US4920209A
Expired / Lapsed
US
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Oral vaccines
Assignee: Wyeth LLC
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Filing: 1987-06-04
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Granted: 1990-04-24
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Expires: 2007-06-04
Abstract
Abstract Methods and vaccines for the production of antibodies to infectious organisms are described. Live recombinant adenovirus containing a foreign gene coding for an antigen produced by another infectious organism is delivered to the intestine of a warm-blooded animal in an enteric-coated dosage form, whereupon the virus infects the gut wall and induces the production of antibodies or cell mediated immunity to both adenovirus and the other infectious organism.
Inventors
- 👤 Alan R. Davis
- 👤 Paul P. Hung
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 22:41
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/63; C12N15/79; C12N15/85; C12N15/86; A; A61; A61K; A61K39/00; C12N2710/00; C12N2710/00011; C12N2710/10011; C12N2710/10311; C12N2710/10322; C12N2710/10341; C12N2710/10343; C12N2720/00; C12N2720/00011; C12N2720/12011; C12N2720/12311; C12N2720/12322; C12N2720/12334; C12N2730/00; C12N2730/00011; C12N2730/10011; C12N2730/10111; C12N2730/10134
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
45 words
A recombinant adenovirus containing a gene coding for an antigen produced by a disease-causing organism said recombinant adenovirus being of type 7; the gene codes for hepatitis-B surface antigen; and the gene is located at delected early region 3; said recombinant adenovirus being ATCC VR2167.
Claim 2
Dependent Claim
45 words
A recombinant adenovirus containing a gene coding for an antigen produced by a disease-causing organism said recombinant adenovirus being of type 7; the gene codes for hepatitis-B surface antigen; and the gene is located at delected early region 3; said recombinant adenovirus being ATCC VR2167.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-04-23 | 1993-10-23 | 1994-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-04-23 | 1997-10-23 | 1998-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-04-23 | 2001-10-23 | 2002-04-24 | $7700.00 | Window Closed / Lapsed |