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US4950229A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for an electrode used for iontophoresis

Assignee: Vyteris Inc
•
Filing: 1989-09-25
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Granted: 1990-08-21
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Expires: 2009-09-25
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Abstract

Abstract An iontophorectic electrode has a plurality of ion transmitters for establishing electric field lines in an area and a plurality of receivers for accepting ions flowing along the field lines. A plurality of shields are located to resist ion flow between adjacent transmitters and receivers. The transmitters, shields and receivers are in at least a sequence of transmitter, shield, receiver, shield. The electric field lines emanate substantially in one direction and return in substantially the opposite direction. The transmitters and receivers have matrix structures with space to contain ionic medication and electrolyte, respectively. A support for holding a plurality of sequences has current carrying contacts exposed to connect the transmitters and receivers in circuit with a source of electrical power. The preferred method includes establishing an electric field with lines of energy between a plurality of first and second conductors of ions and then passing ions along the energy lines between the conductors. Thereafter the method includes restricting the flow of ions to paths between adjacent first and second conductors and then positioning the first conductors relative to the second conductors so that the energy lines emanate from the first substantially in one direction return to adjacent second conductors in the opposite direction.

Inventors

  • 👤 Burton H. Sage, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 08:39
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0432; A61N1/044; A61N1/18; A61N1/20; A61N1/30; A61N1/303; A61N1/0448

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 164 words
An iontophoretic electrode array for placement against the skin in transdermal transport of ionic solutions through mammalian skin comprising: a plurality of ion transmitters for establishing electric field lines in an area of the skin and for transmission of ions along the field lines, each transmitter having a pair of longer sides and a pair of shorter sides; a plurality of receivers in position for accepting ions flowing along the electric field lines in the area of the skin, each receiver having a pair of longer sides and a pair of shorter sides; and a plurality of shields of a substance to resist the flow of ions thereacross, the shields interposed and located between adjacent transmitters and receivers along the longer sides thereof so that the transmitters, shields and receivers are arranged in at least a sequence of transmitter, shield, receiver, shield so that the electric field lines are generally transverse to the longer sides as they pass through the area of the skin.
Claim 2
Dependent Claim 164 words
An iontophoretic electrode array for placement against the skin in transdermal transport of ionic solutions through mammalian skin comprising: a plurality of ion transmitters for establishing electric field lines in an area of the skin and for transmission of ions along the field lines, each transmitter having a pair of longer sides and a pair of shorter sides; a plurality of receivers in position for accepting ions flowing along the electric field lines in the area of the skin, each receiver having a pair of longer sides and a pair of shorter sides; and a plurality of shields of a substance to resist the flow of ions thereacross, the shields interposed and located between adjacent transmitters and receivers along the longer sides thereof so that the transmitters, shields and receivers are arranged in at least a sequence of transmitter, shield, receiver, shield so that the electric field lines are generally transverse to the longer sides as they pass through the area of the skin.
Claim 3
Dependent Claim 30 words
The electrode array of claim 1 wherein an aspect ratio of the longer to the shorter sides of the respective transmitters and receivers is greater than one and one half.
Claim 4
Dependent Claim 18 words
The electrode array of claim 2 wherein the aspect ratio is in the range of four to twenty.
Claim 5
Dependent Claim 16 words
The electrode array of claim 1 wherein the transmitters include a material having an ionic medication.
Claim 6
Dependent Claim 20 words
The electrode array of claim 4 wherein the material is a porous substance with space therein for the ionic medication.
Claim 7
Dependent Claim 19 words
The electrode array of claim 4 wherein the material is a hydrogel so formulated to include the ionic medication.
Claim 8
Dependent Claim 19 words
The electrode array of claim 4 wherein the material is a hydrogel so formulated to include the ionic medication.
Claim 9
Dependent Claim 15 words
The electrode array of claim 1 wherein the receivers have a material having an electrolyte.
Claim 10
Dependent Claim 19 words
The electrode array of claim 8 wherein the material is a porous substance with space therein for the electrolyte.
Claim 11
Dependent Claim 33 words
The electrode array of claim 1 wherein each transmitter has a matrix structure with space therein for an ionic medication and each receiver has a matrix structure with space therein for an electrolyte.
Claim 12
Dependent Claim 14 words
The electrode array of claim 10 wherein the matrix structure is a porous substance.
Claim 13
Dependent Claim 26 words
The electrode array of claim 1 including a support holding a plurality of the sequences of the transmitters and the receivers separated by the interposed shields.
Claim 14
Dependent Claim 36 words
The electrode array of claim 12 having a source of electrical power wherein the support has current carrying contacts positioned thereon and connecting the transmitters and the receivers in circuit with the source of electrical power.
Claim 15
Dependent Claim 17 words
The electrode array of claim 13 wherein the source of electrical power is carried in the support.
Claim 16
Dependent Claim 32 words
The electrode array of claim 1 wherein the transmitters and the receivers are rectangular plate like in shape with a pair of opposed parallel major surfaces bound by sides set perpendicular thereto.
Claim 17
Dependent Claim 78 words
The electrode array of claim 15 wherein the support has a first set of current carrying contacts connected in circuit with the source of electrical power and positioned thereon and exposed to connect with one of the sides of each of the transmitters and wherein the support has a second set of current carrying contacts positioned thereon and exposed to connect one of the sides of each of the receivers in circuit with the source of electrical power.
Claim 18
Dependent Claim 137 words
The electrode array of claim 16 wherein the first and second sets of the contacts are mounted on the support in spaced apart relation relative to each other and are located on a face thereof, the first set of contacts connected to the transmitters are arranged in circuit for passing current from the source of electrical power to the transmitters and the second set of contacts connected to the receivers are arranged in circuit for receiving ions from the receivers so that there is current flow from the source of electrical power to the transmitters and there is current flow from the receivers to the source of electrical power when ions flow between the sides of the transmitters opposite the first set of contacts and the adjacent sides of the receivers opposite the second set of contacts.
Claim 19
Dependent Claim 61 words
The electrode array of claim 17 wherein the support includes recesses and each of the shields extends beyond the face thereon for the first and second contact sets into one recess in the support so that each recess locates the transmitters and the first set of contacts in circuit and aligns the receivers and the second set of contacts in circuit.

References Cited (Backward Citations)

US2047308A Cited
US4325367A Cited
DE3020789A1 Cited
US4820263A Cited
US4731926A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-08-20 1994-02-19 1994-08-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-08-20 1998-02-19 1998-08-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-08-20 2002-02-19 2002-08-21 $7700.00 Window Closed / Lapsed

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