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US4938960A Expired / Lapsed US ⏱️ 0.0 years remaining

Agents for the treatment and protection of the skin

Assignee: Individual
•
Filing: 1988-06-21
•
Granted: 1990-07-03
•
Expires: 2008-06-21
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Abstract

Abstract The present invention relates to a method for the treatment and protection of human and animal skin which contains vitamin E in a high dose and, in addition, may optionally further contain vitamin C, vitamin A, vitamins of the B series, blood circulation-promoting agents and/or vasodilators, phospholipids, unsaturated fatty acids and/or emulsifiers.

Inventors

  • 👤 Roshdy Ismail

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 18:43
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/67; A61K8/676; A61K31/00; A61K31/33; A61K31/335; A61K31/35; A61K31/352; A61K31/353; A61K31/355; A61K31/365; A61K31/375; A61K8/671; A61K8/673; A61K8/678; A61Q; A61Q17/00; A61Q17/04; A61Q19/00; A61Q19/08; A61Q7/00

Claims Analysis

Total Claims: 52
Claim 1
Independent Claim 64 words
A pharmaceutical composition effective for treatment of skin conditions of allergy, tetter, inflammation, itch, wrinkles and damage from wounds, and for protection of skin from ultraviolet light, comprising at least 200 mg vitamin E per dosage unit and at least one component selected from the group consisting of a blood circulation-promoting agent and a vasodilator, said composition being admixed with a suitable pharmaceutical vehicle.
Claim 2
Dependent Claim 64 words
A pharmaceutical composition effective for treatment of skin conditions of allergy, tetter, inflammation, itch, wrinkles and damage from wounds, and for protection of skin from ultraviolet light, comprising at least 200 mg vitamin E per dosage unit and at least one component selected from the group consisting of a blood circulation-promoting agent and a vasodilator, said composition being admixed with a suitable pharmaceutical vehicle.
Claim 3
Dependent Claim 50 words
The composition according to claim 1, wherein said blood circulation promotor is selected from the group consisting of nicotinic acid benzyl ester, pure arnica oil, calendula oil, heparin sodium, β-Hydroxyethylrutoside, dihydroergotoxine methanesulfonate, dihydroergocristine methanesulphonate, β-hydroxyethylsalic 01. juiperi, 01. pini pumilionis, 01. eucalypti, 01. rosmarinae, Tinct. camphorae, Pentoxifylline or Bencyclan hydrogenfumarate.
Claim 4
Dependent Claim 44 words
The composition according to claim 1 further containing at least one ingredient selected from the group consisting of vitamin C, vitamin A, a vitamin of the B series, at least one unsaturated fatty acid, silicone oil, polysiloxane, an emulsifie:, beta-carotene, and an amino acid.
Claim 5
Dependent Claim 11 words
The composition according to claim 3, wherein said emulsifier is lecithin.
Claim 6
Dependent Claim 29 words
The composition according to claim 3, wherein said unsaturated fatty acid comprises one or more components selected from the group consisting of linoleic acid, linolenic acid, and oleic acid.
Claim 7
Dependent Claim 22 words
The composition according to claim 3, wherein said composition contains from 5,000 to 25,000 International Units of vitamin A per dosage unit.
Claim 8
Dependent Claim 11 words
The composition according to claim 1, further containing ultra-violet light stabilizers.
Claim 9
Dependent Claim 9 words
The composition according to claim 7, further containing antihistaminics.
Claim 10
Dependent Claim 25 words
The composition according to claim 1, wherein said composition further contains up to 12% by weight of Bufexamac, based on the weight of the composition.
Claim 11
Dependent Claim 25 words
The composition according to claim 9, wherein said composition contains from 3 to l0% by weight of Bufexamac, based on the weight of the composition.
Claim 12
Dependent Claim 14 words
The composition according to claim 1, wherein said composition is formulated as a capsule.
Claim 13
Dependent Claim 22 words
The composition according to claim 11, wherein said composition contains for 200 mg to 1,000 mg of vitamin E per dosage unit.
Claim 14
Dependent Claim 22 words
The composition according to claim 12, wherein said composition contains form 250 mg to 600 mg of vitamin E per dosage unit.
Claim 15
Dependent Claim 22 words
The composition according to claim 13, wherein said composition contains for 300 mg to 500 mg of vitamin E per dosage unit.
Claim 16
Dependent Claim 21 words
The composition according to claim 14, wherein said composition contains from 6,000 to 15,000 I.U. of vitamin A per dosage unit.
Claim 17
Dependent Claim 23 words
The composition according to claim 1, wherein said composition is formulated for topical application as a cream, gel, ointment, milk, lotion or solution.
Claim 18
Dependent Claim 26 words
The composition according to claim 16, wherein said composition contains from 0.5 to 20% by weight of vitamin E, based on the weight of the composition.
Claim 19
Dependent Claim 25 words
The composition according to claim 17, wherein said composition contains from 4 to 10% by weight of vitamin E, based on the weight of composition.
Claim 20
Dependent Claim 23 words
The composition according to claim 1, wherein said composition is formulated as spray, tincture or solution in an alcoholic solvent for topical application.
Claim 21
Dependent Claim 12 words
The composition according to claim 19 wherein said solvent is isopropyl alcohol.
Claim 22
Dependent Claim 25 words
The composition according to claim 19, wherein said composition contains up to 32% by weight of vitamin E, based on the weight of the composition.
Claim 23
Dependent Claim 25 words
The composition according to claim 19, wherein said composition contains up to 25% by weight of vitamin E, based on the weight of the composition.
Claim 24
Dependent Claim 22 words
The composition according to claim 16, further containing one or more ingredients selected from the group consisting of lecithin and amino acids.
Claim 25
Dependent Claim 73 words
An ointment for topical administration effective for treatment of skin conditions of allergy, tetter, inflammation, itch, wrinkles and damage from wounds, and for protection of skin from ultra-violet light, comprising from 0.5 to 20% by weight of vitmanin E, based on the weight of the composition, and at least one component selected from the group consisting of a blood circulation-promoting agent and a vasodilator, said composition being admixed with a suitable pharmaceutical vehicle.
Claim 26
Dependent Claim 73 words
An ointment for topical administration effective for treatment of skin conditions of allergy, tetter, inflammation, itch, wrinkles and damage from wounds, and for protection of skin from ultra-violet light, comprising from 0.5 to 20% by weight of vitmanin E, based on the weight of the composition, and at least one component selected from the group consisting of a blood circulation-promoting agent and a vasodilator, said composition being admixed with a suitable pharmaceutical vehicle.
Claim 27
Dependent Claim 49 words
The ointment according to claim 24, wherein said blood circulation promoter is selected from the group consisting of nicotinic acid benzyl ester, pure arnica oil, calendula oil hepario sodium β-Hydroxyethylrutoside, dihydroergotoxine methanesulfonate, dihydroergocristine methanesulphonate, β-hydroxyethylsalicylate, 01. juniperi, 01. pini pumilionis, 01.eucalypti, 01. rosmarinae, Tinct camphorae, Pentoxifylline or Bencyclan hydrogenfumarate.
Claim 28
Dependent Claim 45 words
The ointment according to claim 24, further containing at least one ingredient selected from the group consisting of vitamin C. vitamin A, a vitamin of the B series at least one unsaturated fatty acid, a silicone oil, polysiloxane, an emulsifier, beta-carotene, and an amino acid.
Claim 29
Dependent Claim 11 words
The ointment according to claim 26, wherein said emulsifier is lecithin.
Claim 30
Dependent Claim 12 words
The ointment according to claim 26, further containing ultra violet light stabilizers.
Claim 31
Dependent Claim 29 words
The ointment according to claim 26, wherein said unsaturated fatty acid comprises one or more components selected from the group consisting of linoleic acid, linolenic acid and oleic acid.
Claim 32
Dependent Claim 26 words
The ointment according to claim 24, wherein said ointment contains from 4 to 10% by weight of vitamio E, based on the weight of the composition.
Claim 33
Dependent Claim 25 words
The ointment according to claim 24, wherein said ointment contains up to 32% by weight of vitamin E, based on the weight of the composition.
Claim 34
Independent Claim 58 words
A method of treating skin conditions in a mammal including tetter, inflammation, itch, wrinkles, damage from wounds or exposure to ultra-violet light, comprising the adminstration of an effective dose of a pharmaceutical composition comprising at least 200 mg vitamin E and at least one component selected from the group consisting of a blood circulation-promoting agent an a vasodilator.
Claim 35
Independent Claim 58 words
A method of treating skin conditions in a mammal including tetter, inflammation, itch, wrinkles, damage from wounds or exposure to ultra-violet light, comprising the adminstration of an effective dose of a pharmaceutical composition comprising at least 200 mg vitamin E and at least one component selected from the group consisting of a blood circulation-promoting agent an a vasodilator.
Claim 36
Dependent Claim 24 words
The method of claim 32, wherein said composition further contains up to 12% by weight of Bufexamac, based on the weight of the composition.
Claim 37
Dependent Claim 24 words
The method of claim 33, wherein said composition contains from 3 to 10% by weight of Bufexamac based on the weight of the composition.
Claim 38
Dependent Claim 16 words
The method of claim 32, wherein said composition further contains one or more ultra-violet light stabilizers.
Claim 39
Dependent Claim 12 words
The method of claim 35, wherein said pharaceutical composition further contains antihistamines.
Claim 40
Dependent Claim 49 words
The method of claim 32, wherein said blood circulation promoter is selected from the group consisting of nicotinic acid benzyl ester, pure arnica oil, calaendula oil, heparin sodium β-Hydroxyethylrutoside, dihydroergocristine methanesulfonate, dihydroergocristine methanesulphonate, β-hydroxyethylsalicylate, 01. juniperi, 01. pini pumilionis, 01. eucalypti, 01. rosmarinae, Trinct. camphorae, Pentoxifylline or Bencyclan hydrogenfumarate.
Claim 41
Dependent Claim 12 words
The method of claim 32, wherein said pharmaceutical composition is administered orally.
Claim 42
Dependent Claim 15 words
The method of claim 33, wherein said composition is administered in the form of capsules.
Claim 43
Dependent Claim 19 words
The method of claim 39, wherein each of said capsules contains from 200 to 1,000 mg of vitamin E.
Claim 44
Dependent Claim 18 words
The method claim 40, wherein each of said capsules contains from 250 to 600 mg of vitamin E.
Claim 45
Dependent Claim 19 words
The method of claim 41, wherein each of said capsules contains from 300 to 500 mg of vitamin E.
Claim 46
Dependent Claim 12 words
The method of claim 32, wherein said pharmaceutical composition is administered topically.
Claim 47
Dependent Claim 22 words
The method of claim 43, wherein said composition is administered in the form of a cream, gel, ointment, milk, lotion, or solution.
Claim 48
Dependent Claim 25 words
The method of claim 44, wherein said composition contains from 0.5 to 20% by weight of vitamin E, based on the weight of the composition.
Claim 49
Dependent Claim 25 words
The method of claim 45, wherein said composition contains from 4 to 10% by weight of vitamin E, based on the weight of the composition.
Claim 50
Dependent Claim 23 words
The method of claim 43, wherein said composition is administered in the form of a spray, tincture or solution in an alcoholic solvent.
Claim 51
Dependent Claim 12 words
The method of claim 47, wherein said alcoholic solvent is isopropyl alcohol
Claim 52
Dependent Claim 24 words
The method of claim 48, wherein said composition contains up to 25% by weight of vitamin E, based on the weight of the composition.

References Cited (Backward Citations)

GB964444A Cited
US4144325A Cited
US4454159A Cited
US4525344A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-07-02 1994-01-01 1994-07-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-07-02 1998-01-01 1998-07-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-07-02 2002-01-01 2002-07-03 $7700.00 Window Closed / Lapsed

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