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US4892778A Expired / Lapsed US ⏱️ 0.0 years remaining

Juxtaposed laminated arrangement

Assignee: Alza Corp
•
Filing: 1987-05-27
•
Granted: 1990-01-09
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Expires: 2007-05-27
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Abstract

Abstract A dispenser is enclosed for delivering a beneficial agent to an enviroment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, a beneficial agent in the first means, and a second means in the dispenser for aiding in displacing the first means from the dispenser.

Inventors

  • 👤 Felix Theeuwes
  • 👤 Patrick S. L. Wong
  • 👤 Richard Cortese
  • 👤 James B. Eckenhoff

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 02:34
CPC Classifications
A; A61; A61M; A61M31/00; A61M31/002; A61H; A61H31/00; A61K; A61K9/00; A61K9/0002; A61K9/0004; Y; Y10; Y10S; Y10S428/00; Y10S428/913; Y10T; Y10T428/00; Y10T428/24; Y10T428/24942; Y10T428/24992; Y10T428/31504; Y10T428/31511; Y10T428/31855; Y10T428/31909; Y10T428/31971; Y10T428/31975; Y10T428/31978

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 127 words
A juxtaposed laminated arrangement useful for manufacturing a dispenser, which laminate when disposed in the dispenser and the dispenser is in operation administers a beneficial agent to a biological fluid environment of use, wherein the laminated arrangement comprises: a first lamina means for changing from an initial physical state when inside the dispenser to a different physical state when outside the dispenser, which first lamina comprises the beneficial agent and transports the beneficial agent from the dispenser to the biological environment; and, a second lamina means for consuming space inside the dispenser, which second lamina comprises a hydrophilic composition that on contact with fluid from the environment that enters the dispenser absorbs the fluid and thereby exhibits a 2 to 50 fold volume increase for consuming space.
Claim 2
Dependent Claim 127 words
A juxtaposed laminated arrangement useful for manufacturing a dispenser, which laminate when disposed in the dispenser and the dispenser is in operation administers a beneficial agent to a biological fluid environment of use, wherein the laminated arrangement comprises: a first lamina means for changing from an initial physical state when inside the dispenser to a different physical state when outside the dispenser, which first lamina comprises the beneficial agent and transports the beneficial agent from the dispenser to the biological environment; and, a second lamina means for consuming space inside the dispenser, which second lamina comprises a hydrophilic composition that on contact with fluid from the environment that enters the dispenser absorbs the fluid and thereby exhibits a 2 to 50 fold volume increase for consuming space.
Claim 3
Dependent Claim 67 words
The juxtaposed laminated arrangement useful for manufacturing the dispenser for administering the beneficial agent to the biologcal environment of use according to claim 1, wherein the laminated arrangement comprises an additional lamina inteerposed between the first lamina and second lamina, said interposed lamina means for keeping the dispenser in the biological environment by exhibiting a density greater than the density of the biological fluid environment of use.
Claim 4
Dependent Claim 66 words
The juxtaposed laminated arrangement useful for manufacturing the dispenser for administering the beneficial agent to the biological environment of use according to claim 1, wherein the laminated arrangement comprises a third lamina adjacent to the first lamina, said third lamina means for keeping the dispenser in the biological environment by prossessing a specific gravity greater than the specific gravity of the biological fluid environment of use.
Claim 5
Dependent Claim 114 words
A juxtaposed laminated arrangement useful for manufacturing a dispenser for administering a beneficial agent to a biological environment of use, wherein the laminate arrangement comprises: a first lamina means for changing from a first physical state when disposed inside the dispenser to a second physical state outside the dispenser, which lamina comprises a beneficial agent and is a carrier for administering the beneficial agent to the environment of use; and a second lamina means for consuming space when disposed inside the dispenser, which second lamina means comprises a solute that mixes with aqueous fluid present in the environment of use that enters the dispenser and produces a solution that consumes space inside the dispenser.
Claim 6
Dependent Claim 114 words
A juxtaposed laminated arrangement useful for manufacturing a dispenser for administering a beneficial agent to a biological environment of use, wherein the laminate arrangement comprises: a first lamina means for changing from a first physical state when disposed inside the dispenser to a second physical state outside the dispenser, which lamina comprises a beneficial agent and is a carrier for administering the beneficial agent to the environment of use; and a second lamina means for consuming space when disposed inside the dispenser, which second lamina means comprises a solute that mixes with aqueous fluid present in the environment of use that enters the dispenser and produces a solution that consumes space inside the dispenser.
Claim 7
Dependent Claim 65 words
The juxtaposed arrangement useful for manufacturing the dispenser for administering the biological agent to the biological environment of use according to claim 4, wherein the laminated arrangement comprises a third lamina adjacent to the second lamina, said third lamina means for keeping the dispenser in the biological environment by possessing a specific gravity greater than the specific gravity of the biological fluid environmnt of use.
Claim 8
Dependent Claim 50 words
The juxtaposed laminated arrangement useful for manufacturing the dispenser for administering a biological agent to a biological environment of use according to claim 4, wherein the laminated arrangement comprises another lamina between the first and second laminae, said other lamina comprising a dense composition having a density greater than 1.2.

References Cited (Backward Citations)

US3995632A Cited
US4251506A Cited
US4350271A Cited
US4327725A Cited
US4612008A Cited
US4595583A Cited
US4824675A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-01-08 1993-07-10 1994-01-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-01-08 1997-07-10 1998-01-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-01-08 2001-07-10 2002-01-09 $7700.00 Window Closed / Lapsed

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