US4897403A
Expired / Lapsed
US
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Antimalarial compositions and methods
Assignee: United States Department of the Army
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Filing: 1986-11-18
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Granted: 1990-01-30
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Expires: 2006-11-18
Abstract
Abstract An antimalarial composition contains as the active ingredient a mixture of a chemical compound effective in reversing the resistance of cancer cells to chemotherapy drugs and at least one antimalarial agent. A method for treating malaria in mammals comprises administering a composition containing the active ingredient. A method for reducing the resistance of a malarial parasite to an antimalarial agent comprises administering a composition containing the active ingredient.
Inventors
- 👤 Samuel K. Martin
- 👤 Ayo M. J. Oduola
- 👤 Wilbur K. Milhous
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 04:06
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61P; A61P33/00; A61P33/02; Y; Y02; Y02A; Y02A50/00; Y02A50/30
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
33 words
An antimalarial composition containing as the active ingredient a mixture of verapamil and chloroguine or therapeutically acceptable salts of chloroquine, being present in a molar ratio of from about 10:1 to 20,000:1 respectively.
Claim 2
Dependent Claim
33 words
An antimalarial composition containing as the active ingredient a mixture of verapamil and chloroguine or therapeutically acceptable salts of chloroquine, being present in a molar ratio of from about 10:1 to 20,000:1 respectively.
Claim 3
Dependent Claim
27 words
A method for treating malaria in mammals comprising administering to a mammal infected with malaria an antimalarially effective amount of a composition as defined in claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-29 | 1993-07-31 | 1994-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-29 | 1997-07-31 | 1998-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-29 | 2001-07-31 | 2002-01-30 | $7700.00 | Window Closed / Lapsed |