US4910214A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist
Assignee: Orion Oyj
•
Filing: 1988-07-15
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Granted: 1990-03-20
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Expires: 2008-07-15
Abstract
Abstract The separated d and l enantiomers of medetomidine and their salts are selective and potent α 2 -receptor agonists.
Inventors
- 👤 Arto J. Karjalainen
- 👤 Raimo E. Virtanen
- 👤 Eino J. Savolainen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 05:43
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/54; C07D233/56; C07D233/58; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61P; A61P25/00; A61P25/04; A61P25/20; A61P25/22; A61P9/00; A61P9/06; A61P9/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
14 words
The d enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
14 words
The d enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
46 words
A pharmaceutical composition suitable for use in a method of sedation/analgesia or treatment of anxiety or hypertension comprising the d-enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof in an amount sufficient to produce the desired effect in association with a pharmaceutical carrier.
Claim 4
Dependent Claim
46 words
A pharmaceutical composition suitable for use in a method of sedation/analgesia or treatment of anxiety or hypertension comprising the d-enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof in an amount sufficient to produce the desired effect in association with a pharmaceutical carrier.
Claim 5
Dependent Claim
26 words
A method of sedation/analgesia or treatment of anxiety or hypertension by administration to a subject of an effective amount of an enantiomer according to claim 1.
Claim 6
Dependent Claim
26 words
A method of sedation/analgesia or treatment of anxiety or hypertension by administration to a subject of an effective amount of a composition according to claim 2.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-03-19 | 1993-09-18 | 1994-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-03-19 | 1997-09-18 | 1998-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-03-19 | 2001-09-18 | 2002-03-20 | $7700.00 | Window Closed / Lapsed |