US4933114A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polyacetylenic lipids, radiation-sensitive compositions, photographic elements and processes relating to same
Assignee: Eastman Kodak Co
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Filing: 1981-10-21
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Granted: 1990-06-12
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Expires: 2001-10-21
Abstract
Abstract A photopolymerizable monomer comprising a lipid having at least one hydrophobic acyl chain containing at least two conjugated acetylenic linkages is useful in preparing radiation-sensitive compositions and photographic elements comprising a plurality of liposomes. Further, processes for photopolymerizing the radiation-sensitive compositions and for forming an image in the photographic elements comprise exposing the lipid to radiation, heating the lipid to a temperature equal to or above a first transition temperature of the lipid to render it insensitive to further exposure, and optionally cooling the lipid to a temperature equal to or below a seocnd phase transition temperature of the lipid to render it again sensitive to further exposure. The monomeric lipids, when photopolymerized, form polymeric lipids exhibiting decreased solubility and liposome wall permeability as compared to the unpolymerized monomeric lipids.
Inventors
- 👤 David F. O'Brien
- 👤 Thomas H. Whitesides
- 👤 Richard T. Klingbiel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 20:18
CPC Classifications
C; C08; C08F; C08F38/00; A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K9/1271; A61K9/1273; G; G03; G03F; G03F7/00; G03F7/004; G03F7/025
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
22 words
A lipid monomer which forms bimolecular layer structures having at least one hydrophobic acyl chain containing at least two conjugated acetylenic linkages.
Claim 2
Dependent Claim
22 words
A lipid monomer which forms bimolecular layer structures having at least one hydrophobic acyl chain containing at least two conjugated acetylenic linkages.
Claim 3
Dependent Claim
65 words
The monomer of claim 1 having the formula: ##STR14## wherein: L is the hydrophilic portion of a lipid; A is a hydrophobic acyl chain containing at least two conjugated acetylenic linkages; C is a saturated or unsaturated aliphatic moiety other than A; n is an integer having a value of 1 or greater; and m is an integer having a value of 0 or greater.
Claim 4
Dependent Claim
42 words
The monomer of claim 1 wherein said lipid is selected from the group consisting of phospholipids sphingolipids, glycolipids, glycerides, glycerol ethers, dialkyl phosphates, dialkyl phosphonates, alkylphosphinate monoalkyl esters, phosphonolipids, N,N-disubstituted dimethylammonium halides, trialkylmethylammonium halides, tetraalkylammonium halides, dialkylsulfosuccinic acid esters and 2,3-diacyloxysuccinic acids.
Claim 5
Dependent Claim
100 words
The monomer of claim 1 wherein said lipid is a phospholipid represented by the formula: ##STR15## wherein: X and Y independently are selected from the group consisting of saturated aliphatic and unsaturated aliphatic moieties with the proviso that at least one of X and Y must have at least two conjugated acetylenic linkages; a and b are 0 or 1, and a+b is 1 or 2, with the proviso that when a+b is 1, the X or Y remaining must have at least two conjugated acetylenic linkages; and R is selected from the group consisting of 2-trimethylammonioethyl, ammonioethyl and 2-carboxyammonioethyl.
Claim 6
Dependent Claim
29 words
The monomer of claim 1 wherein said hydrophobic acyl chain has the formula: ##STR16## wherein: n is 2; and x and y independently are integers from 1 to 12.
Claim 7
Dependent Claim
36 words
A phospholipid monomer which forms bimolecular layer structures having the formula: ##STR17## wherein: x and y independently are integers from 1 to 12; and R is selected from the group consisting of 2-trimethylammonioethyl, ammonioethyl and 2-carboxyammonioethyl.
Claim 8
Dependent Claim
36 words
A phospholipid monomer which forms bimolecular layer structures having the formula: ##STR17## wherein: x and y independently are integers from 1 to 12; and R is selected from the group consisting of 2-trimethylammonioethyl, ammonioethyl and 2-carboxyammonioethyl.
Claim 9
Dependent Claim
16 words
The monomer of claim 6 wherein x is 8, y is 9, and R is 2-trimethylammonioethyl.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-11 | 1993-12-11 | 1994-06-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-11 | 1997-12-11 | 1998-06-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-11 | 2001-12-11 | 2002-06-12 | $7700.00 | Window Closed / Lapsed |