US4881543A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Combined microwave heating and surface cooling of the cornea
Assignee: TRUSTEES OF DARTMOUTH COLLEGE HANOVER NEW HAMPSHIRE 03756 A CORP OF NH
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Filing: 1988-06-28
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Granted: 1989-11-21
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Expires: 2008-06-28
Abstract
Abstract A non-invasive method and apparatus of reshaping the cornea to correct hyperopia, keratoconus, or myopia is described. The central stroma of the cornea is heated by microwave electromagnetic energy to the shrinkage temperature of collagen. The microwave applicator for heating stroma comprises an open-ended, coaxial antenna driven at 2450 MHz with apparatus for surface cooling of the cornea by flow of saline transverse to the antenna axis.
Inventors
- 👤 B. Stuart Trembly
- 👤 Ralph E. Crump
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:18
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/007; A61F9/0079; A61B; A61B18/00; A61B18/18; A61B18/1815; A61F9/013; A61N; A61N5/00; A61N5/02; A61N5/04; A61B2018/00005; A61B2018/00011; A61B2018/00029; A61F7/00; A61F2007/0054; A61F2007/0056; A61F2007/0059; A61F2007/0063; A61F9/008; A61F2009/00853; A61F2009/00861; A61F2009/00872
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
80 words
An applicator for selectively heating portions of the eye comprising: (a) an antenna means for radiating microwave energy in a pattern to apply a portion of said energy at a predetermined depth within the cornea to elevate the temperature of the cornea tissue at said depth to shrink such tissue; and (b) cooling means for flowing fluid over the outer surface of the cornea to prevent excessive temperature elevation of the cornea surface tissue during radiation of said microwave energy.
Claim 2
Dependent Claim
80 words
An applicator for selectively heating portions of the eye comprising: (a) an antenna means for radiating microwave energy in a pattern to apply a portion of said energy at a predetermined depth within the cornea to elevate the temperature of the cornea tissue at said depth to shrink such tissue; and (b) cooling means for flowing fluid over the outer surface of the cornea to prevent excessive temperature elevation of the cornea surface tissue during radiation of said microwave energy.
Claim 3
Dependent Claim
67 words
The applicator of claim 1 wherein the antenna means has a distal end and a proximal end and comprises a coaxial cable having inner and outer spaced apart conductors coaxial to a central axis and a spacing means is provided coaxial to said cable at the distal end thereof to permit flow of said fluid over said cornea in a path transverse the axis of said cable.
Claim 4
Dependent Claim
28 words
The applicator of claim 2 wherein the spacing means is in the form of a member having an opening transverse to the central axis of the coaxial cable.
Claim 5
Dependent Claim
32 words
The applicator of claim 3 wherein cornea retention means are provided at a side of the spacing means nearest the distal end of the antenna means for minimizing bulging of the cornea.
Claim 6
Dependent Claim
62 words
The applicator of claim 1 wherein the cooling means is comprised of a tubular member having an opening at each end and a sidewall with one end opening being connected to a source of cooling fluid, and a cornea-conforming opening in said sidewall with a circular opening opposite said cornea-conforming opening receiving said antenna means in close proximity with said cornea-conforming opening.
Claim 7
Dependent Claim
23 words
The applicator of claim 5 wherein the microwave energy is in the frequency range of from above 10 MHz to about 10 GHz.
Claim 8
Dependent Claim
114 words
An applicator for selectively heating portions of the cornea stroma while preventing overheating of the epithelium surface thereof comprising: (a) an antenna section having: (i) an antenna means in the form of a coaxial cable having a central axis for radiating electromagnetic energy in a predetermined pattern; (ii) a stand-off member coaxially secured to said cable at a distal end thereof with channels extending through said member transverse a longitudinal axis thereof; and (b) a fluid section having: (i) an applicator tube with an opening at each end and a cornea-conforming opening in the side of said tube adjacent one end and a circular opening opposite said cornea-conforming opening receiving said stand-off member therethrough.
Claim 9
Dependent Claim
114 words
An applicator for selectively heating portions of the cornea stroma while preventing overheating of the epithelium surface thereof comprising: (a) an antenna section having: (i) an antenna means in the form of a coaxial cable having a central axis for radiating electromagnetic energy in a predetermined pattern; (ii) a stand-off member coaxially secured to said cable at a distal end thereof with channels extending through said member transverse a longitudinal axis thereof; and (b) a fluid section having: (i) an applicator tube with an opening at each end and a cornea-conforming opening in the side of said tube adjacent one end and a circular opening opposite said cornea-conforming opening receiving said stand-off member therethrough.
Claim 10
Dependent Claim
36 words
The applicator of claim 7 further including: (a) a housing extending over the circular opening in said tube with an opening therein receiving said stand-off member into said tube in close proximity to said cornea-conforming opening.
Claim 11
Dependent Claim
42 words
The applicator of claim 7 wherein said stand-off member is provided with cornea bulge prevention means in the form of cross-members extending transverse the central axis of the cable at an end of the stand-off member adapted to be nearest the cornea.
Claim 12
Independent Claim
58 words
A method for selectively heating portions of the cornea comprising: (a) radiating microwave energy in a pattern to produce an elevated temperature level below the cornea surface at a predetermined depth within the cornea; (b) while flowing fluid over the outer surface of the cornea to prevent overheating of the cornea surface during radiation of said microwave energy.
Claim 13
Independent Claim
58 words
A method for selectively heating portions of the cornea comprising: (a) radiating microwave energy in a pattern to produce an elevated temperature level below the cornea surface at a predetermined depth within the cornea; (b) while flowing fluid over the outer surface of the cornea to prevent overheating of the cornea surface during radiation of said microwave energy.
Claim 14
Dependent Claim
42 words
The method of claim 10 wherein the energy is radiated by an antenna having a central axis, which antenna is in the form of a coaxial cable and the fluid is flowed in a direction transverse the central axis of said antenna.
Claim 15
Dependent Claim
24 words
The method of claim 11 wherein an adjustable gap is provided between the end of the antenna nearest the cornea and the cornea surface.
Claim 16
Dependent Claim
26 words
The method of claim 12 wherein the adjustable gap is provided by a member having a wedge-shaped opening transverse to the central axis of the antenna.
Claim 17
Dependent Claim
31 words
The method of claim 13 including the step of minimizing bulging of the cornea by cornea retaining means at an end of the member nearest the cornea for retaining the cornea.
Claim 18
Dependent Claim
23 words
The method of claim 10 wherein the microwave energy is in the range of greater than 10 MHz and less than 10 GHz.
Claim 19
Independent Claim
86 words
A method for selectively heating portions of the cornea while preventing overheating of the surface thereof comprising: (a) applying electromagnetic energy to a cornea by radiating said electromagnetic energy in a predetermined pattern from a coaxial cable antenna toward said cornea; (b) providing a stand-off member coaxial to said cable at a distal end thereof with channels extending through said member transverse a longitudinal axis thereof and concurrent with applications of said electromagnetic energy cooling the surface of said cornea by circulating fluid through said channels.
Claim 20
Independent Claim
86 words
A method for selectively heating portions of the cornea while preventing overheating of the surface thereof comprising: (a) applying electromagnetic energy to a cornea by radiating said electromagnetic energy in a predetermined pattern from a coaxial cable antenna toward said cornea; (b) providing a stand-off member coaxial to said cable at a distal end thereof with channels extending through said member transverse a longitudinal axis thereof and concurrent with applications of said electromagnetic energy cooling the surface of said cornea by circulating fluid through said channels.
References Cited (Backward Citations)
US603815A
Cited
US1108686A
Cited
US1364148A
Cited
US2126070A
Cited
US2347915A
Cited
US2525381A
Cited
US3237623A
Cited
US3307533A
Cited
US3978864A
Cited
US3948269A
Cited
US3991770A
Cited
US4003383A
Cited
US4014333A
Cited
US4030480A
Cited
US4140130A
Cited
US4326529A
Cited
US4381007A
Cited
US4528991A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-11-20 | 1993-05-22 | 1993-11-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-11-20 | 1997-05-22 | 1997-11-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-11-20 | 2001-05-22 | 2001-11-21 | $7700.00 | Window Closed / Lapsed |