US4879312A
Expired / Lapsed
US
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Method for enhancing or provoking angiogenesis using angiogenically active omega-3 polyunsaturated fatty acids
Assignee: ANGIO-MEDICAL Corp
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Filing: 1988-03-07
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Granted: 1989-11-07
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Expires: 2008-03-07
Abstract
Abstract The invention teaches the provocation or enhancement of angiogenesis in a subject via the administration of angiogenically active omega-3 polyunsaturated fatty acids. Especially preferred are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Inventors
- 👤 Ahmad R. Kamarei
- 👤 Michael Klibaner
- 👤 Denise Peton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 22:33
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/20
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
33 words
Method for provoking or enhancing angiogenesis in a subject in need of enhanced angiogenic activity comprising locally administering to said subject an angiogenically active omega-3 polyunsaturated fatty acid in an angiogenically effective amount.
Claim 2
Dependent Claim
33 words
Method for provoking or enhancing angiogenesis in a subject in need of enhanced angiogenic activity comprising locally administering to said subject an angiogenically active omega-3 polyunsaturated fatty acid in an angiogenically effective amount.
Claim 3
Dependent Claim
13 words
Method of claim 1, wherein said omega-3 polyunsaturated fatty acid is eicosapentaenoic acid.
Claim 4
Dependent Claim
13 words
Method of claim 1, wherein said omega-3 polyunsaturated fatty acid is docosahexaenoic acid.
Claim 5
Dependent Claim
21 words
Method of claim 1, comprising administering said omega-3 polyunsaturated fatty acid in the form of an ointment, lotion, salve or dressing.
Claim 6
Dependent Claim
28 words
Method of claim 1, wherein said omega-3 polyunsaturated fatty acid is administered in an amount ranging from about 100 μg to about 20 mg per day per subject.
Claim 7
Dependent Claim
34 words
Method for provoking or enhancing angiogenesis in a subject in need of enhanced agiogenic activity consisting of locally administering to said subject an angiogenically active omega-3 polyunsaturated fatty acid in an angiogenically effective amount.
Claim 8
Dependent Claim
34 words
Method for provoking or enhancing angiogenesis in a subject in need of enhanced agiogenic activity consisting of locally administering to said subject an angiogenically active omega-3 polyunsaturated fatty acid in an angiogenically effective amount.
Claim 9
Dependent Claim
12 words
Method of claim 6, wherein said omega-3 polyunsaturated fatty acid is eicosapentanoic.
Claim 10
Dependent Claim
13 words
Method of claim 6, wherein said omega-3 polyunsaturated fatty acid is docosahexaenoic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-11-06 | 1993-05-08 | 1993-11-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-11-06 | 1997-05-08 | 1997-11-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-11-06 | 2001-05-08 | 2001-11-07 | $7700.00 | Window Closed / Lapsed |