent Claim
16 words
The sterile pharmaceutical package according to claim 1 wherein said washer is formed of silicone rubber.
Claim 8
Dependent Claim
21 words
The sterile pharmaceutical package according to claim 1 wherein the prescribed polymeric material used to form said blister pack is polycarbonate.
Claim 9
Dependent Claim
34 words
The sterile pharmaceutical package according to claim 1 and further including a polyester label affixed to the surface of said bottle and extending no more than two-thirds of the way around the circumference thereof.
Claim 10
Dependent Claim
21 words
The sterile pharmaceutical package according to claim 1 and further including a plug-type cannula adapter in the neck of the bottle.
References Cited (Backward Citations)
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Cited
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US3926311A
Cited
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Cited
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Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-10-15 | 1994-04-16 | 1994-10-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-10-15 | 1998-04-16 | 1998-10-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-10-15 | 2002-04-16 | 2002-10-16 | $7700.00 | Window Closed / Lapsed |