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US4913700A Expired / Lapsed US ⏱️ 0.0 years remaining

Culture and transport assembly for percutaneous access device

Assignee: L Vad Technology Inc
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Filing: 1988-10-21
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Granted: 1990-04-03
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Expires: 2008-10-21
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Abstract

Abstract A culture and transport assembly for enclosing a percutaneous access device within a sealed outer container to maintain the device under sterile conditions during transport while accommodating culturing of a coating of dermal cells on a portion of the device while the device is retained within the container. The container has a removable cap to which a culture well body is attached. The percutaneous access device is releasably clamped between the bottom of the body and an underlying platform with a portion of the device projecting into a bore in the body. When the device is so clamped, the bore constituted a sealed culture chamber in which the dermal cell culturing procedure may be performed by introducing cells and culturing solutions into the chamber via fluid passages extending from the chamber to connectors accessible at the exterior of the cap.

Inventors

  • 👤 Adrian Kantrowitz
  • 👤 Paul S. Freed

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 01:30
CPC Classifications
A; A61; A61M; A61M39/00; A61M39/02; A61M39/0247; A61M2039/0288; A61M2039/0291; A61M2039/0294

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 207 words
A culture and transport assembly for a PAD having a disk-like, horizontal base flange and a projection projecting vertically upwardly from the central portion of said base flange, said projection having an exterior surface adapted to have a coating of dermal cells cultured thereon and bonded to said surface, said culture and transport assembly comprising a horizontal platform adapted to support said base flange of said PAD thereon, a culture well body having a bore extending upwardly into said body from the lower end of said body, said bore having a depth and diameter respectively greater than the height of said projection above said base flange and the maximum horizontal dimension of said projection, sealing means on the lower end of said body sealingly engageable with said base flange to seal the lower end of said bore to the upper surface of said base flange in peripherally spaced relationship to said projection to constitute said bore as a culture well enclosing said projection, retention means for detachably clamping said base flange between said sealing means and said platform, and passage means in said body for conducting fluid between said well and the exterior of said body while said sealing means is sealingly engaged with said base flange.
Claim 2
Dependent Claim 207 words
A culture and transport assembly for a PAD having a disk-like, horizontal base flange and a projection projecting vertically upwardly from the central portion of said base flange, said projection having an exterior surface adapted to have a coating of dermal cells cultured thereon and bonded to said surface, said culture and transport assembly comprising a horizontal platform adapted to support said base flange of said PAD thereon, a culture well body having a bore extending upwardly into said body from the lower end of said body, said bore having a depth and diameter respectively greater than the height of said projection above said base flange and the maximum horizontal dimension of said projection, sealing means on the lower end of said body sealingly engageable with said base flange to seal the lower end of said bore to the upper surface of said base flange in peripherally spaced relationship to said projection to constitute said bore as a culture well enclosing said projection, retention means for detachably clamping said base flange between said sealing means and said platform, and passage means in said body for conducting fluid between said well and the exterior of said body while said sealing means is sealingly engaged with said base flange.
Claim 3
Dependent Claim 63 words
The invention defined in claim 1 further comprising a transport container including a cap fixedly secured to and projecting outwardly from the upper end of said body, and a cap-shaped member having an open upper end adapted to be sealingly closed by said cap, said cap when sealed to said container being operable to support said body, PAD and base within said container.
Claim 4
Dependent Claim 150 words
The invention defined in claim 2 wherein said PAD further comprises an elongate flexible catheter mounted within and extending through said PAD and having a first elongate portion projecting downwardly from said base flange and a second elongate portion projecting upwardly from said projection of said PAD, said platform having a central opening therethrough through which said first portion of said catheter projects and means for releasably retaining said first portion of said catheter in a flat coiled storage position beneath said platform, said body having a catheter receiving passage extending upwardly from said well and opening through one side of said body adapted to enable said second portion to extend from said projection through said well and said body to the exterior of said body, and means for releasably retaining that part of said second portion at the exterior of said body coiled about said body beneath said cap.
Claim 5
Dependent Claim 42 words
The invention defined in claim 2 further comprising sealable connecting means mounted upon and accessible from the exterior of said cap is fluid communication with said first passage means for placing said well in fluid communication with the exterior of said container.
Claim 6
Dependent Claim 125 words
A culture and transport assembly for a PAD having a disk-like horizontal base flange and a projection projecting vertically upwardly from the central portion of said base flange, said projection having an exterior surface adapted to have a coating of dermal cells cultured thereon and bonded to said surface; said culture and transport assembly comprising a culture well body having a chamber therein adapted, when said body is sealed at its lower end, to said base flange to define a fluid-tight culture well enclosing said projection in spaced relation to said exterior surface, said body having an upper surface, a cap mounted on said upper surface, and means accessible from the exterior of said cap for conducting fluid through said cap and into said chamber.
Claim 7
Dependent Claim 125 words
A culture and transport assembly for a PAD having a disk-like horizontal base flange and a projection projecting vertically upwardly from the central portion of said base flange, said projection having an exterior surface adapted to have a coating of dermal cells cultured thereon and bonded to said surface; said culture and transport assembly comprising a culture well body having a chamber therein adapted, when said body is sealed at its lower end, to said base flange to define a fluid-tight culture well enclosing said projection in spaced relation to said exterior surface, said body having an upper surface, a cap mounted on said upper surface, and means accessible from the exterior of said cap for conducting fluid through said cap and into said chamber.
Claim 8
Dependent Claim 29 words
The invention defined in claim 5 further comprising a cup-shaped container having an open upper end adapted to sealingly receive said cap to enclose said body and said PAD.

References Cited (Backward Citations)

US4092983A Cited
US4164221A Cited
US4605007A Cited
US4668222A Cited
US4634422A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-04-02 1993-10-02 1994-04-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-04-02 1997-10-02 1998-04-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-04-02 2001-10-02 2002-04-03 $7700.00 Window Closed / Lapsed

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