US4902516A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Binder-free granules with delayed release of the active compound
Assignee: CHEMIE HOLDING AKTIENGESELLSCHAFT ST PETER-STRASSE 25 A-4021 LINZ AUSTRIA
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Filing: 1988-04-06
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Granted: 1990-02-20
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Expires: 2008-04-06
Abstract
Abstract Binder-free granules for oral and parenteral administration with delayed release of the active compound, consisting of a pharmaceutical active compound or granules thereof and a coating of 1 to 20% by weight of poly-D(-)-3-hydroxybutyric acid, based on the total weight, and a process for their preparation.
Inventors
- 👤 Werner Korsatko
- 👤 Brigitta Korsatko-Wabnegg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 08:02
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5031
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
63 words
Binder-free granules for oral and parenteral administration with delayed release of the active compound consisting of a pharmaceutical active compound or granules thereof and poly-D(-)-3-hydroxybutyric acid having a molecular weight of about 50,000 to about 800,000, wherein the active compound or granules thereof is/are coated with an amount of 1 to 20% by weight of said poly-D(-)-3-hydroxybutyric acid, based on the total weight.
Claim 2
Dependent Claim
63 words
Binder-free granules for oral and parenteral administration with delayed release of the active compound consisting of a pharmaceutical active compound or granules thereof and poly-D(-)-3-hydroxybutyric acid having a molecular weight of about 50,000 to about 800,000, wherein the active compound or granules thereof is/are coated with an amount of 1 to 20% by weight of said poly-D(-)-3-hydroxybutyric acid, based on the total weight.
Claim 3
Dependent Claim
31 words
Binder-free granules as claimed in claim 1, wherein the active compound or granules thereof is/are coated with an amount of 1 to 15% of poly-D(-)-3-hydroxybutyric acid, based on the total weight.
Claim 4
Dependent Claim
31 words
Binder-free granules as claimed in claim 1, wherein the active compound or granules thereof is/are coated with an amount of 3 to 10% of poly-D(-)-3-hydroxybutyric acid, based on the total weight.
Claim 5
Dependent Claim
13 words
Binder-free granules as claimed in claim 1, wherein the active compound is 7-hydroxyethyltheophylline.
Claim 6
Dependent Claim
21 words
Binder-free granules as claimed in claim 1, wherein the molecular weight of the poly-D(-)-3-hydroxybutyric acid used is between 100,000 and 400,000.
Claim 7
Dependent Claim
14 words
Binder-free granules as claimed in claim 1, wherein the active compound is celiprolol hydrochloride.
Claim 8
Dependent Claim
15 words
Binder-free granules as claimed in claim 1, which have been prepared by fluidized bed granulation.
Claim 9
Dependent Claim
14 words
Binder-free granules as claimed in claim 1, wherein the active compound is hexobendine dichloride.
Claim 10
Dependent Claim
13 words
Binder-free granules as claimed in claim 1, wherein the active compound is ibuprofen.
Claim 11
Dependent Claim
13 words
Binder-free granules as claimed in claim 1, wherein the active compound is dichlofenac-Na.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-02-19 | 1993-08-21 | 1994-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-02-19 | 1997-08-21 | 1998-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-02-19 | 2001-08-21 | 2002-02-20 | $7700.00 | Window Closed / Lapsed |