US4943595A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Perfluorochemicals and process for preparing the same
Assignee: Tanabe Pharma Corp
•
Filing: 1984-02-22
•
Granted: 1990-07-24
•
Expires: 2004-02-22
Abstract
Abstract There is provided a novel perfluorochemical represented by the formula, <IMAGE> wherein RF is a perfluoroalkyl group, a perfluoro alkoxyalkyl group or a perfluoroalkyloxy group, X and X' are same as or different from each other and are a fluorine atom or a perfluoroalkyl group, and Y is a perfluoroalkyloxy group or a perfluoro dialkylamino group, the total number of the carbon atoms contained being an integer of 8 to 11 inclusive. The perfluorochemical is prepared by perfluorinating the corresponding partially fluorinated compound which may have unsaturated hydrocarbon moiety, only with molecular fluorine in a stoichiometric excess amount in an inert solvent. The perfluorochemical is used for preparing a stable emulsion as blood substitutes or perfusion media.
Inventors
- 👤 Kirby V. Scherer, Jr.
- 👤 Kouichi Yamanouchi
- 👤 Kazumasa Yokoyama
- 👤 Ryoichi Naito, deceased
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 16:35
CPC Classifications
C; C07; C07C; C07C43/00; C07C43/02; C07C43/03; C07C43/04; C07C43/12; C07C43/123; C07C43/126; C07C43/14; C07C43/17; C07C43/30; C07C43/313
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
97 words
A perfluoroether derivative suitable for use in a blood substitute and of the formula ##STR65## wherein: R Fl is a C 3 -C 7 perfluoroalkyl group, X 1 is a fluorine atom or a C 1 -C 3 perfluoroalkyl group and X 2 is a C 1 -C 3 perfluoroalkyl group, and RF 2 is a perfluoro C 2 -C 5 -alkyl group, the total number of the carbon atoms contained in the perfluoroalkyl ether derivative being 10 to 11, inclusive, with the proviso that there is at least one branched chain perfluoroalkyl group in the molecule.
Claim 2
Dependent Claim
97 words
A perfluoroether derivative suitable for use in a blood substitute and of the formula ##STR65## wherein: R Fl is a C 3 -C 7 perfluoroalkyl group, X 1 is a fluorine atom or a C 1 -C 3 perfluoroalkyl group and X 2 is a C 1 -C 3 perfluoroalkyl group, and RF 2 is a perfluoro C 2 -C 5 -alkyl group, the total number of the carbon atoms contained in the perfluoroalkyl ether derivative being 10 to 11, inclusive, with the proviso that there is at least one branched chain perfluoroalkyl group in the molecule.
Claim 3
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-n-butoxy-2-methylpentane.
Claim 4
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-isobutoxy-2-methylpentane.
Claim 5
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-sec-butoxy-2-methylpentane.
Claim 6
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-isopentoxy-2-methylpentane.
Claim 7
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-n-propoxy-2,4-dimethylpentane.
Claim 8
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-isopropoxy-2,4-dimethylpentane.
Claim 9
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-n-butoxy-2,4-dimethylpentane.
Claim 10
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-3-isobutoxy-2,4-dimethylpentane.
Claim 11
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-n-butoxy-2-methylpentane.
Claim 12
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-isobutoxy-2-methylpentane.
Claim 13
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-sec-butoxy-2-methylpentane.
Claim 14
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-isopentoxy-2-methylpentane.
Claim 15
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-ethoxy-4-ethyl-4-methylhexane.
Claim 16
Dependent Claim
10 words
The perfluoroalkyl ether derivative of claim 1 which is perfluoro-2-ethoxy-3-isopropyl-4-methylpentane.
Claim 17
Dependent Claim
10 words
An emulsion containing the perfluoroalkyl ether derivative of claim 1.
References Cited (Backward Citations)
US2500388A
Cited
US3242218A
Cited
US3214478A
Cited
US3278615A
Cited
US3435078A
Cited
DE2253534A1
Cited
US4252827A
Cited
US4523039A
Cited
US4510335A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-07-23 | 1994-01-22 | 1994-07-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-07-23 | 1998-01-22 | 1998-07-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-07-23 | 2002-01-22 | 2002-07-24 | $7700.00 | Window Closed / Lapsed |