US4921915A
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Dispersion polymers, biologically active dispersion polymers, a process for their preparation, and their use as diagnostic aids
Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1987-07-07
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Granted: 1990-05-01
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Expires: 2007-07-07
Abstract
Abstract Dispersion polymers composed of latex, which have on the particle surface a copolymer composed of monomers having terminal acetals of the formula I CH2=CR1-CO-NH-(CH2)n-CH(OR2) (OR3) I in which n=1-6; R1=H or CH3, and R2 and R3 are identical or different with R2 and R3=-(CH2)m-CH3 (m=0-7) or R2 and R3=-CXYZ, X, Y and Z being (CH2)p-CH3 and p being 1-3, with X, Y, Z being identical or different, and betaine compounds of the formula II CH2=CR-(CH2)a-(CO-X)b-Z-(CH2)c-Y II with R=H or CH3, X=-NH or -0, Y=SO3- or COO- <IMAGE> or <IMAGE> a=0-6, b=0-1, c=1-12, are very suitable for the preparation of biologically active latex reagents which have a particularly high detection sensitivity and stability.
Inventors
- 👤 Michael Dengler
- 👤 Wolfgang Kapmeyer
- 👤 Helmut Rinno
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 06:23
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54313; Y; Y10; Y10S; Y10S435/00; Y10S435/963; Y10S436/00; Y10S436/909
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
108 words
A dispersion polymer composed of latex particles on whose surface is located a copolymer which is formed of monomers of the formula I ##STR6## in which n=1-6; R 1 =H or CH 3 , and R 2 and R 3 are identical or different with R 2 and R 3 =--(CH 2 ) m --CH 3 m=0-7 or ##STR7## X, Y and Z being (CH 2 ) p --CH 3 and p being 1-3, with X, Y, Z being identical or different, and monomers of the formula II ##STR8## with R=H or CH 3 , X=--NH or --O, Y=SO 3 - or COO - ##STR9## a=0-6, b=0-1, c=1-12.
Claim 2
Dependent Claim
108 words
A dispersion polymer composed of latex particles on whose surface is located a copolymer which is formed of monomers of the formula I ##STR6## in which n=1-6; R 1 =H or CH 3 , and R 2 and R 3 are identical or different with R 2 and R 3 =--(CH 2 ) m --CH 3 m=0-7 or ##STR7## X, Y and Z being (CH 2 ) p --CH 3 and p being 1-3, with X, Y, Z being identical or different, and monomers of the formula II ##STR8## with R=H or CH 3 , X=--NH or --O, Y=SO 3 - or COO - ##STR9## a=0-6, b=0-1, c=1-12.
Claim 3
Dependent Claim
36 words
A dispersion polymer obtainable by polymerization of a monomer mixture composed of a compound of the formula I and of a compound of the formula II in the presence of a seed dispersion in aqueous medium.
Claim 4
Dependent Claim
36 words
A dispersion polymer obtainable by polymerization of a monomer mixture composed of a compound of the formula I and of a compound of the formula II in the presence of a seed dispersion in aqueous medium.
Claim 5
Dependent Claim
27 words
A dispersion polymer as claimed in claim 1, the monomer of the formula II which is used being N-(omega-sulfoalkyl)-N-acrylamidoalkyl-N,N-dialkylammonium betaine, N-(omega-sulfoalkyl)-N-methacrylamidoalkyl-N,N-dialkylammonium betaine or the corresponding N-(omega-carboxyalkyl) compounds.
Claim 6
Dependent Claim
33 words
A dispersion polymer as claimed in claim 1, the monomer of the formula II which is used being at least one of the compounds N-(3-sulfopropyl)-N-methacryloxyethyl-N,N-dimethylammonium betaine, N-(3-sulfopropyl)-N-methacrylamidopropyl-N,N-dimethylammonium betaine or the corresponding acrylic compounds.
Claim 7
Dependent Claim
20 words
A dispersion polymer as claimed in claim 1, the monomer of the formula II which is used being 1-(3-sulfopropyl)-2-vinylpyridinium betaine.
Claim 8
Dependent Claim
28 words
A dispersion polymer as claimed in claim 1, the monomer of the formula I which is used being N-(2-dialkoxyalkyl)-acrylamide or -methacrylamide where alkyl=C 1 to C 8 .
Claim 9
Dependent Claim
21 words
A dispersion polymer as claimed in claim 1, in which the monomer of the formula I which is used is N-(2-di-n-pentoxyethyl)-methacrylamide.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-04-30 | 1993-10-30 | 1994-05-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-04-30 | 1997-10-30 | 1998-05-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-04-30 | 2001-10-30 | 2002-05-01 | $7700.00 | Window Closed / Lapsed |