US4951683A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for detecting keratoconjunctivitis sicca
Assignee: Individual
•
Filing: 1989-01-19
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Granted: 1990-08-28
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Expires: 2009-01-19
Abstract
Abstract A device for detecting keratoconjunctivitis sicca (KCS) utilizing a probe including a body having an end portion. A plurality of electrical contacts are mounted in spaced configuration at the end portion of the probe body for simultaneous contact with the tear fluid of the ocular conjunctiva, or components thereof. An electrical potential is applied to at least one of the plurality of the electrical contacts and electrical activity, such as conductance, between the one electrical contact to another electrical contact is measured relative and the interposed tear fluid.
Inventors
- 👤 Jeffrey P. Davis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 20:15
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/05; A61B5/053; A61B3/00; A61B3/10; A61B3/101
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
147 words
A device for detecting keratoconjunctivitis sicca in an eye, being usable with an ocular tear fluid on the eyeball in vivo, comprising a. probe means for contacting the ocular tear fluid on the eyeball, said probe means including a body, said body having an end portion with an end surface capable of directly contacting the ocular tear fluid coating the eyeball; b. a plurality of electrical contacts being mounted in spaced configuration and being accessible at said end surface of said end portion of said body to simultaneously communicate with the ocular tear fluid coating the eyeball, c. means for providing an electrical potential on one of said plurality of electrical contacts; and d. means for measuring electrical activity between said one electrical contact and another of said plurality of electrical contacts while said electrical contacts communicate with the ocular tear fluid on the eyeball in vivo.
Claim 2
Independent Claim
147 words
A device for detecting keratoconjunctivitis sicca in an eye, being usable with an ocular tear fluid on the eyeball in vivo, comprising a. probe means for contacting the ocular tear fluid on the eyeball, said probe means including a body, said body having an end portion with an end surface capable of directly contacting the ocular tear fluid coating the eyeball; b. a plurality of electrical contacts being mounted in spaced configuration and being accessible at said end surface of said end portion of said body to simultaneously communicate with the ocular tear fluid coating the eyeball, c. means for providing an electrical potential on one of said plurality of electrical contacts; and d. means for measuring electrical activity between said one electrical contact and another of said plurality of electrical contacts while said electrical contacts communicate with the ocular tear fluid on the eyeball in vivo.
Claim 3
Dependent Claim
17 words
The device of claim 1 in which said end portion includes an exterior surface which is concave.
Claim 4
Dependent Claim
27 words
The device of claim 1 in which said end portion includes an exterior surface which is curved to generally conform to the outer surface of the eye.
Claim 5
Dependent Claim
31 words
The device of claim 1 in which said plurality of electrical contacts includes six contacts in regular hexagonal configuration, and one of said contacts lying at the center of said hexagon.
Claim 6
Dependent Claim
12 words
The device of claim 1 in which said one contact is circular.
Claim 7
Dependent Claim
19 words
The device of claim 1 in which said one contact is split into a first and second linear portion.
Claim 8
Dependent Claim
23 words
The device of claim 1 in which said end portion of said probe includes a membrane forming a chamber in said probe body.
Claim 9
Dependent Claim
25 words
The device of claim 1 which additionally includes means for selectively translating said measured electrical activity into a measurement of tear film osmolarity and osmolality.
Claim 10
Dependent Claim
37 words
The device of claim 1 in which said probe end portion includes an end surface conforming to the curvature of the eye, said plurality of contacts lying adjacent said curved end surface of said probe end portion.
Claim 11
Independent Claim
126 words
A method measuring a characteristic of ocular tear fluid on the eyeball in vivo comprising the steps of: a. mechanically applying a probe to the tear fluid on the eyeball, said probe including a body having an end portion, with an end surface and a plurality of electrical contacts being mounted in spaced relationship and being accessible at said end surface of said end portion of said probe body, said electrical contacts communicating with the tear fluid; on the eyeball b. electrically applying potential to one of said plurality of electrical contacts; and c. measuring the electrical activity between said one electrical contact and another of said plurality of electrical contacts while said electrical contacts communicate with the ocular tear fluid on the eyeball in vivo.
Claim 12
Independent Claim
126 words
A method measuring a characteristic of ocular tear fluid on the eyeball in vivo comprising the steps of: a. mechanically applying a probe to the tear fluid on the eyeball, said probe including a body having an end portion, with an end surface and a plurality of electrical contacts being mounted in spaced relationship and being accessible at said end surface of said end portion of said probe body, said electrical contacts communicating with the tear fluid; on the eyeball b. electrically applying potential to one of said plurality of electrical contacts; and c. measuring the electrical activity between said one electrical contact and another of said plurality of electrical contacts while said electrical contacts communicate with the ocular tear fluid on the eyeball in vivo.
Claim 13
Dependent Claim
27 words
The method of claim 10 which additionally comprises the step of selectively translating said measurement of electrical activity into a measurement of tear fluid osmolarity and osmolality.
Claim 14
Independent Claim
41 words
A method of measuring a characteristic of eye tear fluid in vivo on the eyeballs, comprising the steps of: a. mechanically applying a probe to the in situ tear fluid on the eyeball, said probe including an ion specific electrode; and
Claim 15
Independent Claim
41 words
A method of measuring a characteristic of eye tear fluid in vivo on the eyeballs, comprising the steps of: a. mechanically applying a probe to the in situ tear fluid on the eyeball, said probe including an ion specific electrode; and
Claim 16
Independent Claim
103 words
A device for detecting keratoconjunctivitis sicca in an eye, being usable with an ocular tear fluid on the eyeball, comprising; a. a probe including a body, said body having an end portion with an end surface capable of contacting the ocular tear fluid in vivo on the eyeball, said end surface of said probe end portion generally conforming to the contour of a portion of the eyeball; b. means for detecting ionic electrical activity of the tear fluid in the vicinity of the end surface of said probe end portion; and c. means for metering said ionic electrical activity in the tear fluid.
Claim 17
Independent Claim
103 words
A device for detecting keratoconjunctivitis sicca in an eye, being usable with an ocular tear fluid on the eyeball, comprising; a. a probe including a body, said body having an end portion with an end surface capable of contacting the ocular tear fluid in vivo on the eyeball, said end surface of said probe end portion generally conforming to the contour of a portion of the eyeball; b. means for detecting ionic electrical activity of the tear fluid in the vicinity of the end surface of said probe end portion; and c. means for metering said ionic electrical activity in the tear fluid.
Claim 18
Dependent Claim
18 words
The device of claim 13 in which said means for detecting ionic electrical activity includes an ion-specific electrode.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-08-27 | 1994-02-26 | 1994-08-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-08-27 | 1998-02-26 | 1998-08-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-08-27 | 2002-02-26 | 2002-08-28 | $7700.00 | Window Closed / Lapsed |