US4892890A
Expired / Lapsed
US
⏱️ 0.0 years remaining
External analgesic compositions
Assignee: GD Searle LLC
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Filing: 1986-05-05
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Granted: 1990-01-09
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Expires: 2006-05-05
Abstract
Abstract The present disclosure relates to an external analgesic solid stick composition for the topical administration of active analgesic agents. The compositions are dimensionally stable solid compositions comprising an external analgesic agent incorporated into a non-reactive hydrophobic wax matrix.
Inventors
- 👤 Nalinkant C. Damani
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 03:02
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/06; Y; Y10; Y10S; Y10S424/00; Y10S424/05
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
138 words
An external analgesic solid stick composition comprising about 10 to 30% by weight of methyl salicylate and about 3 to 16% by weight of menthol incorporated within a non reactive hydrophobic wax matrix comprising (a) about 5 to 25% by weight of stearic acid, about 5 to 25% by weight of stearyl alcohol, together being about 10 to 30% by weight; (b) about 10 to 40% by weight of paraffins, esters of long-chain fatty acids having from 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from 10 to 30 carbon atoms; (c) about 1 to 25% by weight of polyethylene glycol (PEG) esters; (d) about 1 to 20% by weight of non-hydroxylic volatile silicones; and (e) about 3 to 25% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 2
Dependent Claim
138 words
An external analgesic solid stick composition comprising about 10 to 30% by weight of methyl salicylate and about 3 to 16% by weight of menthol incorporated within a non reactive hydrophobic wax matrix comprising (a) about 5 to 25% by weight of stearic acid, about 5 to 25% by weight of stearyl alcohol, together being about 10 to 30% by weight; (b) about 10 to 40% by weight of paraffins, esters of long-chain fatty acids having from 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from 10 to 30 carbon atoms; (c) about 1 to 25% by weight of polyethylene glycol (PEG) esters; (d) about 1 to 20% by weight of non-hydroxylic volatile silicones; and (e) about 3 to 25% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 3
Dependent Claim
114 words
A composition according to claim 1 comprising about 15% by weight of methyl salicylate and about 8% by weight of menthol incorporated within a non-reactive hydrophobic wax matrix comprising (a) about 8% by weight of stearic acid, about 9% by weight of stearyl alcohol; (b) about 30% by weight of paraffins, esters of long-chain fatty acids having from 10 to 30 carbon atoms, or esters of long chain fatty alcohols having from 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non-hydroxylic volatile silicones; and (e) about 15% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 4
Dependent Claim
116 words
A composition according to claim 1 comprising about 30% by weight of methyl salicylate and about 10% by weight of menthol incorporated within a non-reactive hydrophobic wax matrix comprising (a) about 10% by weight of stearic acid, about 3% by weight of stearyl alcohol; (b) about 29% by weight of paraffins, esters of long-chain fatty acids having from about 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from about 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non hydroxylic volatile silicones; and (e) about 3% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 5
Dependent Claim
106 words
An external analgesic solid stick composition comprising 15% by weight of methyl salicylate and 8% by weight of menthol incorporated within a non-reactive hydrophobic wax matrix comprising (a) about 17% by weight of stearyl alcohol; (b) about 30% by weight of paraffins, esters of long-chain fatty acids having from about 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from about 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non-hydroxylic volatile silicones; and (e) about 15% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 6
Dependent Claim
106 words
An external analgesic solid stick composition comprising 15% by weight of methyl salicylate and 8% by weight of menthol incorporated within a non-reactive hydrophobic wax matrix comprising (a) about 17% by weight of stearyl alcohol; (b) about 30% by weight of paraffins, esters of long-chain fatty acids having from about 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from about 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non-hydroxylic volatile silicones; and (e) about 15% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 7
Dependent Claim
105 words
An external analgesic solid stick composition comprising 15% by weight of methyl salicylate and 8% by weight of menthol incorporated within a non-reactive hydrophobic waxy matrix comprising (a) about 17% by weight of stearic acid; (b) about 30% by weight of paraffins, esters of long-chain fatty acids having from 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non- hydroxylic volatile silicones; and (e) about 15% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
Claim 8
Dependent Claim
105 words
An external analgesic solid stick composition comprising 15% by weight of methyl salicylate and 8% by weight of menthol incorporated within a non-reactive hydrophobic waxy matrix comprising (a) about 17% by weight of stearic acid; (b) about 30% by weight of paraffins, esters of long-chain fatty acids having from 10 to 30 carbon atoms, or esters of long-chain fatty alcohols having from 10 to 30 carbon atoms; (c) about 5% by weight of polyethylene glycol (PEG) esters; (d) about 10% by weight of non- hydroxylic volatile silicones; and (e) about 15% by weight of propylene glycol wherein said composition excludes water and reactive lower alcohols.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-08 | 1993-07-10 | 1994-01-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-08 | 1997-07-10 | 1998-01-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-08 | 2001-07-10 | 2002-01-09 | $7700.00 | Window Closed / Lapsed |