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US4920045A Expired / Lapsed US ⏱️ 0.0 years remaining

Detection of occult blood in feces

Assignee: Ikagaku Co Ltd
•
Filing: 1988-09-22
•
Granted: 1990-04-24
•
Expires: 2008-09-22
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Abstract

Abstract A method for detection of occult blood in a fecal sample which comprises acting a glycosidase type bacteriolytic enzyme on the fecal sample and subjecting the resulting fecal sample to simultaneous detection of hemoglobin, preferably in combination with transferrin, by an immunological measurement procedure.

Inventors

  • 👤 Shoji Okuda
  • 👤 Kazuo Uchida

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 15:13
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721; G01N33/725; Y; Y10; Y10S; Y10S435/00; Y10S435/973; Y10S436/00; Y10S436/815; Y10S436/825; Y10T; Y10T436/00; Y10T436/25; Y10T436/25125; Y10T436/25375

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 47 words
A method for detection of occult blood in a fecal sample comprising simultaneously reacting said fecal sample with antibodies to hemoglobin and antibodies to transferrin and determining the presence of immunologic reaction products of said hemoglobin and transferrin as an indication of the presence of occult blood.
Claim 2
Independent Claim 47 words
A method for detection of occult blood in a fecal sample comprising simultaneously reacting said fecal sample with antibodies to hemoglobin and antibodies to transferrin and determining the presence of immunologic reaction products of said hemoglobin and transferrin as an indication of the presence of occult blood.
Claim 3
Dependent Claim 32 words
The method according to claim 1, wherein the fecal sample is admixed with a glycosidase capable of lysing bacterial cell walls without decomposing hemoglobin prior to the determination of hemoglobin and transferrin.
Claim 4
Dependent Claim 29 words
The method according to claim 1, wherein the fecal sample is sampled by the use of a spoon or spatula coated with anti-human hemoglobin antibody and anti-human transferrin antibody.
Claim 5
Dependent Claim 11 words
The method according to claim 2, wherein the enzyme is lysozyme.

References Cited (Backward Citations)

US4277250A Cited
US4683197A Cited
US4582811A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-04-23 1993-10-23 1994-04-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-04-23 1997-10-23 1998-04-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-04-23 2001-10-23 2002-04-24 $7700.00 Window Closed / Lapsed

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